Frontiers in Cardiovascular Medicine | Cardiovascular Genetics and Systems Medicine

Review

Accepted on 11 Jul 2025

Cardioepigenetics in Action: Aerobic Exercise-Induced Modulation of miRNAs, lncRNAs, and Chromatin Remodeling in Cardiovascular Disease

in Cardiovascular Genetics and Systems Medicine

Ran Qin
Shoudu Yuan
Qi Ye

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1579352

157 views

Original Research

Published on 10 Jul 2025

A case of arrhythmic cardiomyopathy caused by rare multiple gene mutations

in Cardiovascular Genetics and Systems Medicine

Kaiqin Liang
Hong Wang
Minfang Wu
Meng Cui
Kaiyou Liu
Mintao Gan
Wengong Cheng
Aiqiong Huang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1598085

440 views

Original Research

Published on 02 Jul 2025

Disulfidptosis-related gene in acute myocardial infarction and its diagnostic value and functions based on bioinformatics analysis and machine learning

in Cardiovascular Genetics and Systems Medicine

Liwen Chen
Jinru Wei
Guoxiong Deng
Guien Xu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1513342

738 views

Review

Published on 30 Jun 2025

Emerging mechanisms and implications of m6A in CVDs: potential applications of natural products

in Cardiovascular Genetics and Systems Medicine

Hui Wang
Yun Zhang
Xiao Jiang
Guichun Liu
Shujian Xu
Jinbiao He
Xudong He
Ting Xiao
Lijuan Wang
LiJing Xiao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1559064

846 views

Case Report

Published on 24 Jun 2025

Case Report: A heterozygous loss-of-function variant of the ERG gene in a family with vascular pathologies

in Cardiovascular Genetics and Systems Medicine

Philipp Erhart
Nicola Dikow
Eva M. C. Schwaibold
Susanne Dihlmann
Caspar Grond-Ginsbach
Daniel Körfer
Christian P. Schaaf
Sabrina Oeser
Katrin Hinderhofer
Dittmar Böckler

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1550523

692 views

Case Report

Published on 23 Jun 2025

The genomic bases of atrial fibrillation in an Ecuadorian patient: a case report

in Cardiovascular Genetics and Systems Medicine

Rafael Tamayo-Trujillo
Patricia Guevara-Ramirez
Leonel Meza-Chico
Santiago Cadena-Ullauri
Viviana A. Ruiz-Pozo
Elius Paz-Cruz
José Luis Laso-Bayas
Rita Ibarra-Castillo
Ana Karina Zambrano

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1552417

900 views

Original Research

Published on 04 Jun 2025

Interplay of ST2 downregulation and inflammatory dysregulation in hypertrophic cardiomyopathy pathogenesis

in Cardiovascular Genetics and Systems Medicine

Xingyu Cao
Huawei Wang
Zunsong Hu
Wenfang Ma
Peng Ding
Huang Sun
Xiying Guo

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1511415

1,158 views

Case Report

Published on 02 Jun 2025

Case Report: Diverse cardiac and muscular phenotypes in DES c.1024A>G (p.Asn342Asp) variant: a case series with limb weakness as the initial presentation

in Cardiovascular Genetics and Systems Medicine

Liuyang Wang
Dongyue Yue
Zijun Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1590306

786 views

Original Research

Published on 30 May 2025

FOS as a biomarker for myocardial infarction treatment with Deng's Yangxin Decoction: a systems biology-based analysis

in Cardiovascular Genetics and Systems Medicine

Junfeng Fang
Wei Wu
Weifeng He
Lin Wang
Shiyi Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1488684

1,196 views

Case Report

Published on 30 May 2025

Cryo-ablation management of atrial fibrillation in Fabry disease without agalsidase alpha: a case report

in Cardiovascular Genetics and Systems Medicine

Yuanzhu Li
Bi Huang
Suxin Luo

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1483283

1,017 views

Case Report

Published on 23 Apr 2025

Case Report: A FBN1 frameshift-and-nonsense mutation and aortic dissection in Marfan syndrome

in Cardiovascular Genetics and Systems Medicine

Chao Su
Linjun Zeng
Haocheng Lu
Zanxin Wang
Minxin Wei

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1533138

1,970 views

Original Research

Published on 15 Apr 2025

Evaluating the effects of coffee consumption on the structure and function of the heart from multiple perspectives

in Cardiovascular Genetics and Systems Medicine

Xiong-Bin Ma
Yan-Lin Lv
Lin Qian
Jing-Fen Yang
Qian Song
Yong-Ming Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1453106

1,965 views

Original Research

Published on 09 Apr 2025

Pathogenic KCNH2-G53S variant in the PAS domain influences the electrophysiological phenotype in long QT syndrome type 2

in Cardiovascular Genetics and Systems Medicine

Dasom Mun
Ji-Young Kang
Malgeum Park
Gyeongseo Yoo
Nuri Yun
YouMi Hwang
Boyoung Joung

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1524909

1,090 views

Case Report

Published on 09 Apr 2025

Case Report: A novel variant of the TTN gene and two other rare variants in a Chinese patient with dilated cardiomyopathy

in Cardiovascular Genetics and Systems Medicine

Shan Han
Ying-Yi Zhang
Jie Geng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1527544

1,201 views

Case Report

Published on 04 Apr 2025

Identification of a novel NKX2-5 variant in a young Ecuadorian patient with atrioventricular block and bradycardia: a case report

in Cardiovascular Genetics and Systems Medicine

Viviana A. Ruiz-Pozo
Santiago Cadena-Ullauri
Elius Paz-Cruz
Rafael Tamayo-Trujillo
Patricia Guevara-Ramirez
Paul Onofre-Ruiz
Ana Karina Zambrano

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1552423

1,016 views

Original Research

Published on 31 Mar 2025

Neutrophil-related IL1R2 gene predicts the occurrence and early progression of myocardial infarction

in Cardiovascular Genetics and Systems Medicine

Jieqiong Tang
Xierenayi Tudi
Tianxiang Zhang
Jingbo Zhu
Tongtong Shen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1516043

1,457 views