ORIGINAL RESEARCH article

Front. Nutr.

Sec. Nutritional Epidemiology

Volume 12 - 2025 | doi: 10.3389/fnut.2025.1561909

Associations of body mass index and waist circumference with all cause mortality in the oldest old with cognitive impairment: a prospective cohort study

Provisionally accepted
Xiaopeng  LiXiaopeng Li1Peng  ZhaoPeng Zhao2Mei  ZhaoMei Zhao3*
  • 1First Affiliated Hospital of Henan University, Kaifeng, Henan Province, China
  • 2Lankao Hospital of Traditional Chinese Medicine, Kaifeng, Henan Province, China
  • 3The First Affiliated Hospital of Nanchang University, Nanchang, China

The final, formatted version of the article will be published soon.

In clinical practice, reducing body mass index (BMI), and waist circumference (WC) is a crucial treatment target for minimizing health risks. However, the association patterns between BMI, WC, and all cause mortality in cognitively impaired older adults remain unknown.To investigate the association patterns between body mass index (BMI), waist circumference (WC), and all cause mortality among cognitively impaired oldest old. DESIGN, SETTING, AND PARTICIPANTS The cognitively impaired oldest old from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) in the 2011-2014 wave was included. A restricted cubic spline based on Cox proportional hazards model was used to examine the association patterns. EXPOSURES The global cognitive function of participants was assessed by the Minimum-Mental State Examination. MAIN OUTCOMES AND MEASURES All cause mortality was the outcome. RESULTS A total of 2124 participants (1522 females [71.7%]) were included in this study and 1071

Keywords: Body Mass Index, Waist Circumference, All cause mortality, The oldest old, cognitive impairment

Received: 24 Jan 2025; Accepted: 18 Jun 2025.

Copyright: © 2025 Li, Zhao and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Mei Zhao, The First Affiliated Hospital of Nanchang University, Nanchang, China

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