Impact Factor 4.400

The 1st most cited open-access journal in Pharmacology & Pharmacy

Original Research ARTICLE

Front. Pharmacol., 28 January 2016 | https://doi.org/10.3389/fphar.2015.00313

Mechanism of Action of the Novel Nickel(II) Complex in Simultaneous Reactivation of the Apoptotic Signaling Networks Against Human Colon Cancer Cells

Nima Samie1,2*, Batoul Sadat Haerian1, Sekaran Muniandy3*, Anita Marlina4, M. S. Kanthimathi3,5, Norbani B. Abdullah4, Gholamreza Ahmadian6 and Raja E. R. Aziddin2
  • 1Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2Drug and Research Unit, Department of Pathology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
  • 3Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 4Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
  • 5Faculty of Medicine, University of Malaya Centre for Proteomics Research, University of Malaya, Kuala Lumpur, Malaysia
  • 6Department of Environmental and Industrial Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran

Citation: Samie N, Haerian BS, Muniandy S, Marlina A, Kanthimathi MS, Abdullah NB, Ahmadian G and Aziddin RER (2016) Mechanism of Action of the Novel Nickel(II) Complex in Simultaneous Reactivation of the Apoptotic Signaling Networks Against Human Colon Cancer Cells. Front. Pharmacol. 6:313. doi: 10.3389/fphar.2015.00313

Received: 19 November 2015; Accepted: 18 December 2015;
Published: 28 January 2016; Retracted: 29 June 2016.

Edited by:

Olivier Cuvillier, Centre National de la Recherche Scientifique, France

Reviewed by:

Stefania Nobili, University of Florence, Italy
Maryna Van De Venter, Nelson Mandela Metropolitan University, South Africa