REVIEW article
Front. Nutr.
Sec. Nutrition and Food Science Technology
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1596673
This article is part of the Research TopicAdvanced Biosensors and Chemosensors toward Mycotoxins Analysis for Food SafetyView all articles
A comprehensive review on optical and electrochemical aptasensor for detection of Fumonisin B1
Provisionally accepted
- Yangzhou University, Yangzhou, China
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Fumonisin B1 (FB1) contamination has emerged as a global concern due to its high incidence, severe toxicity, and profound implications for food safety and human health. Consequently, there is an urgent demand for the development of novel analytical techniques that enable simple, rapid, and accurate detection of FB1.Conventional methods for mycotoxin analysis, such as high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), thin-layer chromatography (TLC), gas chromatography-mass spectrometry (GC-MS), and enzyme-linked immunosorbent assay (ELISA), often suffer from limitations including high cost, time-consuming procedures, environmental sensitivity, and reliance on specialized expertise. Nucleic acid aptamers, generated via Systematic Evolution of Ligands by Exponential Enrichment (SELEX), have garnered significant attention as next-generation bioreceptors, demonstrating remarkable progress in food safety applications. Leveraging their high specificity and strong affinity for target molecules, aptamers have been successfully employed as alternatives to conventional methods for FB1 detection, leading to the development of diverse aptasensor platforms. This review systematically summarizes recent advancements (2013)(2014)(2015)(2016)(2017)(2018)(2019)(2020)(2021)(2022)(2023)(2024)(2025) in optical and electrochemical aptasensors for FB1 detection, elucidating their working principles, merits, and limitations. It further evaluates the impact of material integration on sensor performance, identifies existing limitations in selected aptasensor configurations, and proposes corresponding optimization strategies. Finally, the current challenges hindering the practical implementation of aptasensors are critically analyzed, and future research directions are outlined to advance this promising field.
Keywords: Fumonisin B1, Aptasensors, Optical signal, Electrochemical signal, Food Safety
Received: 20 Mar 2025; Accepted: 03 Jun 2025.
Copyright: © 2025 Ma and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaodong Guo, Yangzhou University, Yangzhou, China
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