Frontiers in Cardiovascular Medicine

Original Research

Published on 23 Oct 2025

Oxidative low-density lipoprotein and shear induced calcification within a calcific aortic valve disease-on-a-chip platform

in Heart Valve Disease

Melissa Mendoza-Seale
Mei-Hsiu Chen
Peter Huang
Gretchen J. Mahler

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1655341

286 views

Review

Accepted on 16 Oct 2025

Investigating the Mechanisms of Small Extracellular Vesicles in Cardiovascular Disease Using the Living Myocardial Slice Platform

in Heart Valve Disease

Fani Koutentaki
Laura Nicastro
Richard J R Kelwick
Paul S Freemont
Cesare M Terracciano

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1697099

193 views

Systematic Review

Published on 13 Oct 2025

The role of elevated lipoprotein(a) in aortic valve disease: a systematic review

in Heart Valve Disease

P. Wambua
M. Wahinya
Z. Khan

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1610395

812 views

Original Research

Accepted on 07 Oct 2025

Severe Mitral Stenosis as a Cause of Paradoxical Low-Flow, Low-Gradient Severe Aortic Stenosis: An Explorative Study on Hemodynamics and Outcomes

in Heart Valve Disease

Dania Mohty
Mohamed H. Omer
Josef Marek
Omar Ahmad
Waleed Alhemayed
Mohamad F Janjua
Romain Capoulade
Mohammed Alhumaid
Khadija Alassas
Hani Sergani

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1634914

236 views

Systematic Review

Published on 16 Sep 2025

Prognostic value of left atrial strain in significant aortic valve disease: a systematic review and meta-analysis

in Heart Valve Disease

Na Chen
Wenhui Gu
Jun Wu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1667871

1,361 views

Case Report

Published on 15 Sep 2025

“Mushroom in the heart”: a Volvariella volvacea infective endocarditis case report

in Heart Valve Disease

Yunhan Mao
XinPei Liu
ChaoJi Zhang
Jun Zheng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1643975

1,181 views

Original Research

Published on 09 Sep 2025

Five-year comparative outcomes of the track technique versus conventional artificial chordae sizing in anterior mitral leaflet repair

in Heart Valve Disease

Giuseppe Nasso
Walter Vignaroli
Raffaele Bonifazi
Giovanni Valenti
Flavio Fiore
Dritan Hila
Tommaso Loizzo
Rosalba Franchino
Antongiulio Valenzano
Giacomo Errico

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1642204

1,148 views

Original Research

Published on 01 Sep 2025

Transcatheter edge-to-edge repair for arcade-like mitral apparatus: expanding treatment options and assessing clinical outcome

in Heart Valve Disease

Qinglan Shu
Yi Wang
Cong Lu
Lixue Yin
Yan Deng
Yun Xu
Yi Zhou
Tiantian Luo
Sijia Wang
Jie Zeng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1571818

1,095 views

Original Research

Published on 20 Aug 2025

Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model

in Heart Valve Disease

Imke L. Jansen
Deniz Șahin
Frank J. H. Gijsen
Eric Farrell
Kim van der Heiden

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1629285

1,138 views

Original Research

Published on 15 Aug 2025

Short-term outcomes of repair vs. replacement for rheumatic mitral valve disease

in Heart Valve Disease

Ming Hou
Wei Zhou
Ning Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1635587

1,415 views

Systematic Review

Published on 12 Aug 2025

Clinical outcomes of transcatheter aortic valve replacement in patients with radiation-induced aortic stenosis: a systematic review and meta-analysis

in Heart Valve Disease

Daniyal Ameen
Nisarg Thakker
Rafael Contreras
Seyyed Mohammad Hashemi
Amir Nasrollahizadeh
Parsa Saberian
Dona Kuriyakose
Ehsan Amini-Salehi
Narsimha Rao Keetha
Sandeep Samethadka Nayak

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1537220

1,802 views

Systematic Review

Published on 11 Aug 2025

Outcomes of transcatheter aortic valve replacement in younger low-risk patients: a comprehensive meta-analysis of efficacy and safety

in Heart Valve Disease

António Rocha de Almeida
Maria Rita Lima
Daniel A. Gomes
Renato Fernandes
Eduardo Infante Oliveira
Pedro Araújo Gonçalves
Rui Campante Teles
Manuel de Sousa Almeida
Lino Patrício

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1586477

1,802 views

Original Research

Published on 01 Aug 2025

Global, regional, and national burden of non-rheumatic valvular heart disease and Its projections to 2035: comprehensive analysis of the global burden of disease study 2019

in Heart Valve Disease

Tao Ying
Qiong Nie
Wei Yan
Han Wang
Jing Wu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1445024

2,179 views

Case Report

Published on 31 Jul 2025

Case Report: Optimized guidewire pacing in transcatheter aortic valve replacement combined with complex PCI in a patient with severe aortic stenosis and regurgitation

in Heart Valve Disease

Ruisong Ma
Wang Liao
Lili Zhang
Sheng Wang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1515954

1,781 views

Brief Research Report

Published on 25 Jun 2025

JUMPSTART pilot: assessing the acceptability and feasibility of a novel early mobilization program following transcatheter aortic valve replacement

in Heart Valve Disease

Marija Corovic
Karen Mosleh
Esha Karia
Sachi Chan
Olivia Puglisi
Jacob Crawshaw
Tasmiya Asif
Tej Sheth
James Velianou
Patrick Magloire

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1568844

1,272 views

Original Research

Published on 25 Jun 2025

GeminiOne transcatheter edge-to-edge repair: comparative hemodynamic and biomechanical evaluation

in Heart Valve Disease

Kai Wang
Dongyang Xu
Bowen Xiao
Zhaoming He
Jianfong Tan
Saibal Kar

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1558454

1,516 views