Frontiers in Bioengineering and Biotechnology

Original Research

Accepted on 29 Sep 2025

Targeted UDP-Glucose ceramide glucosyltransferase stable overexpression induces a metabolic switch improving cell performance at high cell density

in Synthetic Biology

Marzia Rahimi
Lars Keld Nielsen
Jesús Lavado-García

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1690203

106 views

Original Research

Accepted on 29 Sep 2025

Discovery and optimization of a synthetic small protein domain targeting antibodies

in Synthetic Biology

Ana Margarida Goncalves Carvalho Dias
Manuel Matos
Cátia Soares
Carolina Natal
Ana Sofia Pina
Ana Cecília Roque

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1678111

Review

Published on 26 Sep 2025

Recent advances in Polygonaceae endophytes: diversity, secondary metabolites and biotechnological applications

in Synthetic Biology

Zhi-Min Chen
Rui-Qi Tang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1666908

1,002 views

Original Research

Accepted on 24 Sep 2025

Molecular chaperone effects on recombinant yield and binding characteristics of an ABA-specific scFv in Escherichia coli

in Synthetic Biology

Shimiao Chen
Bin Shan
Yican Luo
Ganhui Mo
Usman Rasheed
Lilan Lv
Xinyu Yang
Qinyu Lu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1643833

300 views

Review

Published on 01 Sep 2025

Regeneration of cofactor NAD(P)+ with NAD(P)H oxidase for the production of value-added chemicals

in Synthetic Biology

Li-Jian Zhou
Shuai-Xi Long
Tong Huan
Yue Wu
Ye-Wang Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1650600

1,811 views

Original Research

Published on 29 Aug 2025

Enhancing lycopene production in Bacillus subtilis by overcoming a critical enzymatic bottleneck

in Synthetic Biology

Esha Rehman
Hawaibam Birla Singh
Minh Phuong Nguyen
Chonglong Wang
Sang-Hwal Yoon
Moonhyuk Kwon
Min-Kyoung Kang
Seon-Won Kim

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1670015

2,220 views

Original Research

Published on 29 Aug 2025

Live culture-based qPCR screening of Taq DNA polymerase variants for resistance to PCR inhibitors

in Synthetic Biology

Milko B. Kermekchiev
Zhian Zhang
Wayne M. Barnes

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1624735

1,633 views

Mini Review

Published on 28 Aug 2025

Yarrowia lipolytica as a promising cell factory for microbial production of value-added nutraceuticals

in Synthetic Biology

Soseon Lee
Ju Hyeon Lee
Hyun June Park
Seung-Ho Baek

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1673169

2,043 views

Editorial

Published on 29 Jul 2025

Editorial: Fusion proteins for the detection of pathogens or pathogen receptors

in Synthetic Biology

Roger M. Benoit

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1660729

1,394 views

Original Research

Published on 04 Jul 2025

A promoter library for tuning gene expression in Cupriavidus necator under autotrophic conditions

in Synthetic Biology

Wataru Kitagawa
Kensuke Igarashi
Ryo Nagasawa
Shigeyuki Kakizawa
Mizuki Horino
Kosuke Fujishima
Toshiaki Fukui
Souichiro Kato

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1595440

2,202 views

Editorial

Published on 26 Jun 2025

Editorial: Microorganisms and microbial technologies for industry and environmental protection

in Synthetic Biology

Jianqiang Lin
Hongbo Hu
Dipesh Dhakal

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1637987

1,194 views

Original Research

Published on 26 Jun 2025

The effect on shikimate production by deleting iolR and metabolic engineering in PTS deficient Corynebacterium glutamicum strain

in Synthetic Biology

Rui Wen Ou
Charles A. Swofford
En-Ze Linda Zhong-Johnson
Cheng Li
Anthony J. Sinskey

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1616558

1,346 views

Original Research

Published on 23 Jun 2025

Enabling and improving trans-nerolidol production by Corynebacterium glutamicum: combining metabolic engineering and trace elements medium refinement

in Synthetic Biology

Jan Seeger
Stella Lohoff
Fabian Schmitfranz
Nadja A. Henke
Volker F. Wendisch

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1621955

1,741 views

Original Research

Published on 09 Jun 2025

Enhancing 10-HDA production of Escherichia coli by heterologous expression of MexHID transporter proteins

in Synthetic Biology

Ziting Xu
Chaofan Du
Sheng Gao
Xinrui Yan
Pan Deng
Yuehan Liu
Junqing Wang
Ruiming Wang
Nan Li

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1590291

1,706 views

Original Research

Published on 03 Jun 2025

“Open science” meets commercial realities: a qualitative study of factors influencing sharing in synthetic biology research in Australia

in Synthetic Biology

Alison McLennan
Sarah Maslen

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1604509

2,614 views

Methods

Published on 20 May 2025

A non-hypothesis-driven practical laboratory activity on functional metagenomics: “fishing” protein-coding DNA sequences from microbiomes

in Synthetic Biology

Melissa Morra
Denise Marradi
Luca Gandini
Vittorio Ivagnes
Giulia Ottolini
Alessandro Bovio
Grace Jabali
Lorenzo Maraschi
Ifeoluwa Ayomide Dada
Tonderai Vitalis Chawanda

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1602982

1,458 views