Frontiers in Immunology | Parasite Immunology

Original Research

Accepted on 02 Jun 2025

Toxoplasma gondii virulence in mice is determined by the pseudokinase ROP5B and countered by an IRG-GBP protein interplay

in Parasite Immunology

Shishir Singh
Mateo Murillo-León
Aura Maria Bastidas Quintero
Florence Melbert
Klaus Pfeffer
Daniel Degrandi
Tobias Steinfeldt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593785

Original Research

Accepted on 02 Jun 2025

Splenic macrophage functional profile in the immunopathogenesis of canine visceral leishmaniasis

in Parasite Immunology

Tainã Luís De Souza
Marta De Almeida Santiago
Francini Neves Ribeiro
Fabiano Borges Figueiredo
Artur Augusto Velho Mendes Junior
Rodrigo Caldas Menezes
Renato Porrozzi
Fernanda Nazaré Morgado

Frontiers in Immunology

doi 10.3389/fimmu.2025.1617751

Original Research

Accepted on 28 May 2025

Dual single-cell and bulk RNA sequencing reveal transcriptional profiles underlying heterogenous host-parasite interactions in human peripheral blood mononuclear cells

in Parasite Immunology

Praveena R G Chandrasegaran
Barbara Shih
Musa Hassan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1582645

116 views

Original Research

Accepted on 27 May 2025

Vaccine-induced responses to R21/Matrix-M -an analysis of samples from a phase 1b age de-escalation, dose-escalation trial

in Parasite Immunology

Caroline Bundi
Duncan Bellamy
Elizabeth Kibwana
Lydia Nyamako
Rodney Ogwang
Kelvias Keter
Domtila KIMANI
Ahmed M Salman
Samuel Provstgaard-Morys
Lisa Stockdale

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620366

216 views

Original Research

Published on 27 May 2025

Emu-miR-10a-5p in Echinococcus multilocularis-derived-extracellular vesicles alleviates airway inflammation in mice with allergic asthma by inhibiting macrophage M2a polarization through LIF-mediated JAK1–STAT3 signaling

in Parasite Immunology

Yunzhuo Xin
Rou Wen
Dong Song
Jing Xiao
Xiaoping Gao
Mei Yin
Yanli Bai
Jie Wang
Xiangyu Zhou
Jiaqing Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1577349

513 views

General Commentary

Accepted on 23 May 2025

Commentary: Induction of hepatic fibrosis in mice with schistosomiasis by extracellular microRNA-30 derived from Schistosoma japonicum eggs

in Parasite Immunology

Haoran Zhong
Yamei Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604905

142 views

Original Research

Accepted on 22 May 2025

Dual Roles of Anisakis pegreffii Proteins in Macrophage Immune Dynamics

in Parasite Immunology

Min-hao Zeng
Sarah Alsobaie
Xiao-Xu Wang
Shan Li
Fahad M. Aldakheel
Mourad A. M. Aboul-Soud
Wei-Bin Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595093

159 views

Original Research

Published on 20 May 2025

Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis

in Parasite Immunology

Dongmei Yuan
Hanxiao Qin
Zeying Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595702

546 views

Original Research

Accepted on 19 May 2025

Interferons and Toxoplasma gondii shape PD-L1 regulation in retinal barrier cells: The critical role of proteases

in Parasite Immunology

Benjamin GEILLER
Camila Cevallos
Iuliia Tsybenko
Lydia Arnoux
Marie-Paule Felder-Schmittbuhl
Alexander W Pfaff

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607247

156 views

Case Report

Accepted on 19 May 2025

Disseminated Leishmaniasis and Rheumatoid Arthritis: Navigating a Clinical Conundrum

in Parasite Immunology

Endrit Shahini
Donatello Marziliano
Francesco Losito
Marianna Zappimbulso
Cavalcanti Elisabetta
Raffaele Armentano
Fabio Fucilli
Raffaele Cozzolongo
Giuseppe Ingravallo
Fabrizio Pappagallo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599381

230 views

Editorial

Published on 08 May 2025

Editorial: Neutrophil extracellular traps (NETs) triggered by helminths and protozoan parasites

in Parasite Immunology

Rafael M. Mariante
Tamara Muñoz-Caro
Elvira M. Saraiva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613886

846 views

Original Research

Published on 05 May 2025

Self and parasite-derived peptides selected upon DERAA-bearing HLA-DRB1 alleles activate CD4+ T cells from Chagas cardiomyopathy patients and are associated with ventricular dysfunction

in Parasite Immunology

Thaiany G. Souza-Silva
Eula G. A. Neves
Andrea Teixeira-Carvalho
Amanda Braga Figueiredo
Katia Luciano Pereira Morais
Juliana Apostólico
Hélcio Rodrigues
Jorge Kalil
Maria Aparecida Juliano
Luiz Juliano

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527115

1,218 views

Original Research

Published on 05 May 2025

Blue light-emitting diode phototherapy presents in vitro efficacy against distinct Leishmania species and is therapeutic against tegumentary leishmaniasis in BALB/c mice

in Parasite Immunology

Breno Luiz Pimenta
Daniela Pagliara Lage
Camila Simões de Freitas
Danniele Luciana Vale
Karolina Oliveira de Melo Falcão
Saulo Samuel Gonçalves Dias
Raquel Soares Bandeira Câmara
Isabela Amorim Gonçalves Pereira
Ana Luiza Silva
Lauro de Assis Duarte Júnior

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554051

977 views

Original Research

Published on 05 May 2025

Protective effects of Nippostrongylus brasiliensis-derived uridine via the apical sodium-dependent bile acid transporter in a mouse model of TNBS-induced inflammatory bowel disease

in Parasite Immunology

Caiyi Yuan
Qiang Wang
Yuying Chen
Xin Ding
Qiang Zhang
Jiakai Yao
Bei Zhang
Yang Dai
Hongxia Bai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600838

982 views

Original Research

Published on 01 May 2025

Spleen and peripheral blood immunopathology in an outbred model of adult-stage murine schistosomiasis

in Parasite Immunology

Thomas T. Schulze
Andrew J. Neville
Evie G. Ehrhorn
Sarah A. Alsuleiman
Jonathan L. Vennerstrom
Paul H. Davis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527129

1,067 views

Original Research

Published on 28 Apr 2025

Different responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models

in Parasite Immunology

Ana Carolina Leão
Maria Jose Villar
Rakesh Adhikari
Cristina Poveda
Leroy Versteeg
Gregório Almeida
Peter J. Hotez
Maria Elena Bottazzi
Kathryn M. Jones

Frontiers in Immunology

doi 10.3389/fimmu.2025.1487317

1,262 views