Frontiers in Aging Neuroscience | Neuroinflammation and Neuropathy

Original Research

Published on 08 Jan 2026

Development and validation of a prognostic nomogram for predicting ventilator-associated pneumonia risk in elderly large vessel occlusion ischemic stroke after endovascular therapy patients

in Neuroinflammation and Neuropathy

Wenfei Liang
Jingling Zhu
Xiuling Yang
Xiaohua He
Guoshun Li
Zhaobang Chen
Jiasheng Zhao
Kangqiang Yang
Bin Liao
Huiquan Deng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1654146

973 views

Review

Published on 17 Dec 2025

Autophagy-mediated regulation of neutrophil inflammatory responses and its relevance to central nervous system diseases

in Neuroinflammation and Neuropathy

Yuliu Li
Yiqing Tan
Wei Zuo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1702993

927 views

Original Research

Published on 11 Dec 2025

Associations between the red blood cell distribution width and 30-day mortality in critically ill patients with delirium: a retrospective study using the MIMIC-IV database

in Neuroinflammation and Neuropathy

Songmei Ma
Lin Lin
Shuwen Zheng
Zhenjing Liu
Li Kong
Haiyun Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1599858

1,540 views

Original Research

Published on 10 Dec 2025

Safety and efficacy of extracranial vertebral artery stenting in elderly patients with symptomatic vertebral artery stenosis

in Neuroinflammation and Neuropathy

Miao Wu
Zhiyong Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1667157

986 views

Original Research

Published on 10 Dec 2025

Prognostic value of endothelial activation and stress index in mechanical thrombectomy for patients with acute ischemic stroke

in Neuroinflammation and Neuropathy

Xiaohua Zhu
Yunnan Lu
Yaojia Xu
Yongxin Li
Qingyong Dai
Xia Chang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1683690

1,070 views

Editorial

Published on 04 Dec 2025

Editorial: Sex-dependent modulation of neuroinflammation in the aging brain

in Neuroinflammation and Neuropathy

Yu-Min Kuo
Shun-Fen Tzeng
Celia Giulietta Fernandez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1745448

1,024 views

Review

Published on 01 Dec 2025

Research progress on the role of microbiome-immune-neurotransmitter network in post-stroke sleep disorders

in Neuroinflammation and Neuropathy

Wanting Shi
Li Wu
Qiong Qin
Yanjing Li
Wei Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1694709

1,961 views

Original Research

Published on 28 Nov 2025

Association of white matter hyperintensity with systemic inflammation markers and cognitive assessments: a cross-sectional study via SHAP analysis

in Neuroinflammation and Neuropathy

Dewang Gao
Jiayu Lv
Xinhui Li
Wen Yong
Wenlong Yu
Lu Wang
Shangjia Ma
Hua Li
Shuaiqiang Zhang
Zi Guo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1667025

1,097 views

Original Research

Published on 17 Nov 2025

Mediating role of muscle quality in the liver–brain axis: integrated analysis of CT markers of body composition, brain aging, and biomarkers

in Neuroinflammation and Neuropathy

Minchul Kim
Chongwon Pae
Joon Ho Moon
Inpyeong Hwang
Kyu Sung Choi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1676721

1,854 views

Original Research

Published on 07 Nov 2025

Astrocytic Ror2-induced imbalance in brain and gut homeostasis contributes to chronic post-thoracotomy pain

in Neuroinflammation and Neuropathy

Chaoqun Liu
Le Shen
Li Xu
Afang Zhu
Yuguang Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1675725

1,610 views

Original Research

Published on 06 Nov 2025

Dynamic decline in estimated glomerular filtration rate associated with in-hospital mortality risk in acute ischemic stroke patients after endovascular therapy: evidence from a Chinese stroke center

in Neuroinflammation and Neuropathy

Yanping Lin
Jingjing She
Lijuan Cai
Lingfeng Yu
Shouyue Jin
Xingyu Chen
Weiwei Gao
Renjing Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1598371

1,231 views

Review

Published on 05 Nov 2025

Brain microenvironment orchestrates highly aggressive tumor variants: current trends and therapeutic approaches

in Neuroinflammation and Neuropathy

Juhi Mishra
John D. Dickinson
Shailendra Kumar Maurya

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1666837

1,814 views

Editorial

Published on 27 Oct 2025

Editorial: Neuroinflammation and distribution of proinflammatory markers in the brain

in Neuroinflammation and Neuropathy

Huazheng Liang
Yong Hao
Yong Bi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1723530

1,351 views

Review

Published on 02 Oct 2025

Role of lipocalin-2 in amyotrophic lateral sclerosis

in Neuroinflammation and Neuropathy

Zhuoya Wang
Wen Cao
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1672903

3,229 views

Original Research

Published on 01 Oct 2025

Western diet-induced visceral adipose tissue inflammation promotes Alzheimer’s disease pathology via microglial activation in a mouse model

in Neuroinflammation and Neuropathy

Ji Sun Lim
Soyoung Kwak
Mi-Hee Yu
Mee-Na Park
Hye Suk Baek
Junho Kang
Jeong-Ho Hong
Jin Kyung Kim
Hye Won Lee
Sang-Woo Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1644988

2,900 views

Mini Review

Published on 25 Sep 2025

Role of store-operated Ca2+ entry and STIM2 in retinal neurodegeneration during glaucoma

in Neuroinflammation and Neuropathy

Sofiia Baranykova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1657590

2,689 views

Opinion

Published on 24 Sep 2025

Regulatory mechanisms of neuro inflammation from a gender perspective: interactions among astrocytes, sex hormones, and the gut-brain axis

in Neuroinflammation and Neuropathy

Jia-Wei Shi
Xiu-Li Meng
Yu Ye
Yi-Ting Wang
He-Xuan Ding
Wen-Xu Qi
Rui Feng
Ke Zhang
Ming Lei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1675694

2,456 views

Original Research

Published on 23 Sep 2025

The impact of ondansetron on clinical outcomes in cranial surgery patients: a propensity-matched analysis of retrospective data

in Neuroinflammation and Neuropathy

Debo Yun
Yongzhen Luo
Rui Li
Wenyong Li
Chunyou Wan
Qinjiang Huang
Jiang Du
Shiyi Zeng
Guangdong Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627353

2,445 views

General Commentary

Published on 11 Sep 2025

Commentary: Sensorimotor dysfunction and postural instability in older adults with type 2 diabetes mellitus: the role of proprioception and neuropathy

in Neuroinflammation and Neuropathy

Datian Chen
Hui Gong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1658306

2,361 views

Review

Published on 08 Sep 2025

Cognitive deterioration in patients undergoing hemodialysis: how variations in age influence the development of new mechanisms and treatment approaches?

in Neuroinflammation and Neuropathy

Hongyu Jiang
Dongyuan He
Yue Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1645702

3,377 views
1 citation

Mini Review

Published on 01 Sep 2025

The estrogen–brain interface in neuroinflammation: a multidimensional mechanistic insight

in Neuroinflammation and Neuropathy

Jie Lu
Tie-Jun Xian
Cheng-Jun Li
Yang Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671552

4,461 views
8 citations

Original Research

Published on 29 Aug 2025

Systemic inflammation versus clinical demographics: patient age surpasses the platelet-to-lymphocyte ratio in differentiating secondary trigeminal neuralgia

in Neuroinflammation and Neuropathy

Zihao Zhang
Qingpei Hao
Tao Wang
Shijun Peng
Xin Chang
Yuepeng Wang
Jia Ouyang
Ruen Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1658854

1,517 views

Mini Review

Published on 29 Aug 2025

Influence of biological sex on neuroinflammatory dynamics in the aging brain

in Neuroinflammation and Neuropathy

Ludmila Müller
Svetlana Di Benedetto
Viktor Müller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1670175

3,906 views
8 citations

Mini Review

Published on 29 Aug 2025

Emerging biomarkers of postoperative delirium at the intersection of neuroinflammation and neurodegeneration

in Neuroinflammation and Neuropathy

Kun Leng
Mervyn Maze
Odmara L. Barreto Chang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632947

4,119 views
4 citations

655 articles

articles

Development and validation of a prognostic nomogram for predicting ventilator-associated pneumonia risk in elderly large vessel occlusion ischemic stroke after endovascular therapy patients

Autophagy-mediated regulation of neutrophil inflammatory responses and its relevance to central nervous system diseases

Associations between the red blood cell distribution width and 30-day mortality in critically ill patients with delirium: a retrospective study using the MIMIC-IV database

Safety and efficacy of extracranial vertebral artery stenting in elderly patients with symptomatic vertebral artery stenosis

Prognostic value of endothelial activation and stress index in mechanical thrombectomy for patients with acute ischemic stroke

Editorial: Sex-dependent modulation of neuroinflammation in the aging brain

Research progress on the role of microbiome-immune-neurotransmitter network in post-stroke sleep disorders

Association of white matter hyperintensity with systemic inflammation markers and cognitive assessments: a cross-sectional study via SHAP analysis

Mediating role of muscle quality in the liver–brain axis: integrated analysis of CT markers of body composition, brain aging, and biomarkers

Astrocytic Ror2-induced imbalance in brain and gut homeostasis contributes to chronic post-thoracotomy pain

Dynamic decline in estimated glomerular filtration rate associated with in-hospital mortality risk in acute ischemic stroke patients after endovascular therapy: evidence from a Chinese stroke center

Brain microenvironment orchestrates highly aggressive tumor variants: current trends and therapeutic approaches

Editorial: Neuroinflammation and distribution of proinflammatory markers in the brain

Role of lipocalin-2 in amyotrophic lateral sclerosis

Western diet-induced visceral adipose tissue inflammation promotes Alzheimer’s disease pathology via microglial activation in a mouse model

Role of store-operated Ca2+ entry and STIM2 in retinal neurodegeneration during glaucoma

Regulatory mechanisms of neuro inflammation from a gender perspective: interactions among astrocytes, sex hormones, and the gut-brain axis

The impact of ondansetron on clinical outcomes in cranial surgery patients: a propensity-matched analysis of retrospective data

Commentary: Sensorimotor dysfunction and postural instability in older adults with type 2 diabetes mellitus: the role of proprioception and neuropathy

Cognitive deterioration in patients undergoing hemodialysis: how variations in age influence the development of new mechanisms and treatment approaches?

The estrogen–brain interface in neuroinflammation: a multidimensional mechanistic insight

Systemic inflammation versus clinical demographics: patient age surpasses the platelet-to-lymphocyte ratio in differentiating secondary trigeminal neuralgia

Influence of biological sex on neuroinflammatory dynamics in the aging brain

Emerging biomarkers of postoperative delirium at the intersection of neuroinflammation and neurodegeneration