Frontiers in Genetics | Computational Genomics

Original Research

Published on 30 May 2025

Identification of biomarkers for the diagnosis of chronic kidney disease (CKD) with dilated cardiomyopathy (DCM) by bioinformatics analysis and machine learning

in Computational Genomics

Yuhang Liu
Yong Wang
Wenyang Nie
Zhen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1562891

3,972 views
1 citation

Editorial

Published on 29 May 2025

Editorial: Computational genomic and precision medicine

in Computational Genomics

Zeeshan Ahmed
Ramkumar Thirunavukarasu
Atlas Khan

Frontiers in Genetics

doi 10.3389/fgene.2025.1631668

2,376 views

Original Research

Published on 26 May 2025

Prediction of mild cognitive impairment using blood multi-omics data

in Computational Genomics

Daniel Frank Zhang
Cigdem Sevim Bayrak
Qi Zeng
Minghui Wang
Bin Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1552063

2,740 views

Methods

Published on 22 May 2025

stGuide advances label transfer in spatial transcriptomics through attention-based supervised graph representation learning

in Computational Genomics

Yupeng Xu
Hao Dai
Jinwang Feng
Keren Xu
Qiu Wang
Pingting Gao
Chunman Zuo

Frontiers in Genetics

doi 10.3389/fgene.2025.1566675

2,749 views
1 citation

Opinion

Published on 16 May 2025

From bites to bytes: understanding how and why individual malaria risk varies using artificial intelligence and causal inference

in Computational Genomics

Adèle Helena Ribeiro
Júlia M. P. Soler
Rodrigo M. Corder
Marcelo U. Ferreira
Dominik Heider

Frontiers in Genetics

doi 10.3389/fgene.2025.1599826

2,966 views
1 citation

Original Research

Published on 09 May 2025

Long-read sequencing reveals absence of 5mC in Ogataea parapolymorpha DL-1 genome and introduces telomere-to-telomere assembly

in Computational Genomics

Andrey Eremin
Alexander Sergeev
Arthur Kopylov
Vladimir Rodin
Daniil Malyshev
Tatiana Panova
Igor Polyakov
Maria Zvereva

Frontiers in Genetics

doi 10.3389/fgene.2025.1574332

2,230 views
1 citation

Technology and Code

Published on 02 May 2025

TCGADownloadHelper: simplifying TCGA data extraction and preprocessing

in Computational Genomics

Alexandra Anke Baumann
Olaf Wolkenhauer
Markus Wolfien

Frontiers in Genetics

doi 10.3389/fgene.2025.1569290

5,710 views
1 citation

Original Research

Published on 30 Apr 2025

Impact of nonsynonymous single nucleotide polymorphisms in PROCR gene on protein stability and thrombotic risk: a molecular dynamic approach

in Computational Genomics

Hytham Ahmed Abuagla
Khalid Mohamed Adam
Mohamed E. Elangeeb
Elsadig Mohamed Ahmed
Elshazali W. Ali
Ali M. Edris
Abubakr Ali Elamin MohamedAhmed
Elmoiz Idris Eltieb
Tarig Babikir Algak Khalid
Bahaeldin K. Elamin

Frontiers in Genetics

doi 10.3389/fgene.2025.1580993

2,151 views

Original Research

Published on 30 Apr 2025

High-precision lung cancer subtype diagnosis on imbalanced exosomal data via Exo-LCClassifier

in Computational Genomics

Siyu Zhan
Hao Yu
Shuang Liu
Ke Qin
Lu Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1583081

2,115 views
1 citation

Original Research

Published on 29 Apr 2025

Constructing ancestral recombination graphs through reinforcement learning

in Computational Genomics

Mélanie Raymond
Marie-Hélène Descary
Cédric Beaulac
Fabrice Larribe

Frontiers in Genetics

doi 10.3389/fgene.2025.1569358

2,581 views

Original Research

Published on 29 Apr 2025

Potential common mechanisms between primary Sjögren’s syndrome and Hashimoto’s thyroiditis: a public databases-based study

in Computational Genomics

Yanjun Lin
Shupin Tang
Yan Lin
Rihui Wang
Yifeng Xing
Zonghe Xu
Yan Li
Qingxia Fang
Wenwei Wei
Dong Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1520332

3,328 views
1 citation

Original Research

Published on 29 Apr 2025

The identification of a blood circular RNA signature that differentiates Chikungunya virus infection

in Computational Genomics

Xue Bai
Hanlin Yan
Guoxia Wen
Shaoxun Yuan
Wanjun Gu

Frontiers in Genetics

doi 10.3389/fgene.2025.1602177

2,664 views

Original Research

Published on 28 Apr 2025

Single-cell transcriptomic construction of fibroblast score for analysis of immune infiltration in primary and metastatic ovarian cancer

in Computational Genomics

Qian Guo
Hongmei Ding
Qinlin Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1549541

2,236 views

Original Research

Published on 28 Apr 2025

Shared genetic features inference among hypoxia-ischemia diseases in the presence of heterogenous omics data based on a novel risk assessment method

in Computational Genomics

Yifan Zhang
Jianfeng Liu
Zhuoma Basang
Qianxun Yang
Hongce Chen
Shuo Chen
Shaogang Li
Changgui Lei
Mingyan Fang
Huanhuan Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1587854

4,249 views
2 citations

Original Research

Published on 28 Apr 2025

Exploring WNT pathway dysregulation in serrated colorectal cancer for improved diagnostic and therapeutic strategies

in Computational Genomics

Fengzhi Zhu
Helen Hoi Ning Yan
Yin Tong
Yueliang Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1586867

2,400 views
1 citation

Original Research

Published on 24 Apr 2025

Key gene screening and diagnostic model establishment for acute type a aortic dissection

in Computational Genomics

Yue Pan
Zhiming Yu
Xiaoyu Qian
Xuesong Zhang
Qun Xue
Weizhang Xiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1586880

3,583 views

Original Research

Published on 24 Apr 2025

Integration of bulk RNA-seq and scRNA-seq reveals transcriptomic signatures associated with deep vein thrombosis

in Computational Genomics

Bao-ze Pan
Ming-jun Jiang
Li-ming Deng
Jie Chen
Xian-peng Dai
Zi-xuan Wu
Zhi-he Deng
Dong-yang Luo
Yang-yi-jing Wang
Dan Ning

Frontiers in Genetics

doi 10.3389/fgene.2025.1551879

4,227 views
1 citation

Methods

Published on 24 Apr 2025

MSI expresso: a software for determining MSI status and detecting MSI-related transcription events from RNA sequencing data

in Computational Genomics

Emmanuel Tubacher
Alexandre How-Kit
Mourad Sahbatou
Alex Duval
Victor Renault
Jean-François Deleuze

Frontiers in Genetics

doi 10.3389/fgene.2025.1523278

3,006 views

Original Research

Published on 16 Apr 2025

The potential crosstalk genes and molecular mechanisms between systemic lupus erythematosus and periodontitis

in Computational Genomics

Kai Zhao
Xiaolong Li
Qingmiao Zhu
Mengyu Zhu
Jinge Huang
Ting Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1527713

3,370 views
1 citation

Original Research

Published on 15 Apr 2025

Association prediction of lncRNAs and diseases using multiview graph convolution neural network

in Computational Genomics

Wei Zhang
Yifu Zeng
Xiaowen Xiang
Bihai Zhao
Sai Hu
Limiao Li
Xiaoyu Zhu
Lei Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1568270

2,590 views
1 citation

Original Research

Published on 14 Apr 2025

Engineering novel features for diabetes complication prediction using synthetic electronic health records

in Computational Genomics

Daniel Voskergian
Burcu Bakir-Gungor
Malik Yousef

Frontiers in Genetics

doi 10.3389/fgene.2025.1451290

2,839 views
2 citations

Original Research

Published on 14 Apr 2025

Explore potential immune-related targets of leeches in the treatment of type 2 diabetes based on network pharmacology and machine learning

in Computational Genomics

Tairan Hu
Zhaohui Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1554622

3,505 views
2 citations

Technology and Code

Published on 10 Apr 2025

Research on the optimization model of anti-breast cancer candidate drugs based on machine learning

in Computational Genomics

Zhou Dong
Hong Chen
Yuchen Yang
Hairong Hao

Frontiers in Genetics

doi 10.3389/fgene.2025.1523015

2,785 views
2 citations

Original Research

Published on 10 Apr 2025

Liver failure diagnosis: key diagnostic biomarkers discovery and bioinformatic validation

in Computational Genomics

Quan Ye
Kai Wang
Hong Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1554116

2,603 views

2,649 articles

articles

Identification of biomarkers for the diagnosis of chronic kidney disease (CKD) with dilated cardiomyopathy (DCM) by bioinformatics analysis and machine learning

Editorial: Computational genomic and precision medicine

Prediction of mild cognitive impairment using blood multi-omics data

stGuide advances label transfer in spatial transcriptomics through attention-based supervised graph representation learning

From bites to bytes: understanding how and why individual malaria risk varies using artificial intelligence and causal inference

Long-read sequencing reveals absence of 5mC in Ogataea parapolymorpha DL-1 genome and introduces telomere-to-telomere assembly

TCGADownloadHelper: simplifying TCGA data extraction and preprocessing

Impact of nonsynonymous single nucleotide polymorphisms in PROCR gene on protein stability and thrombotic risk: a molecular dynamic approach

High-precision lung cancer subtype diagnosis on imbalanced exosomal data via Exo-LCClassifier

Constructing ancestral recombination graphs through reinforcement learning

Potential common mechanisms between primary Sjögren’s syndrome and Hashimoto’s thyroiditis: a public databases-based study

The identification of a blood circular RNA signature that differentiates Chikungunya virus infection

Single-cell transcriptomic construction of fibroblast score for analysis of immune infiltration in primary and metastatic ovarian cancer

Shared genetic features inference among hypoxia-ischemia diseases in the presence of heterogenous omics data based on a novel risk assessment method

Exploring WNT pathway dysregulation in serrated colorectal cancer for improved diagnostic and therapeutic strategies

Key gene screening and diagnostic model establishment for acute type a aortic dissection

Integration of bulk RNA-seq and scRNA-seq reveals transcriptomic signatures associated with deep vein thrombosis

MSI expresso: a software for determining MSI status and detecting MSI-related transcription events from RNA sequencing data

The potential crosstalk genes and molecular mechanisms between systemic lupus erythematosus and periodontitis

Association prediction of lncRNAs and diseases using multiview graph convolution neural network

Engineering novel features for diabetes complication prediction using synthetic electronic health records

Explore potential immune-related targets of leeches in the treatment of type 2 diabetes based on network pharmacology and machine learning

Research on the optimization model of anti-breast cancer candidate drugs based on machine learning

Liver failure diagnosis: key diagnostic biomarkers discovery and bioinformatic validation