Original Research

Accepted on 17 Sep 2024

Polymorphic positions 349 and 725 of the autoimmunityprotective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties

in Antigen Presenting Cell Biology

Galateia Georgaki
Anastasia Mpakali
Myrto Trakada
Athanasios Papakyriakou
Efstratios Stratikos

Frontiers in Immunology

doi 10.3389/fimmu.2024.1415964

Original Research

Published on 28 Aug 2024

Internalization of therapeutic antibodies into dendritic cells as a risk factor for immunogenicity

in Antigen Presenting Cell Biology

Michel Siegel
Anna-Lena Bolender
Axel Ducret
Johannes Fraidling
Katharina Hartman
Cary M. Looney
Olivier Rohr
Timothy P. Hickling
Hubert Kettenberger
Martin Lechmann

Frontiers in Immunology

doi 10.3389/fimmu.2024.1406643

1,237 views
1 citation

Original Research

Published on 23 Aug 2024

Cellular stress increases DRIP production and MHC Class I antigen presentation

in Antigen Presenting Cell Biology

Natalie Pach
Michael Basler

Frontiers in Immunology

doi 10.3389/fimmu.2024.1445338

957 views

Original Research

Published on 20 Aug 2024

Development and characterization of dendritic cell internalization and activation assays contributing to the immunogenicity risk evaluation of biotherapeutics

in Antigen Presenting Cell Biology

Michel Siegel
Aman Padamsey
Anna-Lena Bolender
Patrick Hargreaves
Johannes Fraidling
Axel Ducret
Katharina Hartman
Cary M. Looney
Cristina Bertinetti-Lapatki
Olivier Rohr

Frontiers in Immunology

doi 10.3389/fimmu.2024.1406804

1,192 views
1 citation

Original Research

Published on 14 Aug 2024

Crucial role of dendritic cells in the generation of anti-tumor T-cell responses and immunogenic tumor microenvironment to suppress tumor development

in Antigen Presenting Cell Biology

Moe Tominaga
Tomofumi Uto
Tomohiro Fukaya
Shuya Mitoma
Dieter Riethmacher
Kunihiko Umekita
Yoshihiro Yamashita
Katsuaki Sato

Frontiers in Immunology

doi 10.3389/fimmu.2024.1200461

1,078 views

Mini Review

Published on 06 Aug 2024

Evaluating in vivo approaches for studying the roles of thymic DCs in T cell development in mice

in Antigen Presenting Cell Biology

Yi Wang
Mark M. W. Chong

Frontiers in Immunology

doi 10.3389/fimmu.2024.1451974

754 views

Original Research

Published on 26 Jun 2024

Gravidity influences distinct transcriptional profiles of maternal and fetal placental macrophages at term

in Antigen Presenting Cell Biology

Nida Ozarslan
Joshua F. Robinson
Sirirak Buarpung
M. Yvonne Kim
Megan R. Ansbro
Jason Akram
Dennis J. Montoya
Moses R. Kamya
Abel Kakuru
Grant Dorsey

Frontiers in Immunology

doi 10.3389/fimmu.2024.1384361

1,577 views

Original Research

Published on 24 Jun 2024

Anandamide modulation of monocyte-derived Langerhans cells: implications for immune homeostasis and skin inflammation

in Antigen Presenting Cell Biology

Zsófia Pénzes
Dorottya Horváth
Petra Molnár
Tünde Fekete
Kitti Pázmándi
Attila Bácsi
Attila Gábor Szöllősi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1423776

1,841 views

Original Research

Published on 06 Jun 2024

A pan-cancer single-cell transcriptional analysis of antigen-presenting cancer-associated fibroblasts in the tumor microenvironment

in Antigen Presenting Cell Biology

Juntao Chen
Renhui Chen
Jingang Huang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1372432

2,301 views

Original Research

Published on 15 May 2024

The cholera toxin B subunit induces trained immunity in dendritic cells and promotes CD8 T cell antitumor immunity

in Antigen Presenting Cell Biology

Araceli Tepale-Segura
Julián A. Gajón
Samira Muñoz-Cruz
Octavio Castro-Escamilla
Laura C. Bonifaz

Frontiers in Immunology

doi 10.3389/fimmu.2024.1362289

3,066 views

Original Research

Published on 08 May 2024

FASTMAP—a flexible and scalable immunopeptidomics pipeline for HLA- and antigen-specific T-cell epitope mapping based on artificial antigen-presenting cells

in Antigen Presenting Cell Biology

Luisa Weisbrod
Luigi Capriotti
Marco Hofmann
Valerie Spieler
Herbert Dersch
Bernd Voedisch
Peter Schmidt
Susanne Knake

Frontiers in Immunology

doi 10.3389/fimmu.2024.1386160

4,457 views

Original Research

Published on 05 Apr 2024

The functional role of L-fucose on dendritic cell function and polarization

in Antigen Presenting Cell Biology

Chase Burton
Amirreza Bitaraf
Kara Snyder
Chaomei Zhang
Sean J. Yoder
Dorina Avram
Dongliang Du
Xiaoqing Yu
Eric K. Lau

Frontiers in Immunology

doi 10.3389/fimmu.2024.1353570

2,078 views

Original Research

Published on 25 Mar 2024

Differences in F pocket impact on HLA I genetic associations with autoimmune diabetes

in Antigen Presenting Cell Biology

Xu Ren
A. W. Peshala Amarajeewa
M. D. Tharushika Jayasinghe
Malgorzata A. Garstka

Frontiers in Immunology

doi 10.3389/fimmu.2024.1342335

1,938 views

Original Research

Published on 20 Mar 2024

The antibodies 3D12 and 4D12 recognise distinct epitopes and conformations of HLA-E

in Antigen Presenting Cell Biology

Simon Brackenridge
Nessy John
Klaus Früh
Persephone Borrow
Andrew J. McMichael

Frontiers in Immunology

doi 10.3389/fimmu.2024.1329032

2,237 views
2 citations

Original Research

Published on 16 Jan 2024

Evaluating NetMHCpan performance on non-European HLA alleles not present in training data

in Antigen Presenting Cell Biology

Thomas Karl Atkins
Arnav Solanki
George Vasmatzis
James Cornette
Marc Riedel

Frontiers in Immunology

doi 10.3389/fimmu.2023.1288105

2,548 views

Original Research

Published on 11 Jan 2024

Myeloid cell MHC I expression drives CD8+ T cell activation in nonalcoholic steatohepatitis

in Antigen Presenting Cell Biology

Victoria R. Adams
Leonard B. Collins
Taufika Islam Williams
Jennifer Holmes
Paul Hess
Hannah M. Atkins
Grace Scheidemantle
Xiaojing Liu
Mareca Lodge
Aaron J. Johnson

Frontiers in Immunology

doi 10.3389/fimmu.2023.1302006

2,756 views
3 citations

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Articles

Polymorphic positions 349 and 725 of the autoimmunityprotective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties

Internalization of therapeutic antibodies into dendritic cells as a risk factor for immunogenicity

Cellular stress increases DRIP production and MHC Class I antigen presentation

Development and characterization of dendritic cell internalization and activation assays contributing to the immunogenicity risk evaluation of biotherapeutics

Crucial role of dendritic cells in the generation of anti-tumor T-cell responses and immunogenic tumor microenvironment to suppress tumor development

Evaluating in vivo approaches for studying the roles of thymic DCs in T cell development in mice

Gravidity influences distinct transcriptional profiles of maternal and fetal placental macrophages at term

Anandamide modulation of monocyte-derived Langerhans cells: implications for immune homeostasis and skin inflammation

A pan-cancer single-cell transcriptional analysis of antigen-presenting cancer-associated fibroblasts in the tumor microenvironment

The cholera toxin B subunit induces trained immunity in dendritic cells and promotes CD8 T cell antitumor immunity

FASTMAP—a flexible and scalable immunopeptidomics pipeline for HLA- and antigen-specific T-cell epitope mapping based on artificial antigen-presenting cells

The functional role of L-fucose on dendritic cell function and polarization

Differences in F pocket impact on HLA I genetic associations with autoimmune diabetes

The antibodies 3D12 and 4D12 recognise distinct epitopes and conformations of HLA-E

Evaluating NetMHCpan performance on non-European HLA alleles not present in training data

Myeloid cell MHC I expression drives CD8+ T cell activation in nonalcoholic steatohepatitis