Frontiers in Genetics

Original Research

Published on 10 Sep 2025

Diphenyl pyridine intervention improves S. aureus-induced pneumonia by globally regulating transcriptome profile

in Computational Genomics

Wei Duan
Qingfeng Zhu
Hai Ci
Jingang Zhang
Zhiwei Tian
Wanyu Li
Zhengfu Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1624327

1,764 views

Original Research

Published on 10 Sep 2025

Clinical utility of exome sequencing in hearing loss: a retrospective cohort study

in Genetics of Common and Rare Diseases

Chang Liu
Yanlin Huang
Anpeng Fu
Yunan Wang
Jing Wu
Yan Zhang
Li Du
Hongke Ding
Lihua Yu
Fake Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1643537

2,416 views

Original Research

Published on 10 Sep 2025

Genome-wide evolution and function analysis of ALOG gene family in cotton

in Computational Genomics

Zhen Liu
Siyu Shen
Zhijuan Cui
Tao Wang
Pengtao Li
Yangyang Wei
Renhai Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1625634

1,852 views
1 citation

Correction

Published on 10 Sep 2025

Correction: Identification and functional characteristics of a novel splice site variant in L1CAM caused X-linked hydrocephalus

in Genetics of Common and Rare Diseases

Shijie Zhou
Hao Zhang
Xue Li
Quan Chen
Zhihong Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1676267

1,255 views

Original Research

Published on 09 Sep 2025

Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition

in Cancer Genetics and Oncogenomics

Gizem Onder
Ozkan Ozdemir
Fulya Taylan
Cengiz Canpolat
Koray Yalcin
Fatih Erbey
Banu Oflaz Sozmen
Fikret Asarcikli
Turan Bayhan
Yunus Murat Akcabelen

Frontiers in Genetics

doi 10.3389/fgene.2025.1624306

4,385 views

Original Research

Published on 09 Sep 2025

Prediction of NR3C1 as a methylation marker for the prevention and treatment of gastric cancer in Rhizoma Atractylodis Macrocephalae based on machine learning algorithm and bioinformatics analysis

in Epigenomics and Epigenetics

Shicong Huang
Qian Gu
Yan Chen
Xiaofang Huang
Yuhua Du
Ziying Zhou
Yi Nan
Ling Yuan

Frontiers in Genetics

doi 10.3389/fgene.2025.1584986

3,400 views

Original Research

Published on 09 Sep 2025

ZC3H18 regulates alternative splicing and related genes in cervical cancer

in Cancer Genetics and Oncogenomics

Wenjuan Chen
Chenying Liu
Siyi Li
Xingyun Xie
Dan Hu
Yaobin Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1621238

2,440 views

Original Research

Published on 08 Sep 2025

Constructing a neutrophil extracellular trap model based on machine learning to predict clinical outcomes and immune therapy responses in oral squamous cell carcinoma

in RNA

Jian Wang
Zhenzhen Li
Zhiwei Li
Zijing Yu
Wenpin Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1616868

3,816 views
1 citation

Original Research

Published on 08 Sep 2025

Comprehensive analysis and validation of angiogenesis in vascular dementia from the perspective of diagnosis, prevention, and treatment

in Human and Medical Genomics

Lijun Xu
Yujiao Wang
Daojun Xie

Frontiers in Genetics

doi 10.3389/fgene.2025.1646991

2,944 views

Original Research

Published on 08 Sep 2025

A lipid metabolism and lysosome-based risk signature for prognosis and immune response prediction in uterine corpus endometrial carcinoma

in Cancer Genetics and Oncogenomics

Yuanyuan Zhu
Pusheng Yang
Shu Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1594682

2,638 views

Review

Published on 08 Sep 2025

Mechanisms and recent advances in non-coding RNAs and RNA modifications in antiplatelet drug resistance

in RNA

Ping Ni
Kejie Chen
Jing Xiang
Haifeng Shao
Xiaoling Chen
Qiao Chen
Lingling Wang
Junli Hao
Xinyi Huang
Qing Cao

Frontiers in Genetics

doi 10.3389/fgene.2025.1618105

2,585 views

Original Research

Published on 05 Sep 2025

Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis

in Computational Genomics

Yeqing Yu
Chengwei Yu
Shanshan Dai
Yixu Liu
Lanlan Hu
Weimin Lu

Frontiers in Genetics

doi 10.3389/fgene.2025.1617834

3,338 views

Original Research

Published on 05 Sep 2025

Geographical distribution of ALDH2 rs671 polymorphism in Chinese angina pectoris patients

in Genetics of Common and Rare Diseases

Wenjia Dong
Junjie Yu
Siqi Xu
Hongsheng Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1543963

2,274 views

Original Research

Published on 05 Sep 2025

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

in Cancer Genetics and Oncogenomics

Pengpeng Gui
Zhengyi Han
Zhenyu Yin
Peng Cao
Xin Zhou
Yan Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1593314

2,976 views

Original Research

Published on 05 Sep 2025

Temporal regulation of genetic programs governing multiple cell death during myocardial ischemia-reperfusion injury

in Genetics of Common and Rare Diseases

Qiuyu Pang
Xiangmin Meng
Zhenfang Zhou
Lu You
Jinghan Yuan
Qipu Feng
Bingmei Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1632867

2,627 views
2 citations

Original Research

Published on 03 Sep 2025

3D-cultured hADSCs-derived exosomes deliver circ_0011129 to synergistically attenuate skin photoaging

in Genetics of Aging

Yu Zhang
Feng Zhou
Gang Nie
Liang Li
Juan Wen
Shimin He
Amin Yao

Frontiers in Genetics

doi 10.3389/fgene.2025.1627472

3,776 views

Original Research

Published on 03 Sep 2025

Integrating BERT pre-training with graph common neighbours for predicting ceRNA interactions

in RNA

Zhengxing Xie
Tianping Ying
Ge Jing
Shiyang Liang
Junhua Liu
Lianghua Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1606016

1,891 views

Original Research

Published on 03 Sep 2025

Validation of a genome-wide polygenic score for body mass index in South Asians

in Genetics of Common and Rare Diseases

Ramesh Menon
Nikhat Khan
Sandeep Charugulla
Akshi Bassi
Pooja Dangare
Akshay Dedaniya
Aakanksha Pant
Rammurthy Anjanappa
Praveena L. Samson
Uthra Satagopan

Frontiers in Genetics

doi 10.3389/fgene.2025.1603542

2,433 views

Perspective

Published on 03 Sep 2025

From reading to writing genomes: a new direction in ELSI

in ELSI in Science and Genetics

Koichi Mikami

Frontiers in Genetics

doi 10.3389/fgene.2025.1667769

3,165 views

Original Research

Published on 03 Sep 2025

Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

in Computational Genomics

Ning Zhang
Ye Zhang
Rui-Fei Yang
Min Tan
Hai-Qing Chu
Abdur Rehman
Lu-Yu Yang
Ya-Yu Li
Fahad M. Alshabrmi
Xin Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1614254

4,447 views
2 citations

Data Report

Published on 01 Sep 2025

Data report: transcriptome profiling of 13 tissues of Junmu No. 1 boars

in RNA

Chunyan Bai
Jiayi Ning
Junwen Fei
Zhenbo Wang
Yu He
Jing Li
Xiaoran Zhang
Shuang Liang
Dali Wang
Hao Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1641395

2,356 views

Original Research

Published on 01 Sep 2025

Mining for gene-environment and gene-gene interactions: parametric and non-parametric tests for detecting variance quantitative trait loci

in Statistical Genetics and Methodology

Wan-Yu Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1617504

2,882 views

Original Research

Published on 01 Sep 2025

A de novo mutation in RAB11A is associated with neurodevelopmental disorder accompanied by variable multisystem abnormalities

in Genetics of Common and Rare Diseases

Huiting Zhang
Jingtao Zhang
Xue Ma
Zhehui Chen
Ying Jin
Mengqiu Li
Hui Dong
Feng Gu
Yao Zhang
Yanling Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1636206

2,207 views

Editorial

Published on 01 Sep 2025

Editorial: Mitochondria in metabolic reprogramming and immune activation: the key gene and therapeutic target

in Immunogenetics

Yongzheng Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1686852

2,875 views

16,574 articles

articles

Diphenyl pyridine intervention improves S. aureus-induced pneumonia by globally regulating transcriptome profile

Clinical utility of exome sequencing in hearing loss: a retrospective cohort study

Genome-wide evolution and function analysis of ALOG gene family in cotton

Correction: Identification and functional characteristics of a novel splice site variant in L1CAM caused X-linked hydrocephalus

Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition

Prediction of NR3C1 as a methylation marker for the prevention and treatment of gastric cancer in Rhizoma Atractylodis Macrocephalae based on machine learning algorithm and bioinformatics analysis

ZC3H18 regulates alternative splicing and related genes in cervical cancer

Constructing a neutrophil extracellular trap model based on machine learning to predict clinical outcomes and immune therapy responses in oral squamous cell carcinoma

Comprehensive analysis and validation of angiogenesis in vascular dementia from the perspective of diagnosis, prevention, and treatment

A lipid metabolism and lysosome-based risk signature for prognosis and immune response prediction in uterine corpus endometrial carcinoma

Mechanisms and recent advances in non-coding RNAs and RNA modifications in antiplatelet drug resistance

Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis

Geographical distribution of ALDH2 rs671 polymorphism in Chinese angina pectoris patients

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

Temporal regulation of genetic programs governing multiple cell death during myocardial ischemia-reperfusion injury

3D-cultured hADSCs-derived exosomes deliver circ_0011129 to synergistically attenuate skin photoaging

Integrating BERT pre-training with graph common neighbours for predicting ceRNA interactions

Validation of a genome-wide polygenic score for body mass index in South Asians

From reading to writing genomes: a new direction in ELSI

Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

Data report: transcriptome profiling of 13 tissues of Junmu No. 1 boars

Mining for gene-environment and gene-gene interactions: parametric and non-parametric tests for detecting variance quantitative trait loci

A de novo mutation in RAB11A is associated with neurodevelopmental disorder accompanied by variable multisystem abnormalities

Editorial: Mitochondria in metabolic reprogramming and immune activation: the key gene and therapeutic target