@ARTICLE{10.3389/fpubh.2018.00205, AUTHOR={Campolina, Alessandro G. and Yuba, Tania Y. and Decimoni, Tassia C. and Leandro, Roseli and Diz, Maria del Pilar Estevez and Novaes, Hillegonda M. D. and de Soárez, Patrícia C.}, TITLE={Health Economic Evaluations of Cancer in Brazil: A Systematic Review}, JOURNAL={Frontiers in Public Health}, VOLUME={6}, YEAR={2018}, URL={https://www.frontiersin.org/articles/10.3389/fpubh.2018.00205}, DOI={10.3389/fpubh.2018.00205}, ISSN={2296-2565}, ABSTRACT={Background: A large number of health economic evaluation (HEE) studies have been published in developed countries. However, Brazilian HEE literature in oncology has not been studied. Objective: To investigate whether the scientific literature has provided a set of HEE in oncology capable of supporting decision making in the Brazilian context.Methods: A systematic review was conducted to identify and characterize studies in this field. We searched multiple databases selecting partial and full HEE studies in oncology (1998-2013).Results: Fifty-five articles were reviewed, of these, 33 (60%) were full health economic evaluations. Type of cancers most frequently studied were: breast (38.2%), cervical (14.6%), lung (10.9%) and colorectal (9.1%). Procedures (47.3%) were the technologies most frequently evaluated. In terms of the intended purposes of the technologies, most (63.6%) were treatments. The majority of the incremental cost-effectiveness ratios (ICERs) reported have been below the cost-effectiveness threshold suggested by the World Health Organization (WHO).Conclusions: There has been an increase in the number of HEEs related to cancer in Brazil. These studies may support decision-making processes regarding the coverage of and reimbursement of healthcare technologies for cancer treatment in Brazil.} }