Frontiers in Cell and Developmental Biology

Original Research

Published on 29 Aug 2025

A human Angelman Syndrome class II pluripotent stem cell line with fluorescent paternal UBE3A reporter

in Stem Cell Research

Gautami R. Kelkar
Samantha R. Stuppy
Dilara Sen
Z. Begum Yagci
Linna Han
Lexi Land
Jessica K. Hartman
Albert J. Keung

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1665693

2,173 views

Review

Published on 20 Aug 2025

The secrets of menstrual blood: emerging frontiers from diagnostic tools to stem cell therapies

in Stem Cell Research

Yige Feng
Yujie He

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1623959

5,352 views

Review

Published on 18 Aug 2025

Mesenchymal stem cell-derived extracellular vesicles: current advances in preparation and therapeutic applications for neurological disorders

in Stem Cell Research

Shuang Li
Jiayi Zhang
Luyao Sun
Ze Yang
Xinxing Liu
Jianling Liu
Xifu Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1626996

3,201 views

Review

Published on 14 Aug 2025

Stem cell therapy offers new hope for the treatment of Alzheimer’s disease

in Stem Cell Research

Guodong He
Jingnan Huang
Zhaodi Zeng
Huiyu Sun
Chao Wu
Qi Xu
Chuanchen Hu
Bei Jin
Minfeng Tong
Chengde Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1650885

3,844 views

Review

Published on 14 Aug 2025

Metabolic and molecular regulation in skeletal muscle dysfunction and regeneration

in Stem Cell Research

Jong Beom Jin
Angelique Robinson
Tori Soukup
Ember Black
André Abit
Shane M. Hammer
Anna Han
Edralin Lucas
Yoo Kim
Jiyoung Bae

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1651553

3,399 views
2 citations

Original Research

Published on 08 Aug 2025

DMP1-mediated transformation of DPSCs to CD31+/CD144+ cells demonstrate endothelial phenotype both in vitro and in vivo

in Stem Cell Research

Amudha Ganapathy
Yinghua Chen
Velavan Bakthavachalam
Anne George

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1630129

1,785 views
1 citation

Review

Published on 30 Jul 2025

Cancer stem cells in personalized therapy: mechanisms, microenvironment crosstalk, and therapeutic vulnerabilities

in Stem Cell Research

Ling Yin
Shoubing Zhou
Hongliang Zhang
Yuhua Shang
Songquan Wu
Tengchuan Jin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1619597

4,939 views
2 citations

Original Research

Published on 30 Jul 2025

Osteogenic shift in the adipose-derived stem cells of Acomys cahirinus is linked to impaired adipose tissue self-renewal

in Stem Cell Research

M. Boldyreva
E. Zubkova
E. Trubkina
M. Agareva
S. Michurina
N. Alekseeva
I. Beloglazova
E. Ratner
Ye Parfyonova
I. Stafeev

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1603405

1,796 views

Editorial

Published on 28 Jul 2025

Editorial: Stem cell research and therapy for liver and kidney diseases

in Stem Cell Research

Daojun Lv
Ting Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1665821

1,672 views

Original Research

Published on 21 Jul 2025

Dysregulation of decidual NK cell proliferation by impaired decidual cells: a potential contributor to excessive trophoblast invasion in placenta accreta spectrum

in Stem Cell Research

You-Zhen Liu
Hsin-Hung Lin
Meng-Shiue Wu
Jin-Chung Shih
Thai-Yen Ling

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1618461

2,160 views
1 citation

Original Research

Published on 17 Jul 2025

Dental pulp stem cells conditioned medium-functionalized microspheres for endodontic regeneration

in Stem Cell Research

Jing Gao
Yuhan Wang
Tongxing Zhang
Jiafei Qu
Qian Liu
Yao Chen
Baoshan Xu
Jing Shen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1627220

2,847 views
2 citations

Review

Published on 17 Jul 2025

The tiny giants of regeneration: MSC-derived extracellular vesicles as next-generation therapeutics

in Stem Cell Research

Tianhe Zhang
Liang Zhang
Xiaoxue Ma
Wenliang Song

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1612589

8,081 views
5 citations

Correction

Published on 11 Jul 2025

Correction: Optimizing Nodal, Wnt and BMP signaling pathways for robust and efficient differentiation of human induced pluripotent stem cells to intermediate mesoderm cells

in Stem Cell Research

Esmeralda Magro-Lopez
Elena Vazquez-Alejo
María de la Sierra Espinar-Buitrago
María Ángeles Muñoz-Fernández

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1655115

1,054 views

Original Research

Published on 11 Jul 2025

Psoralen-mediated regulation of osteogenic differentiation of periodontal ligament stem cells: involvement of the mTOR pathway

in Stem Cell Research

Yujia Wang
Hongbo Zhang
Jie Yu
Jin Jing
Zhaojiang Fu
Yuanping Hao
Qihang Huang
Ruibin Ma
Yingjie Xu
Yingtao Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1634945

1,857 views

Original Research

Published on 10 Jul 2025

Amniotic mesenchymal stem cells attenuate diabetic cardiomyopathy by inhibiting pyroptosis via modulation of the TLR4/NF-κb/NLRP3 pathway

in Stem Cell Research

Xuan Zhou
Shaoliang Xing
Lina Zhang
Jungu Lu
Deming Li
Yating Wang
Yuhang Ma
Weiqin Chang
Manman Su

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1631973

2,027 views
1 citation

Editorial

Published on 07 Jul 2025

Editorial: Advancements in hematopoietic stem cell proliferation and self-renewal maintenance

in Stem Cell Research

Pawan Kumar Raghav
Gurudutta Gangenahalli
Takahiko Hara

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1607145

2,218 views

Original Research

Published on 03 Jul 2025

Age-dependent integration of cortical progenitors transplanted at CSF-neurogenic niche interface

in Stem Cell Research

Gretchen Greene
Nikorn Pothayee
Jahandar Jahanipour
Hyesoo Jie
Jung-Hwa Tao-Cheng
Emily Petrus
Dragan Maric
Alan P. Koretsky

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1577045

2,164 views
1 citation

Methods

Published on 01 Jul 2025

Chromosomal quality control in hPSCs: A practical guide to SNP array analysis with GenomeStudio

in Stem Cell Research

Josephine Haake
Laura Steenpass

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1599923

2,213 views
1 citation

Review

Published on 30 Jun 2025

Nanopathways modulating postoperative cognitive dysfunction: extracellular vesicles

in Stem Cell Research

Yunmeng Zhang
Zengsheng Yin
Zhiyong Zou
Shangzhi Feng
Huayang Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1613378

2,109 views
1 citation

Original Research

Published on 30 Jun 2025

Influence of secretome from porcine cardiosphere-derived cells on porcine macrophage polarization and their possible implications for cardiac remodeling post-myocardial infarction in vitro

in Stem Cell Research

M. Pulido
M. A. de Pedro
A. M. Marchena
V. Alvarez
J. G. Casado
F. M. Sanchez-Margallo
E. López

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1601743

2,516 views

Original Research

Published on 26 Jun 2025

Comparative analysis of small molecule and growth factor-derived human induced pluripotent stem cell-derived hepatocyte-like cells

in Stem Cell Research

Faizal Z. Asumda
Shadia Alzoubi
Kiyasha Padarath
Kimya Jones
Ravindra Kolhe
Ashis Kumar Mondal
Ahmet Alptekin
Wenbo Zhi
Tae Jin Lee
Robert C. Huebert

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1594340

2,152 views

Original Research

Published on 24 Jun 2025

Wharton’s jelly mesenchymal stromal cells derived from preterm umbilical cord reveal a hepatogenic potential

in Stem Cell Research

F. Timoneri
M. Lo Iacono
S. Corrao
G. Alberti
G. Amico
T. Corsello
P. G. Conaldi
Eleonora Russo
G. La Rocca

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1626353

1,996 views
1 citation

Original Research

Published on 23 Jun 2025

Rnd3 deletion affects neuroblast behavior through the RhoA/ROCK pathway but not neural stem cells in postnatal mice subventricular zone

in Stem Cell Research

Amalia Solana-Orts
Germán Belenguer
Begoña Ballester-Lurbe
Olga Gómez
Ignacio Pérez-Roger
José Terrado
Enric Poch
Alexandra Bizy

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1612177

2,192 views

Review

Published on 20 Jun 2025

Current approaches for Usher syndrome disease models and developing therapies

in Stem Cell Research

Fiona K. Leith
Joey Lye
Derek S. Delaney
Samuel McLenachan
Fred K. Chen
Marcus D. Atlas
Elaine Y. M. Wong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1547523

4,454 views
1 citation

1,754 articles

articles

A human Angelman Syndrome class II pluripotent stem cell line with fluorescent paternal UBE3A reporter

The secrets of menstrual blood: emerging frontiers from diagnostic tools to stem cell therapies

Mesenchymal stem cell-derived extracellular vesicles: current advances in preparation and therapeutic applications for neurological disorders

Stem cell therapy offers new hope for the treatment of Alzheimer’s disease

Metabolic and molecular regulation in skeletal muscle dysfunction and regeneration

DMP1-mediated transformation of DPSCs to CD31+/CD144+ cells demonstrate endothelial phenotype both in vitro and in vivo

Cancer stem cells in personalized therapy: mechanisms, microenvironment crosstalk, and therapeutic vulnerabilities

Osteogenic shift in the adipose-derived stem cells of Acomys cahirinus is linked to impaired adipose tissue self-renewal

Editorial: Stem cell research and therapy for liver and kidney diseases

Dysregulation of decidual NK cell proliferation by impaired decidual cells: a potential contributor to excessive trophoblast invasion in placenta accreta spectrum

Dental pulp stem cells conditioned medium-functionalized microspheres for endodontic regeneration

The tiny giants of regeneration: MSC-derived extracellular vesicles as next-generation therapeutics

Correction: Optimizing Nodal, Wnt and BMP signaling pathways for robust and efficient differentiation of human induced pluripotent stem cells to intermediate mesoderm cells

Psoralen-mediated regulation of osteogenic differentiation of periodontal ligament stem cells: involvement of the mTOR pathway

Amniotic mesenchymal stem cells attenuate diabetic cardiomyopathy by inhibiting pyroptosis via modulation of the TLR4/NF-κb/NLRP3 pathway

Editorial: Advancements in hematopoietic stem cell proliferation and self-renewal maintenance

Age-dependent integration of cortical progenitors transplanted at CSF-neurogenic niche interface

Chromosomal quality control in hPSCs: A practical guide to SNP array analysis with GenomeStudio

Nanopathways modulating postoperative cognitive dysfunction: extracellular vesicles

Influence of secretome from porcine cardiosphere-derived cells on porcine macrophage polarization and their possible implications for cardiac remodeling post-myocardial infarction in vitro

Comparative analysis of small molecule and growth factor-derived human induced pluripotent stem cell-derived hepatocyte-like cells

Wharton’s jelly mesenchymal stromal cells derived from preterm umbilical cord reveal a hepatogenic potential

Rnd3 deletion affects neuroblast behavior through the RhoA/ROCK pathway but not neural stem cells in postnatal mice subventricular zone

Current approaches for Usher syndrome disease models and developing therapies