Frontiers in Endocrinology | Systems Endocrinology

Original Research

Accepted on 16 Oct 2025

Independent and Joint Associations of Glucose Modified by High-Density Lipoprotein Cholesterol with Mortality in Heart Failure Patients: Evidence from the Jiangxi, China Cohort

in Systems Endocrinology

Guoan Jian
Shiming He
Kun Jiang
Zhenyu Wang
Juan Wang
Houhui Lan
Guobo Xie
Guotai Sheng
Yan Fang
Wei Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1680746

Original Research

Published on 16 Oct 2025

A proteome-wide association study reveals novel plasma proteins as potential therapeutic targets for metabolic dysfunction-associated steatotic liver disease

in Systems Endocrinology

Qian Zhong
Yue Zhu
Yiwen Tan
Wenzeng Deng
Chunxia Wang
Shan Yang
Nanwei Tong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1664691

480 views

Review

Published on 15 Oct 2025

Inosine: biofunctions and the roles in human diseases

in Systems Endocrinology

Fangwei Li
Jiawen Zhang
Jiayi Kang
Xuemei Tong
Ping Zhang
Yemin Zhu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1634814

824 views

Original Research

Published on 15 Oct 2025

Characteristics of the gut microbiome of asymptomatic hyperuricemia

in Systems Endocrinology

Fengjiao Cao
Wenming Yi
Mengwei Wu
Ao Gao
Tianlun Kang
Xiujuan Hou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1557225

1,084 views

Systematic Review

Accepted on 13 Oct 2025

Association between thyroid function and metabolic associated fatty liver disease:a systemic review and meta-analysis

in Systems Endocrinology

Wei Xiong
Hua Fan
Jiake Tang
Qingwen Yu
Ziyi Xin
Ting Tang
Xiyun Rao
Lanlan Feng
Yongmin Shi
Xuhan Tong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1660437

266 views

Original Research

Published on 10 Oct 2025

Establishment and evaluation of a model for clinical feature selection and prediction in gout patients with cardiovascular diseases: a retrospective cohort study

in Systems Endocrinology

Bingbing Fan
Yuqing Ye
Zihan Wang
Yuanyuan Xu
Meishan Lu
Weihong Cong
Fang Ma

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1599028

1,326 views

Review

Accepted on 02 Oct 2025

Metabolic dysfunction associated fatty liver disease and Type 2 Diabetes: Pathophysiological Links, Epidemiological Trends, and Clinical Implications

in Systems Endocrinology

Mohammad Sarif Mohiuddin, MD, PhD
Noushin Tabassum Neha
Jawad Ul Karim Mahir
Fardin Al Fahad Shakib
Md Ashraful Alam
Md Wahiduzzaman
Rashu Barua
Shakila Jahan Shimu
Md. Mahbubur Rahman
Md Rafin Hossain

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1669478

622 views

Review

Accepted on 01 Oct 2025

Advances in Essential Oils for Metabolic Diseases

in Systems Endocrinology

Li Xinxin
Min Tong
Huilian Cao
Xiangjuan Sun
Fenghua Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1684179

376 views

Original Research

Published on 22 Sep 2025

The association between gestational hypothyroidism in pregnant women with preeclampsia, maternal liver function indicators, and neonatal birth weight: a study in Chinese pregnant women

in Systems Endocrinology

Fang Zhang
Qing Hua
Xiaoyan You
Fenglian Shi
Yadan Zhou
Xia Xu
Xiaona Tian
Gang Tian
Li Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1555277

1,931 views

Review

Published on 10 Sep 2025

Metabolic and genetic mechanisms of metabolic dysfunction-associated steatotic liver disease: an integrative perspective from molecular pathways to clinical challenges

in Systems Endocrinology

Jingyuan Ma
Yanna Ma
Xing Wan
Junchen Li
Yunshu Zhang
Jifeng Liu
Yunhai Gao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1639064

2,198 views

Correction

Published on 05 Sep 2025

Correction: Triglyceride-glucose index and periodontitis: evidence from two population-based surveys

in Systems Endocrinology

Jing Huang
Dan Zhang
Hua Li
Yiyun Zhang
Tianxue Long
Xiaojing Guo
Hangyu Cui
Zixuan Wei
Jun Zhao
Mingzi Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1686929

1,406 views

Original Research

Published on 02 Sep 2025

The biological and immunological significance of the estrogen-related gene IER3 in diabetes

in Systems Endocrinology

Da Ke
Xian He
Wenzhe Li
Hongyan Wu
Yaling Sun
Jie Tan
Ya Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1570332

1,588 views

Original Research

Published on 28 Aug 2025

Elevated total cholesterol in healthy adults mediates the association between impaired thyroid hormone sensitivity and hyperuricemia

in Systems Endocrinology

Xiying Huang
Daojun Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1625843

1,387 views

Review

Published on 27 Aug 2025

Metabolic disturbances in acute pancreatitis: mechanisms and therapeutic implications

in Systems Endocrinology

Chao Fang
Yingwei Ding
Xiaojun Wang
Xusheng Teng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1579457

1,660 views

Original Research

Published on 04 Aug 2025

Mathematical modeling of the interaction between endocrine systems and EEG signals

in Systems Endocrinology

Wei Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1543185

1,289 views

Original Research

Published on 01 Aug 2025

Association between serum anion gap trajectory and mortality in hospitalized patients with sepsis: an analysis of the MIMIC-IV database

in Systems Endocrinology

Lijuan Jing
Xiaopeng Shi
Lijun Xu
Xiangmei Zhao
Faliang Li
Lijie Qin

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1578078

2,127 views