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ORIGINAL RESEARCH article

Front. Nutr.

Sec. Nutritional Epidemiology

Volume 12 - 2025 | doi: 10.3389/fnut.2025.1595919

Factors Associated with the Use of Combined Nutritional Complementary and Alternative Medicine (CAM) Among Southern U.S. Older Adults: Results from the Study of Aging II

Provisionally accepted
  • 1University of Alabama at Birmingham, Birmingham, United States
  • 2University of Central Arkansas, Conway, Arkansas, United States
  • 3University of Mississippi Medical Center, Jackson, Mississippi, United States
  • 4Marshall University, Huntington, Indiana, United States
  • 5LSU Health Sciences Center New Orleans, Louisiana State University, New Orleans, Louisiana, United States
  • 6School of Medicine, Washington University in St. Louis, St. Louis, Missouri, United States

The final, formatted version of the article will be published soon.

Background: Older adults use nutritional complementary and alternative medicine (CAM) to reduce the risk of (or treat) non-communicable conditions and diet deficiencies. While prior research has explored the individual use of dietary supplements, vitamins, and minerals among older adults, few studies have examined factors influencing the combined use of these modalities, especially among Southern, older adults in the U.S. Methods: Data were extracted from 419 participants from the University of Alabama at Birmingham Study of Aging II, a population-based longitudinal study of mobility among community-dwelling older adults. Self-reported data, including insurance and rural residence status, was collected. Comorbidity burden was assessed using the Charlson Comorbidity Index. Participants reported their use of non-prescribed medications, including dietary supplements, vitamins, and minerals. Logistic regression was used to identify factors associated with the use of combined nutritional CAM modalities.We found a statistically significant association between sex (p <0.001), age (p= 0.024), rural living status (p= 0.008), and education (p <0.001) in use of combined nutritional CAM (dietary supplements, vitamins, and minerals). For the use of vitamins and minerals only, our findings suggest a significant association between sex (p = 0.027), age (p < 0.001), and education (p=0.009). Lastly, for the use of dietary supplements only, our findings suggest a significant association between age (p =0.050 and education (p=0.002).Our study addresses a critical gap by examining the sociodemographic and chronic disease burden predictors of concurrent use of combined nutritional CAM modalities among older adults in the Southern U.S. Such insights can help inform public health strategies and clinical guidance aimed at supporting the health and well-being of older adults, particularly as they navigate complex health decisions in the context of aging.

Keywords: Nutrition1, Older Adults2, dietary supplements3, vitamins4, complementary and alternative medicine5

Received: 19 Mar 2025; Accepted: 21 Jul 2025.

Copyright: © 2025 Allen-Watts, Rumble, Taylor, Sims, Antoine, Logan, Brown, Buford, Goodin, Cherrington and Kennedy. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Kristen Allen-Watts, University of Alabama at Birmingham, Birmingham, United States

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