REVIEW article
Front. Nutr.
Sec. Clinical Nutrition
Intervention strategies for Cancer-Related Sarcopenia:a scoping review
Provisionally accepted
- 1Shaoxing People‘s Hospital, Zhejiang, China
- 2Shaoxing University, Shaoxing, China
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Objective: This article systematically reviewed intervention strategies for Cancer-Related Sarcopenia (CRS), providing evidence for researchers to develop targeted treatments. Methods: Four databases (PubMed, Embase, Web of Science, Cochrane Library) were searched for studies (2015–2025), followed by literature screening and content analysis. Results: A total of 3,566 articles were initially retrieved; 18 randomized controlled trials (2016-2025, sample size 15-232) were finally included. CRS interventions fell into four categories: nutritional, exercise, pharmacological, and multidisciplinary. Conclusions: CRS intervention needs an integrated approach of nutrition, exercise, pharmacology, and multidisciplinary team (MDT) to improve patients' function and quality of life. Future research should focus on precision and translational medicine.
Keywords: Cancer, Sarcopenia, intervention strategies, Rehabilitation, RCT - randomized controlled trial
Received: 02 Sep 2025; Accepted: 21 Nov 2025.
Copyright: © 2025 Li, Zhu, Chen, Shan and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jiamin Xu, xjm996996@163.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.