ORIGINAL RESEARCH article

Front. Nutr.

Sec. Nutrition and Metabolism

Volume 12 - 2025 | doi: 10.3389/fnut.2025.1623478

This article is part of the Research TopicNatural Products: A Microecological Perspective for Treating Diabetes and its ComplicationsView all articles

Synergistic Effect of Carbohydrate-Controlled Diet and Cuminum Cyminum Herbal Infusion on Metabolic Syndrome

Provisionally accepted
Maria  AslamMaria Aslam1*Habib-ur-Rehman  .Habib-ur-Rehman .1Tabussam  TufailTabussam Tufail1Yousaf  AlmehmadiYousaf Almehmadi2Wajd Abdullatif  AbualamahWajd Abdullatif Abualamah3Abdullah R.  AlzahraniAbdullah R. Alzahrani4Imran  ShahidImran Shahid4
  • 1University of Lahore, Lahore, Pakistan
  • 2king abdul aziz university, rabigh, Saudi Arabia
  • 3Preventive Medicine Executive Directory Makkah Health Cluster, Makkah, Saudi Arabia
  • 4Umm Al-Qura University, Makkah, Saudi Arabia

The final, formatted version of the article will be published soon.

Background: Metabolic syndrome (MetS) is a growing global health concern and a major risk factor for conditions such as diabetic nephropathy and atherosclerosis. It is marked by chronic inflammation, insulin resistance, and dyslipidemia. Dietary interventions, including carbohydratecontrolled diets, have shown potential in improving metabolic outcomes. Cuminum cyminum (cumin), containing the bioactive compound cumin aldehyde, is known for its hypoglycemic and antioxidant properties. Aim: To evaluate the combined effect of a carbohydrate-controlled diet and cumin herbal infusion on metabolic and biochemical parameters in patients with metabolic syndrome. Methods: A pre-post interventional study was conducted among 132 patients (aged 18-60 years) diagnosed with MetS based on ATP III criteria. Participants were recruited from the University of Lahore Teaching Hospital through purposive sampling and randomly assigned to control or intervention groups (n = 66 each). The intervention group received a carbohydratecontrolled diet and cumin infusion for eight weeks. Anthropometric, biochemical, and physiological parameters were assessed at baseline and post-intervention. Two-way repeated measures ANOVA was used for statistical analysis. Results: Significant improvements were observed in BMI, body weight, and lipid profile parameters (p < 0.005). The intervention group showed notable reductions in triglycerides, LDL, and fasting blood glucose levels compared to the control group. Conclusion: A carbohydrate-controlled diet combined with cumin infusion may support glycemic control and improve lipid metabolism in individuals with metabolic syndrome.This combined approach shows potential as an adjunct dietary strategy for managing cardiometabolic risk factors.

Keywords: Carbohydrate diet, Cumin cyminum, metabolic syndrome, BMI, Cumin aldehyde, Glucose

Received: 06 May 2025; Accepted: 24 Jun 2025.

Copyright: © 2025 Aslam, ., Tufail, Almehmadi, Abualamah, Alzahrani and Shahid. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Maria Aslam, University of Lahore, Lahore, Pakistan

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