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REVIEW article

Front. Nutr.

Sec. Nutrition and Food Science Technology

Volume 12 - 2025 | doi: 10.3389/fnut.2025.1689700

This article is part of the Research TopicHealth Effects of Natural Compounds from PlantsView all 16 articles

The Green Healer; An Updated Review on the Phytochemical Profile and Therapeutic Potential of Aloe vera

Provisionally accepted
Aimen  AbidAimen Abid1Mavra  JavedMavra Javed2Saira  ZafarSaira Zafar3Syeda Andleeb Zahra  HamdaniSyeda Andleeb Zahra Hamdani1Syed Hassan Bin Usman  ShahSyed Hassan Bin Usman Shah4Juweria  AbidJuweria Abid1Abdul Momin Rizwan  AhmadAbdul Momin Rizwan Ahmad5*
  • 1National University of Medical Sciences, Rawalpindi, Pakistan
  • 2Michigan State University, East Lansing, United States
  • 3Health Services Academy, Islamabad, Pakistan
  • 4University of New South Wales, Sydney, Australia
  • 5University of York, York, United Kingdom

The final, formatted version of the article will be published soon.

Aloe vera has historically been recognized as a versatile medicinal plant, attributable to its extensive array of therapeutic properties. Recent scientific research has shown a diverse array of bioactive compounds in Aloe vera that contribute to its potential pharmacological capabilities. This review synthesizes contemporary data on the phytochemistry, health benefits, and potential clinical applications of Aloe vera. Anthraquinones, flavonoids, polysaccharides, and other bioactive substances found in Aloe vera exhibit significant anti-inflammatory, antioxidant, antibacterial, and immunomodulatory effects. Furthermore, its nutritional composition is exceptionally varied, since Aloe vera contains prominent vitamins, minerals, and amino acids, rendering it an outstanding supplement for sustaining overall health. Its applications have been validated in the therapy of metabolic disorders, gastrointestinal recovery, improvement of dermatological conditions, and wound healing. Aloe vera continues to garner interest in both conventional and contemporary healthcare systems due to its affordability, accessibility, and safety profile as an integrative approach.

Keywords: aloe vera, anti-inflammatory effects, Antimicrobial activity, Antioxidantproperties, bioactive compounds, Therapeutic potential

Received: 20 Aug 2025; Accepted: 12 Sep 2025.

Copyright: © 2025 Abid, Javed, Zafar, Hamdani, Shah, Abid and Ahmad. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Abdul Momin Rizwan Ahmad, abdul.momin@york.ac.uk

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.