Frontiers in Neurology | Neurological Biomarkers

Original Research

Published on 06 Feb 2026

Protein biomarker discovery in neural tissue: a comparative analysis of immunoassay and colloidal gold lateral flow assay method

in Neurological Biomarkers

Zhengang Su
Kai Huang
Zi Wang

Frontiers in Neurology

doi 10.3389/fneur.2026.1686630

315 views

Original Research

Accepted on 02 Feb 2026

Associations between Blood glucose - lipid levels and post-intravenous thrombolysis outcomes in stroke patients: A retrospective study utilizing logistic regression analysis

in Neurological Biomarkers

Liu He
Rong Li
Yan Liu
Xin Tan
Lei Wang
Xi Zhu
Qiang Zhou
Zhiyong Yang
Hua Liu

Frontiers in Neurology

199 views

Systematic Review

Published on 29 Jan 2026

Meta-analysis for the associations of serum C-reactive protein with delirium risk

in Neurological Biomarkers

Qi-xian Liang
Xiao-li Tan
Zhi-wei Huang
Shuai Chen
Ye-zhao Li
Zhao-yin Fu

Frontiers in Neurology

doi 10.3389/fneur.2026.1728476

338 views

Original Research

Accepted on 27 Jan 2026

The Value of Peripheral Blood PLR, Lp-PLA2, MHR, SII, and HCY in Assessing the Rupture Risk of Small and Medium-Sized Intracranial Aneurysms

in Neurological Biomarkers

Chaojun Yan
Xinyu Lu

Frontiers in Neurology

Original Research

Accepted on 26 Jan 2026

Pre-procedural Vitamin D Deficiency and Poor Prognosis Post-Thrombectomy in Patients with Acute Anterior Circulation Large Vessel Occlusion: A Retrospective Cohort Study

in Neurological Biomarkers

Pan Xu
Kewei Liu
Jinyu Li
Wuying Li
Weihua Deng
Huameng Huang
Xing Li

Frontiers in Neurology

Original Research

Published on 20 Jan 2026

Associations of eosinophil-to-monocyte ratio and C-reactive protein-to-high-density lipoprotein cholesterol ratio with early neurological deterioration after thrombolysis in acute ischemic stroke

in Neurological Biomarkers

Guohua He
Guilan Xu
Yanqiao Xiao
Zhen Wang
Yachun Yu

Frontiers in Neurology

doi 10.3389/fneur.2025.1687536

737 views

Original Research

Published on 14 Jan 2026

Serum P2X7 as a prognostic biomarker in acute supratentorial intracerebral hemorrhage: a two-center observational study

in Neurological Biomarkers

Xinle Chen
Hao Shan
Tiancheng Lu
Boren Zheng
Xiaoqiao Dong
Yulin Sun
Xiaojun Zhong
Guozheng Ying

Frontiers in Neurology

doi 10.3389/fneur.2025.1696189

561 views

Original Research

Published on 12 Jan 2026

The prognostic significance of uric acid to albumin ratio in patients with aneurysmal subarachnoid hemorrhage following surgical clipping or endovascular interventions: insights from a large cohort study

in Neurological Biomarkers

Xielin Tang
Xiaoyi Wang
Bingcheng Zhu
Liangxue Zhou
Xiaolin Chen

Frontiers in Neurology

doi 10.3389/fneur.2025.1648805

488 views

Correction

Published on 12 Jan 2026

Correction: Inflammatory biomarkers in cerebral venous thrombosis versus ischemic stroke: a network meta-analysis

in Neurological Biomarkers

Xinlong Shen
Ling Chen
Liling Shen
Shuling Chen
Shuwen Mu
Li Chen
Shousen Wang
Ziqi Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1769992

833 views

Original Research

Published on 12 Jan 2026

Prognostic significance of the C-reactive protein–albumin–lymphocyte index and the pan-immune-inflammation value in ischemic and hemorrhagic stroke: a comparative analysis of subtypes

in Neurological Biomarkers

Canan Şahin
Yahya Şahin

Frontiers in Neurology

doi 10.3389/fneur.2025.1724077

560 views

Original Research

Published on 12 Jan 2026

Reduced global BOLD-CSF coupling in chronic kidney disease-related cognitive impairment: a resting-state functional MRI study

in Neurological Biomarkers

Bingkui Yang
Feng Cui
Kexin Li
Yuxuan Zhu
Yu Zhang
Luping Zhang
Zhiqiang Yan
Ping Jin

Frontiers in Neurology

doi 10.3389/fneur.2025.1738198

708 views

Study Protocol

Published on 09 Jan 2026

Biomarker role in assessing imaging needs for mild cranial trauma (BRAIN-CT): study protocol for a single-center, randomized controlled trial

in Neurological Biomarkers

Ali Tfaily
Ariana Chacon
Tianwen Ma
Jonathan Ratcliff
Randi Smith
Hassan Saad
Andrew Reisner
David Gimbel
Kevin Wang
Firas Kobeissy

Frontiers in Neurology

doi 10.3389/fneur.2025.1692163

843 views

Original Research

Published on 07 Jan 2026

Association between advanced lung cancer inflammation index levels and ischemic stroke in patients with atrial fibrillation: a propensity score-matching analysis

in Neurological Biomarkers

Ying Li
Xuelin Lu
Zuoan Qin
Jiangbiao Yu

Frontiers in Neurology

doi 10.3389/fneur.2025.1652042

690 views

Original Research

Published on 02 Jan 2026

Development of a clinical prediction model for inflammatory biomarkers and enlarged basal ganglia perivascular spaces using SHAP analysis: feature selection and model interpretation

in Neurological Biomarkers

Jiayu Lv
Dewang Gao
Wen Yong
Wenlong Yu
Lu Wang
Shangjia Ma
Hua Li
Shuaiqiang Zhang
Zi Guo
Hao Yan

Frontiers in Neurology

doi 10.3389/fneur.2025.1665841

631 views

Original Research

Published on 17 Dec 2025

Admission monocyte-to-albumin ratio predicts 3-month functional outcomes after acute ischemic stroke: a retrospective cohort study

in Neurological Biomarkers

Huizhen Lu
Chuanliu Wang
Ming Yang
Yuanshao Lin
Weifeng Jiang

Frontiers in Neurology

doi 10.3389/fneur.2025.1705544

848 views

Original Research

Published on 11 Dec 2025

Machine learning–driven risk prediction of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage using peripheral inflammatory markers

in Neurological Biomarkers

Yuanyuan Liu
Chengchen Li
Honglin Wang

Frontiers in Neurology

doi 10.3389/fneur.2025.1713341

979 views

Brief Research Report

Published on 08 Dec 2025

Longitudinal association of retinal morphology and white matter progression in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations

in Neurological Biomarkers

Henok Getahun
Rajendra S. Apte
Wilson X. Wang
Vivian Chen
Mae Gordon
Julia Huecker
John P. Atkinson
M. Kathryn Liszewski
Slim Fellah
Serguei V. Astafiev

Frontiers in Neurology

doi 10.3389/fneur.2025.1724411

905 views

Original Research

Published on 01 Dec 2025

HMOX1 mRNA combined with early imaging parameters for predicting the prognosis of hypertensive cerebral hemorrhage patients undergoing conservative treatment

in Neurological Biomarkers

Jinjiang Dong
Xiaofeng Ye
Popo Wang
Qijun Ye
Deqing Peng

Frontiers in Neurology

doi 10.3389/fneur.2025.1657188

1,009 views

Systematic Review

Published on 26 Nov 2025

Inflammatory biomarkers in cerebral venous thrombosis versus ischemic stroke: a network meta-analysis

in Neurological Biomarkers

Xinlong Shen
Ling Chen
Liling Shen
Shuling Chen
Shuwen Mu
Li Chen
Shousen Wang
Ziqi Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1634369

1,406 views

Original Research

Published on 24 Nov 2025

Impact of PCSK9 inhibitor on T lymphocyte subsets and cytokines in patients with acute ischemic stroke: an exploratory analysis of a randomized clinical trial

in Neurological Biomarkers

Jiahui Liu
Chao Han
Xiaofei Ji
Hua Cao
Shuna Chen
Chengcheng Tan
Xinqing Hao
Yuki Joyama
Wei Zou
Ying Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1688553

1,121 views

Correction

Published on 24 Nov 2025

Correction: Identification of stroke biomarkers using proteomic profiling of extracellular vesicles derived from human blood: a preliminary study

in Neurological Biomarkers

Tae Yeon Kim
Jae Yeon Park
Yun Seo Cho
Dong Hyuk Youn
Sung Woo Han
Harry Jung
Yong-Jun Cho
In cheol Jeong
Jin Pyeong Jeon
Kangeun Ko

Frontiers in Neurology

doi 10.3389/fneur.2025.1736367

611 views

Original Research

Published on 19 Nov 2025

Association between the systemic inflammatory response index and acute ischemic stroke in young people

in Neurological Biomarkers

He Wang
Huimin Qiao
Xiangjian Zhang
Peng Wu
Yuxiao Gao
Xin Liu
Haisen An
Wanyue Ge
Meiling Song
Yatong Wang

Frontiers in Neurology

doi 10.3389/fneur.2025.1644963

1,363 views

Review

Published on 18 Nov 2025

Receptor-mediated mitophagy: a new target of neurodegenerative diseases

in Neurological Biomarkers

Junlan Yang
Fuquan Yang
Guiyan Chen
Ming Liu
Shiqing Yuan
Tian-e Zhang

Frontiers in Neurology

doi 10.3389/fneur.2025.1665315

2,176 views
1 citation

Review

Published on 06 Nov 2025

Peripheral blood immune inflammatory markers in neuromyelitis optica spectrum disorders

in Neurological Biomarkers

Bin Wu
Fangzheng Cao
Mengying Mao
Xiaoli Gong
Bin Xu

Frontiers in Neurology

doi 10.3389/fneur.2025.1690767

1,867 views
1 citation

458 articles

articles

Protein biomarker discovery in neural tissue: a comparative analysis of immunoassay and colloidal gold lateral flow assay method

Associations between Blood glucose - lipid levels and post-intravenous thrombolysis outcomes in stroke patients: A retrospective study utilizing logistic regression analysis

Meta-analysis for the associations of serum C-reactive protein with delirium risk

The Value of Peripheral Blood PLR, Lp-PLA2, MHR, SII, and HCY in Assessing the Rupture Risk of Small and Medium-Sized Intracranial Aneurysms

Pre-procedural Vitamin D Deficiency and Poor Prognosis Post-Thrombectomy in Patients with Acute Anterior Circulation Large Vessel Occlusion: A Retrospective Cohort Study

Associations of eosinophil-to-monocyte ratio and C-reactive protein-to-high-density lipoprotein cholesterol ratio with early neurological deterioration after thrombolysis in acute ischemic stroke

Serum P2X7 as a prognostic biomarker in acute supratentorial intracerebral hemorrhage: a two-center observational study

The prognostic significance of uric acid to albumin ratio in patients with aneurysmal subarachnoid hemorrhage following surgical clipping or endovascular interventions: insights from a large cohort study

Correction: Inflammatory biomarkers in cerebral venous thrombosis versus ischemic stroke: a network meta-analysis

Prognostic significance of the C-reactive protein–albumin–lymphocyte index and the pan-immune-inflammation value in ischemic and hemorrhagic stroke: a comparative analysis of subtypes

Reduced global BOLD-CSF coupling in chronic kidney disease-related cognitive impairment: a resting-state functional MRI study

Biomarker role in assessing imaging needs for mild cranial trauma (BRAIN-CT): study protocol for a single-center, randomized controlled trial

Association between advanced lung cancer inflammation index levels and ischemic stroke in patients with atrial fibrillation: a propensity score-matching analysis

Development of a clinical prediction model for inflammatory biomarkers and enlarged basal ganglia perivascular spaces using SHAP analysis: feature selection and model interpretation

Admission monocyte-to-albumin ratio predicts 3-month functional outcomes after acute ischemic stroke: a retrospective cohort study

Machine learning–driven risk prediction of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage using peripheral inflammatory markers

Longitudinal association of retinal morphology and white matter progression in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations

HMOX1 mRNA combined with early imaging parameters for predicting the prognosis of hypertensive cerebral hemorrhage patients undergoing conservative treatment

Inflammatory biomarkers in cerebral venous thrombosis versus ischemic stroke: a network meta-analysis

Impact of PCSK9 inhibitor on T lymphocyte subsets and cytokines in patients with acute ischemic stroke: an exploratory analysis of a randomized clinical trial

Correction: Identification of stroke biomarkers using proteomic profiling of extracellular vesicles derived from human blood: a preliminary study

Association between the systemic inflammatory response index and acute ischemic stroke in young people

Receptor-mediated mitophagy: a new target of neurodegenerative diseases

Peripheral blood immune inflammatory markers in neuromyelitis optica spectrum disorders