Frontiers in Neurology | Experimental Therapeutics

Study Protocol

Accepted on 16 Dec 2025

Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Perioperative Anxiety in Patients Undergoing Radical Mastectomy: Study Protocol for a Randomized Controlled Clinical Trial

in Experimental Therapeutics

Jiayi Tang
Ming Yao
Tong Wu
Huadong Ni

Frontiers in Neurology

Systematic Review

Published on 12 Dec 2025

Acupuncture combined with antidepressants for mild-to-moderate depressive disorders: a systematic review with meta-analysis and trial sequential analysis

in Experimental Therapeutics

Yingdong Wang
Yi Yu
Shike Zhang
Qiang Xi
Jiwen Qiu
Xinju Li
Mingxing Zhang
Yi Guo

Frontiers in Neurology

doi 10.3389/fneur.2025.1636589

396 views

Systematic Review

Published on 12 Dec 2025

Acupuncture combined with repetitive transcranial magnetic stimulation for the treatment of post-stroke cognitive impairment: a systematic review and meta-analysis with trial sequential analysis

in Experimental Therapeutics

Xiaomeng Zhang
Jie Wang
Wen Pan
Jin Sun
Mingna He
Qinyun Wang
Peiyang Sun

Frontiers in Neurology

doi 10.3389/fneur.2025.1663452

350 views

Review

Published on 10 Dec 2025

Mechanism of the analgesic effect of electroacupuncture on bone cancer pain through the neuro-immune system: progress based on animal experiments

in Experimental Therapeutics

Pengfei Qi
Mingyuan Zhou
Wenqing Han
Hongxiang Li
Lu Min
Jiaxin Li
Zhongren Sun
Hongna Yin

Frontiers in Neurology

doi 10.3389/fneur.2025.1693978

515 views

Review

Published on 10 Dec 2025

A narrative review of neuroprotective effects of remifentanil: from basic research to clinical practice

in Experimental Therapeutics

Xun Jiang
Meirong Wu
Chenghui Yan
Jia Liu

Frontiers in Neurology

doi 10.3389/fneur.2025.1707972

416 views

Correction

Published on 09 Dec 2025

Correction: Clinical efficacy and safety of acupuncture versus Western medicine for insomnia: a systematic review and meta-analysis

in Experimental Therapeutics

Jun Ma
Meng Peng
Xue-Jiao Xu

Frontiers in Neurology

doi 10.3389/fneur.2025.1750057

171 views

Perspective

Published on 09 Dec 2025

The role of neuro-supportive substances of natural origin in neurological conditions—A literature-based formulators' perspective

in Experimental Therapeutics

Roy van Brummelen
Anna C. van Brummelen

Frontiers in Neurology

doi 10.3389/fneur.2025.1647092

290 views

Systematic Review

Accepted on 08 Dec 2025

Efficacy and safety of electroacupuncture in the treatment of Post-stroke cognitive impairment: a systematic review and meta-analysis

in Experimental Therapeutics

Jiayi Zhu
Xihan Ying
Tianqi Huang
Yufei Zhang
Kelin He
RUIJIE MA

Frontiers in Neurology

Review

Accepted on 08 Dec 2025

Research Progress on Transcranial Direct Current Stimulation for Improving Muscle Strength: A Narrative Review

in Experimental Therapeutics

Yiguang Zhang
Yi Zhang
Yu Song
Huaduo Wu
Xin Gao
Yumo Dong
Ning Jiang

Frontiers in Neurology

Review

Accepted on 08 Dec 2025

Recent Advances and Evolving Strategies in the Treatment of Lumbar Disc Herniation

in Experimental Therapeutics

Yun Tong
Lanying Yu
Kaifeng Luo
Xiong Yan
Ming Chen
Libin Wang

Frontiers in Neurology

251 views

Original Research

Accepted on 05 Dec 2025

A comparison between robot-assisted minimally invasive surgery and conventional craniotomy for intracerebral hemorrhage: efficiency, complications and outcomes

in Experimental Therapeutics

Mingxiao Li
Yufei Gao
Ce Wang
Aimin Li
Ziyi Liu
Yulian Zhang
Lijun Yang
Yanbing Yu
Xueke Zhen

Frontiers in Neurology

105 views

Clinical Trial

Published on 04 Dec 2025

The effectiveness of Zhi-Shi plaster acupoint therapy combined with lactulose in the treatment of geriatrics functional constipation: a randomized controlled trial

in Experimental Therapeutics

Ying Wang
XiXia Zhang
XueFei Ding
Hui Li
JunQuan Xia
MengYan Zhou
YongZhi Hua
KeXuan Wu
LongShu Zhang
LiRong Zhou

Frontiers in Neurology

doi 10.3389/fneur.2025.1580163

401 views

Study Protocol

Published on 01 Dec 2025

Efficacy and safety of combination of frankincense and botulinum toxin in the treatment of blepharospasm: a protocol for a single-centre, open-label, randomized, controlled trial

in Experimental Therapeutics

Shiyuan Gong
Yuhan Luo
Jiana Zhang
Feiwen Huang
Zhengkun Yang
Yue Zhang
Zilin Ou
Zhicong Yan
Weixi Zhang
Qian Zhou

Frontiers in Neurology

doi 10.3389/fneur.2025.1693914

368 views

Original Research

Published on 28 Nov 2025

Prediction of acupuncture efficacy in acute ischemic stroke constructing a clinical-radiomics multimodal model

in Experimental Therapeutics

Lijuan Zhao
Ziguang Huang
Baoying Zhao
Ran An
Yanyan Cheng

Frontiers in Neurology

doi 10.3389/fneur.2025.1682842

438 views

Original Research

Accepted on 27 Nov 2025

Constructing and Applying a Tiered Family Engagement Strategy for Managing Neurogenic Bowel Dysfunction in TSCI Patients

in Experimental Therapeutics

Hongyan Li
Zhaoxuan Wang
Jia Ding
Qian Wang
Ruiling Wang

Frontiers in Neurology

Systematic Review

Accepted on 25 Nov 2025

Acupuncture for Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy: A Systematic Review and Meta-analysis

in Experimental Therapeutics

Zining Guo
Zhang Jiewen
Run Lin
Liying Wang
Lu Zhang
Xiaorong Tang
Wenhao Liu
Shaoyang Cui
Nenggui Xu

Frontiers in Neurology

112 views

Study Protocol

Accepted on 18 Nov 2025

Comparative Effectiveness and Safety of Herbal Medicine Therapy for Low Back Pain and Radiculopathy Caused by Lumbar Intervertebral Disc Herniation: A Study Protocol for a Pragmatic Randomized Controlled Trial

in Experimental Therapeutics

Jung-Hyun Kim
Yoon Jae Lee
In-Huyk Ha
Won-Suk Sung
Eun-Jung Kim
Yeoncheol Park
Yonghyeon Baek
Sang Soo Nam
Byung-Kwan Seo

Frontiers in Neurology

140 views

Original Research

Published on 18 Nov 2025

Clinical application of unilateral biportal endoscopic lumbar interbody fusion in lumbar degenerative diseases: a multi-center study

in Experimental Therapeutics

Yunsheng Chen
Jian Wu
Qiaoxin Li
Yaohong Wu
Canhua Xu
Rongchun Chen
Jiangyou Shi
Liping Liu
Linbo Sun
Jun Xiong

Frontiers in Neurology

doi 10.3389/fneur.2025.1673110

712 views

Systematic Review

Published on 14 Nov 2025

Clinical efficacy and safety of acupuncture versus Western medicine for insomnia: a systematic review and meta-analysis

in Experimental Therapeutics

Jun Ma
Meng Peng
Xue-Jiao Xu

Frontiers in Neurology

doi 10.3389/fneur.2025.1589535

2,050 views

Systematic Review

Published on 12 Nov 2025

Efficacy of acupuncture versus sham acupuncture on generalized anxiety disorder: a meta-analysis of randomized controlled trials

in Experimental Therapeutics

Hongzhan Jiang
Ruiqing Ma
Yaxin Huang
Xuejing Li
Yufang Hao

Frontiers in Neurology

doi 10.3389/fneur.2025.1682400

1,281 views

Systematic Review

Published on 07 Nov 2025

Acupuncture improves blood–brain barrier integrity through multi-targeted mechanisms: a preclinical meta-analysis

in Experimental Therapeutics

Kexing Zhang
Ying Liang
Yinxin Wang
Tong Yin
Kangwen Ming

Frontiers in Neurology

doi 10.3389/fneur.2025.1648117

1,315 views

Original Research

Published on 05 Nov 2025

Synergistic benefits of melatonin and therapeutic exercise as a unified strategy for managing stroke and doxorubicin-induced cardiotoxicity

in Experimental Therapeutics

Sookyoung Park
Zeeshan Ahmad Khan
Yunkyung Hong
Jinhee Shin
Tserentogtokh Lkhagvasuren
Seunghoon Lee
Yonggeun Hong

Frontiers in Neurology

doi 10.3389/fneur.2025.1567263

942 views

Systematic Review

Published on 03 Nov 2025

The efficacy and safety of acupuncture for Parkinson’s disease insomnia: a systematic review and meta-analysis

in Experimental Therapeutics

Yujie Gu
Yue Liang
Hui Han
Huichao Yin
Zuncheng Zheng

Frontiers in Neurology

doi 10.3389/fneur.2025.1697481

1,189 views

Original Research

Published on 29 Oct 2025

Herbal medicine and acupuncture for mild cognitive impairment: a retrospective study of 2,242 for older adults in Republic of Korea

in Experimental Therapeutics

Hyo-Weon Suh
Jae Hwan Lim
Jin-woo Suh
Chan Park
Yong-Sin Park
Sun-Yong Chung

Frontiers in Neurology

doi 10.3389/fneur.2025.1628794

1,240 views

307 articles

articles

Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Perioperative Anxiety in Patients Undergoing Radical Mastectomy: Study Protocol for a Randomized Controlled Clinical Trial

Acupuncture combined with antidepressants for mild-to-moderate depressive disorders: a systematic review with meta-analysis and trial sequential analysis

Acupuncture combined with repetitive transcranial magnetic stimulation for the treatment of post-stroke cognitive impairment: a systematic review and meta-analysis with trial sequential analysis

Mechanism of the analgesic effect of electroacupuncture on bone cancer pain through the neuro-immune system: progress based on animal experiments

A narrative review of neuroprotective effects of remifentanil: from basic research to clinical practice

Correction: Clinical efficacy and safety of acupuncture versus Western medicine for insomnia: a systematic review and meta-analysis

The role of neuro-supportive substances of natural origin in neurological conditions—A literature-based formulators' perspective

Efficacy and safety of electroacupuncture in the treatment of Post-stroke cognitive impairment: a systematic review and meta-analysis

Research Progress on Transcranial Direct Current Stimulation for Improving Muscle Strength: A Narrative Review

Recent Advances and Evolving Strategies in the Treatment of Lumbar Disc Herniation

A comparison between robot-assisted minimally invasive surgery and conventional craniotomy for intracerebral hemorrhage: efficiency, complications and outcomes

The effectiveness of Zhi-Shi plaster acupoint therapy combined with lactulose in the treatment of geriatrics functional constipation: a randomized controlled trial

Efficacy and safety of combination of frankincense and botulinum toxin in the treatment of blepharospasm: a protocol for a single-centre, open-label, randomized, controlled trial

Prediction of acupuncture efficacy in acute ischemic stroke constructing a clinical-radiomics multimodal model

Constructing and Applying a Tiered Family Engagement Strategy for Managing Neurogenic Bowel Dysfunction in TSCI Patients

Acupuncture for Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy: A Systematic Review and Meta-analysis

Comparative Effectiveness and Safety of Herbal Medicine Therapy for Low Back Pain and Radiculopathy Caused by Lumbar Intervertebral Disc Herniation: A Study Protocol for a Pragmatic Randomized Controlled Trial

Clinical application of unilateral biportal endoscopic lumbar interbody fusion in lumbar degenerative diseases: a multi-center study

Clinical efficacy and safety of acupuncture versus Western medicine for insomnia: a systematic review and meta-analysis

Efficacy of acupuncture versus sham acupuncture on generalized anxiety disorder: a meta-analysis of randomized controlled trials

Acupuncture improves blood–brain barrier integrity through multi-targeted mechanisms: a preclinical meta-analysis

Synergistic benefits of melatonin and therapeutic exercise as a unified strategy for managing stroke and doxorubicin-induced cardiotoxicity

The efficacy and safety of acupuncture for Parkinson’s disease insomnia: a systematic review and meta-analysis

Herbal medicine and acupuncture for mild cognitive impairment: a retrospective study of 2,242 for older adults in Republic of Korea