ORIGINAL RESEARCH article
Front. Nutr.
Sec. Nutrition and Food Science Technology
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1625260
Characterization of the polysaccharide from Bletilla striata and its inhibitory actions on amylolytic enzymes and prebiotic activity
Provisionally accepted
- Harbin Normal University, Harbin, China
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In the current study, a new polysaccharide (BSP) with the average molecular weight (Mw) of 85.4 kDa was gained from Bletilla striata. The inhibition effects of BSP on α-amylase and α-glucosidase and the prebiotic properties were determined.The results showed that BSP was a neutral polysaccharide and composed of mannose, glucose, and galactose with a relative molar ratio of 3.2:5.4:1.0. The main sugar residues in BSP were →4)-α-D-Glcp-(1→, →6)-β-D-Galp-(1→, →4)-β-D-Manp-(1→ and β-D-Manp-(1→. BSP displayed strong inhibitory effects against α-amylase and α-glucosidase, and exhibited competitive inhibitory kinetics.At 4.0 mg/mL, the inhibitory rates of 67.75 ± 0.45% on α-amylase and 48.24 ± 1.02% on α-glucosidase were obtained, respectively. Moreover, BSP can be used as carbon source to facilitate the proliferation of probiotics. These findings support the potential application of BSP for the diabetes.
Keywords: Bletilla striata polysaccharide, characterization, Hypoglycemic function, Prebiotics, diabetes
Received: 08 May 2025; Accepted: 07 Jul 2025.
Copyright: © 2025 Fu, Deng and Gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jun Gao, Harbin Normal University, Harbin, China
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