Frontiers in Endocrinology | Systems Endocrinology

Original Research

Published on 24 Nov 2025

Association of triglyceride-glucose index and remnant cholesterol levels with liver fibrosis progression and disease severity in patients with non-alcoholic fatty liver disease: a cross-sectional study

in Systems Endocrinology

Qiong Duan
Yue Wang
Juan Xu
Long Cheng
Wenqing Hong
Pinglu Feng
Wenrui Lu
Xihai Xu
Xu Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1686162

295 views

Editorial

Published on 21 Nov 2025

Editorial: Integrated diagnostics and biomarker discovery in endocrinology and biomedical sciences, volume II

in Systems Endocrinology

Kinam Park
Mikyung Jin
Yong-Min Kwon
Yena Park
Soon-Yong Kwon
Sajung Yun
Youngmi Ji
Sijung Yun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1739424

354 views

Original Research

Published on 19 Nov 2025

Hypersensitive C-reactive protein-atherogenic index as a novel marker for metabolic dysfunction-associated steatotic liver disease in type 2 diabetes mellitus

in Systems Endocrinology

Wei Wang
Yan Ying Chen
Xiu Li Guo
Yan Tong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1721278

389 views

Review

Published on 04 Nov 2025

Chronobiome medicine: circadian regulation of host–microbiota crosstalk in systemic physiology

in Systems Endocrinology

Jhommara Bautista
Andrés López-Cortés

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1691172

1,384 views

Review

Published on 03 Nov 2025

Dysregulated bile acid metabolism as a novel player in gout progression: emerging therapeutic strategies

in Systems Endocrinology

Hui Sun
Le Yang
Ye Sun
Xinya Zhang
Xin Sun
Xueping Zhao
Hui Sun
Qimeng Zhang
Guangli Yan
Xijun Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1676017

774 views

Original Research

Published on 29 Oct 2025

Independent and joint associations of glucose modified by high-density lipoprotein cholesterol with mortality in heart failure patients: evidence from the Jiangxi, China cohort

in Systems Endocrinology

Guoan Jian
Shiming He
Kun Jiang
Zhenyu Wang
Juan Wang
Houhui Lan
Guobo Xie
Guotai Sheng
Yan Fang
Wei Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1680746

572 views

Systematic Review

Published on 29 Oct 2025

Association between thyroid function and metabolic associated fatty liver disease: a systemic review and meta-analysis

in Systems Endocrinology

Wei Xiong
Hua Fan
Jiake Tang
Qingwen Yu
Ziyi Xin
Ting Tang
Xiyun Rao
Lanlan Feng
Yongmin Shi
Xuhan Tong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1660437

863 views

Original Research

Accepted on 27 Oct 2025

Endometriosis burden and trends among women of childbearing age from 1990 to 2021

in Systems Endocrinology

Zhongyun Tang
Chao Ma
Jin Liu
Chongdong Liu

Frontiers in Endocrinology

225 views

Review

Published on 27 Oct 2025

Metabolic dysfunction associated fatty liver disease and type 2 diabetes: pathophysiological links, epidemiological trends, and clinical implications

in Systems Endocrinology

Mohammad Sarif Mohiuddin
Noushin Tabassum Neha
Jawad Ul Karim Mahir
Fardin Al Fahad Shakib
Md. Ashraful Alam
Md. Wahiduzzaman
Rashu Barua
Shakila Jahan Shimu
Mahbubur Rahman
Md. Rafin Hossain

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1669478

2,643 views
1 citation

Review

Published on 23 Oct 2025

Advances in essential oils for metabolic diseases

in Systems Endocrinology

Xinxin Li
Min Tong
Huilian Cao
Xiangjuan Sun
Fenghua Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1684179

1,672 views

Original Research

Published on 16 Oct 2025

A proteome-wide association study reveals novel plasma proteins as potential therapeutic targets for metabolic dysfunction-associated steatotic liver disease

in Systems Endocrinology

Qian Zhong
Yue Zhu
Yiwen Tan
Wenzeng Deng
Chunxia Wang
Shan Yang
Nanwei Tong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1664691

1,479 views

Review

Published on 15 Oct 2025

Inosine: biofunctions and the roles in human diseases

in Systems Endocrinology

Fangwei Li
Jiawen Zhang
Jiayi Kang
Xuemei Tong
Ping Zhang
Yemin Zhu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1634814

1,742 views

Original Research

Published on 15 Oct 2025

Characteristics of the gut microbiome of asymptomatic hyperuricemia

in Systems Endocrinology

Fengjiao Cao
Wenming Yi
Mengwei Wu
Ao Gao
Tianlun Kang
Xiujuan Hou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1557225

1,927 views

Original Research

Published on 10 Oct 2025

Establishment and evaluation of a model for clinical feature selection and prediction in gout patients with cardiovascular diseases: a retrospective cohort study

in Systems Endocrinology

Bingbing Fan
Yuqing Ye
Zihan Wang
Yuanyuan Xu
Meishan Lu
Weihong Cong
Fang Ma

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1599028

1,942 views

Original Research

Published on 22 Sep 2025

The association between gestational hypothyroidism in pregnant women with preeclampsia, maternal liver function indicators, and neonatal birth weight: a study in Chinese pregnant women

in Systems Endocrinology

Fang Zhang
Qing Hua
Xiaoyan You
Fenglian Shi
Yadan Zhou
Xia Xu
Xiaona Tian
Gang Tian
Li Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1555277

2,523 views

Review

Published on 10 Sep 2025

Metabolic and genetic mechanisms of metabolic dysfunction-associated steatotic liver disease: an integrative perspective from molecular pathways to clinical challenges

in Systems Endocrinology

Jingyuan Ma
Yanna Ma
Xing Wan
Junchen Li
Yunshu Zhang
Jifeng Liu
Yunhai Gao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1639064

3,430 views