Frontiers in Cardiovascular Medicine

Review

Published on 12 Nov 2025

Investigating the mechanisms of small extracellular vesicles in cardiovascular disease using the living myocardial slice platform

in Heart Valve Disease

Fani Koutentaki
Laura Nicastro
Richard J. R. Kelwick
Paul S. Freemont
Cesare M. Terracciano

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1697099

243 views

Original Research

Accepted on 10 Nov 2025

A DIFFERENCE THAT MATTERS: THE AORTIC ROOT ANATOMY OF LARGE ANIMAL MODELS VERSUS HUMANS

in Heart Valve Disease

Venessa Strauss
Harish Appa
Paul Human
Ferdinand Vogt
Waled Hadasha
Jacques Scherman
Quonita Said-Hartley
Yvonne Schneeberger
Helga Bergmeister
Lenard Conradi

Frontiers in Cardiovascular Medicine

Original Research

Accepted on 10 Nov 2025

Development of a Standardized Ovine Aortic Stenosis Model: A Pathomimetic Platform for TAVI Evaluation and Durability Testing

in Heart Valve Disease

Mengsi Hu
Yan Zhu
Nana Qin
Jie Hou
Baoyin Li
Fangxu Liu
Xin Jiang
Zhuo Chen
Xiongtao Lin
Xiaohang Tong

Frontiers in Cardiovascular Medicine

Original Research

Accepted on 07 Nov 2025

Serum Direct Bilirubin Predicts Severe Tricuspid Regurgitation in Atrial Fibrillation

in Heart Valve Disease

Yao-sheng Wang
Xin-yue Zou
Da-wei Lin
Zhao-xia Wang
Chen Wu
Da-xin Zhou
Chun-yan Shi

Frontiers in Cardiovascular Medicine

189 views

Original Research

Accepted on 04 Nov 2025

In-Silico Assessment of Aortic Valve Function and Mechanics under Hypertension

in Heart Valve Disease

Jason A Shar
Philippe Sucosky

Frontiers in Cardiovascular Medicine

Case Report

Accepted on 03 Nov 2025

Transcatheter Aortic Valve Replacement for Aortic Regurgitation Secondary to Aortic Sinus Dilation with Incidentally Detected Aortic Chordae Tendineae: Case Report

in Heart Valve Disease

Lingli Li
Lulu Liu
Wenjuan Bai

Frontiers in Cardiovascular Medicine

Mini Review

Accepted on 31 Oct 2025

To clip or not to clip? A review of precise risk assessment in the contemporary era of transcatheter edge-to-edge mitral and tricuspid valve repair

in Heart Valve Disease

Felix Ausbuettel
Carlo-Federico Fichera

Frontiers in Cardiovascular Medicine

211 views

Original Research

Published on 31 Oct 2025

Severe mitral stenosis as a cause of paradoxical low-flow, low-gradient severe aortic stenosis: an explorative study on hemodynamics and outcomes

in Heart Valve Disease

Dania Mohty
Mohamed H. Omer
Josef Marek
Omar Ahmad
Waleed Alhemayed
Mohammed F. Janjua
Romain Capoulade
Mohammed Alhumaid
Khadija Alassas
Hani Sergani

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1634914

526 views

Original Research

Accepted on 24 Oct 2025

Burden of non-rheumatic valvular heart disease globally and in China from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021

in Heart Valve Disease

Wen Chen
Jiyong Wei
Xiaoyu Zheng
Yanni Lan
Baoshi Zheng

Frontiers in Cardiovascular Medicine

443 views

Original Research

Published on 23 Oct 2025

Oxidative low-density lipoprotein and shear induced calcification within a calcific aortic valve disease-on-a-chip platform

in Heart Valve Disease

Melissa Mendoza-Seale
Mei-Hsiu Chen
Peter Huang
Gretchen J. Mahler

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1655341

522 views

Systematic Review

Published on 13 Oct 2025

The role of elevated lipoprotein(a) in aortic valve disease: a systematic review

in Heart Valve Disease

P. Wambua
M. Wahinya
Z. Khan

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1610395

1,300 views

Systematic Review

Published on 16 Sep 2025

Prognostic value of left atrial strain in significant aortic valve disease: a systematic review and meta-analysis

in Heart Valve Disease

Na Chen
Wenhui Gu
Jun Wu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1667871

1,491 views

Case Report

Published on 15 Sep 2025

“Mushroom in the heart”: a Volvariella volvacea infective endocarditis case report

in Heart Valve Disease

Yunhan Mao
XinPei Liu
ChaoJi Zhang
Jun Zheng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1643975

1,280 views

Original Research

Published on 09 Sep 2025

Five-year comparative outcomes of the track technique versus conventional artificial chordae sizing in anterior mitral leaflet repair

in Heart Valve Disease

Giuseppe Nasso
Walter Vignaroli
Raffaele Bonifazi
Giovanni Valenti
Flavio Fiore
Dritan Hila
Tommaso Loizzo
Rosalba Franchino
Antongiulio Valenzano
Giacomo Errico

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1642204

1,238 views

Original Research

Published on 01 Sep 2025

Transcatheter edge-to-edge repair for arcade-like mitral apparatus: expanding treatment options and assessing clinical outcome

in Heart Valve Disease

Qinglan Shu
Yi Wang
Cong Lu
Lixue Yin
Yan Deng
Yun Xu
Yi Zhou
Tiantian Luo
Sijia Wang
Jie Zeng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1571818

1,163 views

Original Research

Published on 20 Aug 2025

Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model

in Heart Valve Disease

Imke L. Jansen
Deniz Șahin
Frank J. H. Gijsen
Eric Farrell
Kim van der Heiden

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1629285

1,210 views