Frontiers in Genetics | Cancer Genetics and Oncogenomics

Correction

Published on 07 Oct 2025

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

in Cancer Genetics and Oncogenomics

Xiaoping Yang
Zuohui Yuan
Lingzhu Gou
Long Cheng
Zirui Wang
Pingfan Wu
Xiaochun Wang
Xueni Ma
Tiantian Ma
Yi Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1684479

1,421 views

Original Research

Published on 01 Oct 2025

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

in Cancer Genetics and Oncogenomics

Mingzhi Cai
Xinyang Nie
Fenglin Cai
Xiuding Yang
Weilin Sun
Rupeng Zhang
Han Liang
Yonglin Yang
Li Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1653700

2,675 views
1 citation

Methods

Published on 26 Sep 2025

CNAdjust: enhancing CNA calling accuracy through systematic baseline adjustment

in Cancer Genetics and Oncogenomics

Hangjia Zhao
Michael Baudis

Frontiers in Genetics

doi 10.3389/fgene.2025.1674138

2,730 views

Original Research

Published on 26 Sep 2025

Developing prognostic models for cholesterol-related genes linked with immune infiltration in prostate cancer

in Cancer Genetics and Oncogenomics

Jie Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1604113

2,778 views

Original Research

Published on 25 Sep 2025

MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma

in Cancer Genetics and Oncogenomics

Rong Qi
Chen Fang
Penghui Liu
Weiguo Gu
Chao Shi
Guohua Zhang
Feng Qiu

Frontiers in Genetics

doi 10.3389/fgene.2025.1615018

2,584 views

Original Research

Published on 24 Sep 2025

Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

in Cancer Genetics and Oncogenomics

Taorui Wang
Zijun Lai
Shengjun Tang
Lehang Lin
Mingjiao Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1654459

4,286 views

Original Research

Published on 22 Sep 2025

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

in Cancer Genetics and Oncogenomics

Jiaxuan Qin
Lijian Zhang
Bowen Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1543593

4,253 views

Original Research

Published on 22 Sep 2025

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

in Cancer Genetics and Oncogenomics

Xiucheng Jiang
Lan Shi
Mei Zhao
Cui Chen
Tao Tang
Simeng Ji
Bingbing Lv
Lihua Jia
Shuhan Duan
Jinyue Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1643229

2,490 views

Original Research

Published on 19 Sep 2025

The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

in Cancer Genetics and Oncogenomics

Tianhe Ling
Jiahui Wu
Ling Xiaohao

Frontiers in Genetics

doi 10.3389/fgene.2025.1606111

2,694 views

Original Research

Published on 18 Sep 2025

Identification of prognostic and cellular senescence gene E2F1 of papillary thyroid carcinoma through bioinformatics analyses and experimental verification

in Cancer Genetics and Oncogenomics

Bin Yu
Shu-Yan Zhao
Yun-Hua Zhu
Jun-Jie Luo
Ke Zheng
Bin-Jie Shen
Yi-Lin Shen
Huan-Xin Zhong

Frontiers in Genetics

doi 10.3389/fgene.2025.1605385

2,432 views

Original Research

Published on 17 Sep 2025

Panoramic analysis of the biological function and clinical value of SLC38A2 in human cancers: a study based on pan-cancer and single-cell analysis

in Cancer Genetics and Oncogenomics

Mao Liao
Yuqing Rao
Molan Li
Jiayang Guo
Kun Guo
Kaiyue Li
Rui Zheng
Yifan Liu
Qianyi Wang
Manni Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1658299

2,908 views

Original Research

Published on 17 Sep 2025

Bioinformatics-based identification of differentially expressed genes in endometrial carcinoma: implications for early diagnosis and prognostic stratification

in Cancer Genetics and Oncogenomics

Liang Gao
Donglan Yuan
Aihua Huang
Hua Qian

Frontiers in Genetics

doi 10.3389/fgene.2025.1631060

2,014 views

Original Research

Published on 16 Sep 2025

Identification and validation of three tumor suppressors associated with the immune response of acute myeloid leukemia

in Cancer Genetics and Oncogenomics

Yueyuan Pan
Guocai Wu
Chenchen Liu
Minggui Chen
Tian Xia
Yonghua Ma
Zhigang Yang
Ruiting Wen

Frontiers in Genetics

doi 10.3389/fgene.2025.1652142

3,564 views

Original Research

Published on 15 Sep 2025

Characterization of the phenotype and function of PRELP+ fibroblast subtype in liver metastatic colorectal cancer

in Cancer Genetics and Oncogenomics

Yuting Dai
Xingying Huang
Min Sun
Shiyu Zhang
Weiqiang Yu
Kongwang Hu
Qiang Wu
Qingfa Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1615259

3,496 views

Methods

Published on 15 Sep 2025

Construction of a novel prognostic model for gastric cancer based on pharmacokinetics-related genes and comprehensive prognostic analysis

in Cancer Genetics and Oncogenomics

Yu Zhang
Kai Jia
Yuntong Guo
Xiaole Ma
Tian Yao
Feng Wu
He Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1541401

2,233 views

Original Research

Published on 09 Sep 2025

Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition

in Cancer Genetics and Oncogenomics

Gizem Onder
Ozkan Ozdemir
Fulya Taylan
Cengiz Canpolat
Koray Yalcin
Fatih Erbey
Banu Oflaz Sozmen
Fikret Asarcikli
Turan Bayhan
Yunus Murat Akcabelen

Frontiers in Genetics

doi 10.3389/fgene.2025.1624306

4,376 views

Original Research

Published on 09 Sep 2025

ZC3H18 regulates alternative splicing and related genes in cervical cancer

in Cancer Genetics and Oncogenomics

Wenjuan Chen
Chenying Liu
Siyi Li
Xingyun Xie
Dan Hu
Yaobin Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1621238

2,429 views

Original Research

Published on 08 Sep 2025

A lipid metabolism and lysosome-based risk signature for prognosis and immune response prediction in uterine corpus endometrial carcinoma

in Cancer Genetics and Oncogenomics

Yuanyuan Zhu
Pusheng Yang
Shu Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1594682

2,635 views

Original Research

Published on 05 Sep 2025

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

in Cancer Genetics and Oncogenomics

Pengpeng Gui
Zhengyi Han
Zhenyu Yin
Peng Cao
Xin Zhou
Yan Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1593314

2,966 views

Brief Research Report

Published on 29 Aug 2025

Identification of oncofetal PIWI-interacting RNAs as potential prognostic biomarkers in non-small cell lung cancer

in Cancer Genetics and Oncogenomics

Michelle E. Pewarchuk
Vanessa G. P. Souza
David E. Cohn
Nikita Telkar
Greg L. Stewart
Katya H. Bénard
Patricia P. Reis
Victor D. Martinez
Wendy P. Robinson
Wan L. Lam

Frontiers in Genetics

doi 10.3389/fgene.2025.1611805

2,225 views
1 citation

Original Research

Published on 28 Aug 2025

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

in Cancer Genetics and Oncogenomics

Juan Lyu
Shanmei Lyu
Ying Qian
Yi Feng
Zhuan Zheng
Lihong Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1613631

2,363 views

Editorial

Published on 28 Aug 2025

Editorial: Emerging relevance of molecular profiling in global cancer research and management

in Cancer Genetics and Oncogenomics

Premila Leiphrakpam
Srijan Shukla
Chandrakanth Are

Frontiers in Genetics

doi 10.3389/fgene.2025.1679501

1,741 views

Original Research

Published on 25 Aug 2025

VCAM-1 predicts poor prognosis and modulates immune infiltration in gastric cancer: a TCGA-based bioinformatics study

in Cancer Genetics and Oncogenomics

Cheng Wu
Yungeng Liu
Chuanyuan Liu
Chuanfa Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1602929

2,354 views

Original Research

Published on 18 Aug 2025

The comparison of the prognostic value of different inflammation-related indicators in patients with oral squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Aoming Cheng
Kaixiong Wei
Qiaoshi Xu
Chong Wang
Bo Li
Huan Liu
Lirui Zhang
Hanchen Zhou
Yu Huang
Yiming Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1652603

2,256 views
1 citation

1,194 articles

articles

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

CNAdjust: enhancing CNA calling accuracy through systematic baseline adjustment

Developing prognostic models for cholesterol-related genes linked with immune infiltration in prostate cancer

MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma

Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

Identification of prognostic and cellular senescence gene E2F1 of papillary thyroid carcinoma through bioinformatics analyses and experimental verification

Panoramic analysis of the biological function and clinical value of SLC38A2 in human cancers: a study based on pan-cancer and single-cell analysis

Bioinformatics-based identification of differentially expressed genes in endometrial carcinoma: implications for early diagnosis and prognostic stratification

Identification and validation of three tumor suppressors associated with the immune response of acute myeloid leukemia

Characterization of the phenotype and function of PRELP+ fibroblast subtype in liver metastatic colorectal cancer

Construction of a novel prognostic model for gastric cancer based on pharmacokinetics-related genes and comprehensive prognostic analysis

Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition

ZC3H18 regulates alternative splicing and related genes in cervical cancer

A lipid metabolism and lysosome-based risk signature for prognosis and immune response prediction in uterine corpus endometrial carcinoma

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

Identification of oncofetal PIWI-interacting RNAs as potential prognostic biomarkers in non-small cell lung cancer

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

Editorial: Emerging relevance of molecular profiling in global cancer research and management

VCAM-1 predicts poor prognosis and modulates immune infiltration in gastric cancer: a TCGA-based bioinformatics study

The comparison of the prognostic value of different inflammation-related indicators in patients with oral squamous cell carcinoma