CLINICAL TRIAL article
Front. Nutr.
Sec. Nutrition and Metabolism
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1576024
Kaempferia Parviflora Extract Reduces Body Fat in Adults Who are Overweight: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial
Provisionally accepted
- 1Dongguk University Gyeongju, Gyeongju, Republic of Korea
- 2Daehan Chemtech Co., Ltd, Seoul, Republic of Korea
- 3Tokiwa Phytochemical Co., Ltd., Sakura, Chiba, Japan
- 4College of Korean Medicine, Semyung University, Jecheon, Republic of Korea
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Background/Objectives: Kaempferia parviflora extract has been reported to alleviate obesity. However, few studies have investigated this topic and none have evaluated its potential among Koreans. Therefore, we aimed to evaluate the efficacy of K. parviflora extract in body fat reduction among Korean adults. Methods: In total, 108 individuals were screened and randomly assigned to the intervention and control groups, and the results of 83 participants were analyzed. Changes from baseline (when the consumption of test and control foods commenced) to the end of the 12 th week, were compared. The primary endpoints were body fat mass and body fat percentage changes, measured using dual-energy X-ray absorptiometry. The secondary endpoints were changes in (1) lean body mass; (2) total fat area, subcutaneous fat area, visceral fat area, and visceral subcutaneous fat ratio; (3) body weight, body mass index, waist circumference, hip circumference, and waist-to-hip circumference ratio; (4) serum total cholesterol, low-density lipoprotein cholesterol, triglyceride, high-density lipoprotein cholesterol, leptin, and adiponectin;(5) and body fat mass, body fat percentage, and lean body mass by region (arms, legs, trunk, android, and gynoid). Results: After 12 weeks, body fat, body weight, and body mass index significantly reduced in the intervention group compared with the control group. Similar findings were observed for total fat area, subcutaneous fat area, visceral fat area, and visceral subcutaneous fat ratio. However, no significant difference was observed in waist and hip circumference values. Additionally, the intervention food was determined to be safe. Conclusions: This study suggests that health functional foods are effective in reducing body fat, thereby preventing various obesityrelated diseases and metabolic syndromes.
Keywords: Kaempferia parviflora, Body Weight, Obesity, Overweight, body fat, fat reduction, randomized controlled trial
Received: 13 Feb 2025; Accepted: 12 May 2025.
Copyright: © 2025 Sung, Kim, Oh, Eun, Tatsuzaki, Shin and Jeong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Seon Mi Shin, College of Korean Medicine, Semyung University, Jecheon, Republic of Korea
Su Hyeon Jeong, College of Korean Medicine, Semyung University, Jecheon, Republic of Korea
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.