Frontiers in Oncology

Case Report

Published on 12 Dec 2025

Remarkable response to pembrolizumab in PD-L1 overexpressing (≥ 50%) NSCLC and extracranial abscopal effect induced by brain radiotherapy: a case report

in Thoracic Oncology

Yong Xia
Hongfan Zhu
Shaoqing Huang
Xinhong Guan
Xiuxiu Chen
Qian Zhang
Liu Meng
Hui Xue
Haiyan Xiang
Shenglan Lai

Frontiers in Oncology

doi 10.3389/fonc.2025.1652515

335 views

Study Protocol

Published on 12 Dec 2025

Home-Combo: an online home-based exercise intervention for women with breast cancer undergoing neoadjuvant chemotherapy: study protocol for a 2-arm pragmatic randomized controlled trial

in Breast Cancer

Pedro G.F. Ramos
Eliana V. Carraça
Gabriela Valadas
Rui M. Batalau
António L. Palmeira
Marlene N. Silva
Patrícia C. Viegas
Jorge G. Oliveira
Sara S. Pereira
António Videira-Silva

Frontiers in Oncology

doi 10.3389/fonc.2025.1682839

626 views

Original Research

Published on 12 Dec 2025

Cetrorelix promotes cell apoptosis via the PI3K–AKT–FOXO1 pathway in epithelial ovarian cancer

in Molecular and Cellular Oncology

Ning Zhang
Yu Liu
Xiaodan Zhang
Meng Xie
Ying Zhang
Keqin Hua

Frontiers in Oncology

doi 10.3389/fonc.2025.1631576

399 views

Original Research

Published on 12 Dec 2025

Characterization of ocular adverse events associated with crizotinib: real-world insights from the two global pharmacovigilance databases of FAERS and VigiBase

in Cancer Molecular Targets and Therapeutics

Shuai Dong
Zhi-chao Jiang
Li Gao
Rong Zhang
Yan Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1735200

420 views

Systematic Review

Published on 12 Dec 2025

Comparative efficacy of various physical therapies on pain, fatigue, quality of life and functional impairment in breast cancer survivors: a network meta-analysis of randomized controlled trials

in Breast Cancer

Yuan Luo
Qi Huang
Xiao Chen
Hongju Peng
Yu Li
Li Chen
Liyue Zhang
Yi Huang

Frontiers in Oncology

doi 10.3389/fonc.2025.1699682

359 views

Systematic Review

Published on 12 Dec 2025

Non-systemic treatment of metastatic kidney cancer: systematic review and a case report

in Genitourinary Oncology

Gabija O. Morkunaite
Ugne Mickeviciute
Mantas Trakymas
Marius Kincius
Vincas Urbonas
Giedrius Kvederas
Ausvydas Patasius

Frontiers in Oncology

doi 10.3389/fonc.2025.1627467

502 views

Original Research

Accepted on 11 Dec 2025

Prognostic value of tumour-associated neutrophils in different polarization status releasing neutrophil extracellular traps in the immunotherapy of advanced non-small cell lung cancer

in Cancer Immunity and Immunotherapy

Weiwei Hong
Xin Ye
Lin Chen
Xiangzhi Chai
Yan Yin
Zhaoqing Li
Chen Fang
Xiaoying Qian
Biao Yu
Guizhen Qin

Frontiers in Oncology

Review

Accepted on 11 Dec 2025

Frontiers of Cytokine Engineering in CAR Cell Therapy for Cancer

in Cancer Immunity and Immunotherapy

Yan-Ruide Li
Yinghan Wu

Frontiers in Oncology

103 views

Original Research

Accepted on 11 Dec 2025

A Comparative Dosimetric Study of Hypofractionated Radiotherapy with Different Target Volume Delineation Approaches in Breast Cancer Patients After Implant-Based Reconstruction

in Breast Cancer

Lipeng Ding
Xu Wang
Zhangcai Zheng
Jianping Long
Guoying Miu
Tao Yang
Shuxia Li
Na Dong
Liying Gao

Frontiers in Oncology

Brief Research Report

Accepted on 11 Dec 2025

Prognostic and Predictive Impact of NOTCH1 Mutations in Patients with Chronic Lymphocytic Leukemia: A Tertiary Single-Center Experience

in Hematologic Malignancies

Mattia D'Antiga
Andrea Serafin
Francesco Angotzi
Alessandro Cellini
Arianna Bevilacqua
Giovanni Leone
Nicolò Danesin
Chiara Adele Cavarretta
Francesco Piazza
Erich Piovan

Frontiers in Oncology

Original Research

Accepted on 11 Dec 2025

Multimodal Ultrasonography for Predicting Epidermal Growth Factor Receptor Mutation in Subpleural Non-small Cell Lung Carcinoma

in Cancer Imaging and Image-directed Interventions

Jing Bai
Fei Qi Zhang
Song Wang
Hong Wang
KUN YAN
Wei Zhou
Wei Yang
Liang Dong

Frontiers in Oncology

Case Report

Accepted on 11 Dec 2025

Primary Epithelioid Angiosarcoma of the Jejunum Presenting with Severe Anemia and Distant Metastasis: A Case Report and Literature Review

in Gastrointestinal Cancers: Colorectal Cancer

Liu Shurong
zhang junling
Xin Wang

Frontiers in Oncology

Original Research

Accepted on 11 Dec 2025

Pan-Immune-Inflammation Value as an Independent Prognostic Marker in Patients with Brain Metastases

in Neuro-Oncology and Neurosurgical Oncology

Jiacheng Li
Menghan Liu
Yingtong Liu
Zheran Liu
Jiazhen Liu
Yuping Xie

Frontiers in Oncology

102 views

Case Report

Accepted on 11 Dec 2025

Multidisciplinary Management of Surgery and Postoperative Recurrence in Stage IV Gallbladder Cancer Following Conversion Therapy: A Case Report

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Junfeng Cheng
Xuemin Li
Chao Ren
Shian Yu
Hongwei Huang
Zhou Shishi
Jianji Dai

Frontiers in Oncology

Original Research

Accepted on 11 Dec 2025

Unveiling the Prognostic Role of FABP4 in Early-Onset Colorectal Cancer through Big Data Analysis and Preliminary Clinical Validation

in Gastrointestinal Cancers: Colorectal Cancer

Yu Wu
Weiwei Zou
Shengjun Zhang
Lipeng Zhao
Shaohua He
Fan Yao
Peilin Qing
Yixin Li
Jie Li
Xiao-Liang Xing

Frontiers in Oncology

141 views

Review

Accepted on 11 Dec 2025

Roles of E3 Ubiquitin Ligases and Deubiquitinating Enzymes in Renal Cell Carcinoma

in Molecular and Cellular Oncology

Minshu Jiang
Yi Quan
Wenxia Si
Minghui Zhang
Sien Huan
Sha Qu

Frontiers in Oncology

101 views

Original Research

Accepted on 11 Dec 2025

Identification of ZFP161 as a regulator of the c-Myc oncogene in human colon tissue

in Molecular and Cellular Oncology

Grania Christyani
Fei Zhao
Yening Feng
Hyorin Lee
XINYI TU
Chao Zhang
Zhenkun Lou
Wootae Kim

Frontiers in Oncology

145 views

Case Report

Accepted on 11 Dec 2025

Case Report: Giant Uterine Broad Ligament Fibroid

in Gynecological Oncology

Weiwei QIAN
Shaoqin Sheng
Xiangqian Xv
Jiaxin Miao
Yanying Nong

Frontiers in Oncology

202 views

Brief Research Report

Accepted on 11 Dec 2025

Efficacy and Tolerability of Mogamulizumab in Mycosis Fungoides and Sézary Syndrome: A Monocentric Retrospective Study

in Hematologic Malignancies

Antonio Giordano
Luana Fianchi
Marianna Criscuolo
Martina Quattrone
Alessia Di Pilla
Livio Pagano

Frontiers in Oncology

Review

Accepted on 11 Dec 2025

Ultrasound-based Radiomics for the Evaluation of Breast Cancer

in Cancer Imaging and Image-directed Interventions

Fei-Yi Sun
De-Li Meng
Lin Liu
Xiu-Qun Cao
Lu Fu
Lei Meng
Xin-Wu Cui
Xiao-Fang Pan

Frontiers in Oncology

100 views

Review

Accepted on 11 Dec 2025

Recent advance in early oral lesion diagnosis: The application of artificial intelligence-assisted endoscopy

in Cancer Imaging and Image-directed Interventions

XINYI ZHAO
Hao Lin
BANG ZENG
RENBIN ZhOU
LEI MA
Bing Liu
QIUSHENG SHAN
Tianfu Wu

Frontiers in Oncology

Original Research

Accepted on 11 Dec 2025

Oophorectomy followed by postoperative chemotherapy for ovarian metastasis of colorectal cancer: a retrospective analysis

in Gastrointestinal Cancers: Colorectal Cancer

YuHua Zhang
Guangyue Zhao
Yun Qiao
Yongchao Ba
Ye Tian
Xing Song
Ning Guan
Xiaoqian Hou
Yan Zhang

Frontiers in Oncology

167 views

Original Research

Accepted on 11 Dec 2025

Utility of extended HPV genotyping in cervical cancer screening: a prospective population-based cohort study in China

in Cancer Epidemiology and Prevention

Kexin Yi
Jinyu Zhang
Hong Wang
Peipei Chen
Xingyuan Sun
Mengjie Li

Frontiers in Oncology

Review

Published on 11 Dec 2025

Lactylation in digestive system tumors: from mechanisms to therapeutic target

in Cancer Molecular Targets and Therapeutics

Jun Wei
Qian Ding
Hongjun Wang
Yang Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1607249

586 views

34,155 articles

articles

Remarkable response to pembrolizumab in PD-L1 overexpressing (≥ 50%) NSCLC and extracranial abscopal effect induced by brain radiotherapy: a case report

Home-Combo: an online home-based exercise intervention for women with breast cancer undergoing neoadjuvant chemotherapy: study protocol for a 2-arm pragmatic randomized controlled trial

Cetrorelix promotes cell apoptosis via the PI3K–AKT–FOXO1 pathway in epithelial ovarian cancer

Characterization of ocular adverse events associated with crizotinib: real-world insights from the two global pharmacovigilance databases of FAERS and VigiBase

Comparative efficacy of various physical therapies on pain, fatigue, quality of life and functional impairment in breast cancer survivors: a network meta-analysis of randomized controlled trials

Non-systemic treatment of metastatic kidney cancer: systematic review and a case report

Prognostic value of tumour-associated neutrophils in different polarization status releasing neutrophil extracellular traps in the immunotherapy of advanced non-small cell lung cancer

Frontiers of Cytokine Engineering in CAR Cell Therapy for Cancer

A Comparative Dosimetric Study of Hypofractionated Radiotherapy with Different Target Volume Delineation Approaches in Breast Cancer Patients After Implant-Based Reconstruction

Prognostic and Predictive Impact of NOTCH1 Mutations in Patients with Chronic Lymphocytic Leukemia: A Tertiary Single-Center Experience

Multimodal Ultrasonography for Predicting Epidermal Growth Factor Receptor Mutation in Subpleural Non-small Cell Lung Carcinoma

Primary Epithelioid Angiosarcoma of the Jejunum Presenting with Severe Anemia and Distant Metastasis: A Case Report and Literature Review

Pan-Immune-Inflammation Value as an Independent Prognostic Marker in Patients with Brain Metastases

Multidisciplinary Management of Surgery and Postoperative Recurrence in Stage IV Gallbladder Cancer Following Conversion Therapy: A Case Report

Unveiling the Prognostic Role of FABP4 in Early-Onset Colorectal Cancer through Big Data Analysis and Preliminary Clinical Validation

Roles of E3 Ubiquitin Ligases and Deubiquitinating Enzymes in Renal Cell Carcinoma

Identification of ZFP161 as a regulator of the c-Myc oncogene in human colon tissue

Case Report: Giant Uterine Broad Ligament Fibroid

Efficacy and Tolerability of Mogamulizumab in Mycosis Fungoides and Sézary Syndrome: A Monocentric Retrospective Study

Ultrasound-based Radiomics for the Evaluation of Breast Cancer

Recent advance in early oral lesion diagnosis: The application of artificial intelligence-assisted endoscopy

Oophorectomy followed by postoperative chemotherapy for ovarian metastasis of colorectal cancer: a retrospective analysis

Utility of extended HPV genotyping in cervical cancer screening: a prospective population-based cohort study in China

Lactylation in digestive system tumors: from mechanisms to therapeutic target