Frontiers in Oncology | Hematologic Malignancies

Case Report

Published on 13 Jan 2026

Case Report: Pediatric AML with TBC1D15::RAB21 fusion and FLT3-ITD/NPM1 co-mutation: diagnostic pitfalls in morphologic mimicry of acute promyelocytic leukemia

in Hematologic Malignancies

Qiang Yao
Xiaoyong Chen
Meizhu Luo
Zhenhu Lin
Xiaoying Fu

Frontiers in Oncology

doi 10.3389/fonc.2025.1683005

776 views

Brief Research Report

Published on 13 Jan 2026

Prognostic and predictive impact of NOTCH1 mutations in patients with chronic lymphocytic leukemia: a tertiary single-center experience

in Hematologic Malignancies

Mattia D’Antiga
Andrea Serafin
Francesco Angotzi
Alessandro Cellini
Arianna Bevilacqua
Giovanni Leone
Nicolò Danesin
Chiara Adele Cavarretta
Francesco Piazza
Erich Piovan

Frontiers in Oncology

doi 10.3389/fonc.2025.1726439

742 views

Case Report

Published on 12 Jan 2026

Sintilimab combined with AVD for the treatment of composite Hodgkin lymphoma and follicular lymphoma: a case report and literature review

in Hematologic Malignancies

Huami Ye
Linlin Huang
Changqian Chen
Shihua Huang
Lianjie Hu
Ling Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1692954

517 views

Case Report

Published on 12 Jan 2026

Headache as the initial symptom in two cases of multiple myeloma: a case report and literature review

in Hematologic Malignancies

Denglu Liu
Minghui Du
Xiaoyu Gao

Frontiers in Oncology

doi 10.3389/fonc.2025.1718989

1,428 views

Original Research

Accepted on 09 Jan 2026

A real-world 10-year follow-up analysis of survival and safety of CD20-targeted therapy in patients with Waldenstrom macroglobulinemia

in Hematologic Malignancies

Xufei Huang
Zhihong Zheng
Zhihong Zheng
Rong Zhan
Shaoyuan Wang

Frontiers in Oncology

148 views

Case Report

Published on 09 Jan 2026

Case Report: Successful treatment of pulmonary lymphomatoid granulomatosis with a PD-1 inhibitor-based regimen

in Hematologic Malignancies

Xiaoyan Liu
Qi Gao
Feifei Wu
Junli Jia
Li Cao
Qingfeng Yu
Dandan Zhang
Wugan Zhao
Jie Ma

Frontiers in Oncology

doi 10.3389/fonc.2025.1700813

700 views

Original Research

Published on 09 Jan 2026

Survival improvement in primary plasma cell leukemia: a retrospective analysis of novel agent-based regimens and stem cell transplantation

in Hematologic Malignancies

Yong Xu
Jie He
Lanxin Chen
Jinwen Liu
Min Zhou
Bing Chen
Hua Bai

Frontiers in Oncology

doi 10.3389/fonc.2025.1727117

740 views

Original Research

Published on 09 Jan 2026

Multi-isocentric volumetric arc-based total body irradiation: radiation dose impact on oncological outcomes in patients receiving allogeneic hematopoietic cell transplantation

in Hematologic Malignancies

Anna Romanowska
Joanna Kamińska
Alicja Sadowska-Klasa
Anita Prawdzik–Dampc
Renata Zaucha

Frontiers in Oncology

doi 10.3389/fonc.2025.1695178

572 views

Original Research

Published on 08 Jan 2026

Prognostic factors associated with recurrent COVID-19 and impact of SARS-CoV-2 vaccine on patients with chronic lymphocytic leukemia

in Hematologic Malignancies

Sara Pepe
Roberta Mazzarella
Costanza Andriola
Tania Soriano
Giorgio Sforzini
Francesca Romana Mauro

Frontiers in Oncology

doi 10.3389/fonc.2025.1737446

857 views

Review

Published on 06 Jan 2026

Ocular toxicities of targeted therapies and immunotherapies in hematologic malignancies

in Hematologic Malignancies

Mohammad S. Aqil
Yzen Al-Marrawi
Marcus Yaldo
Ahmad Abu-Mahfouz
Lavi Singh
Swathi Gopishetty
Precious Idogun
Daniel Ezekwudo
Ishmael Jaiyesimi
Adam J. Weiner

Frontiers in Oncology

doi 10.3389/fonc.2025.1691518

1,333 views

Systematic Review

Published on 06 Jan 2026

Clinical efficacy and safety of umbralisib, a dual PI3Kδ/CK1-ϵ inhibitor, in treatment of hematologic malignancies

in Hematologic Malignancies

Yunke Zang
Hai-en Cheng
Yanhua Sun
Jingfei Wang
Yuying Zhao
Jingning Yang
Yongping Liu
Yanli Sun

Frontiers in Oncology

doi 10.3389/fonc.2025.1591759

720 views

Systematic Review

Published on 06 Jan 2026

Efficacy, safety and economy of denosumab and zoledronic acid in the treatment of bone metastases of solid tumors and multiple myeloma: a systematic review and meta-analysis

in Hematologic Malignancies

Li Zhong
Wei Chen
Da Zheng
Yuening Cao
Ling Zhu
Zefeng Zhu
Luqin Liao
Lilin Dai
Xiaotao Wang
Zheng Zeng

Frontiers in Oncology

doi 10.3389/fonc.2025.1747354

1,110 views

Systematic Review

Published on 06 Jan 2026

Infection risks associated with daratumumab-containing regimens in multiple myeloma: a systematic review and meta-analysis

in Hematologic Malignancies

Zeng-Yi Huang
Xiao-Lian Liu
Ting Li
Chao-Han Luo

Frontiers in Oncology

doi 10.3389/fonc.2025.1729177

1,397 views

Case Report

Published on 05 Jan 2026

Case Report: autologous stem cell boost enables hematopoietic recovery after severe cytopenia induced by BCMA-targeted bispecific antibody therapy in multiple myeloma

in Hematologic Malignancies

Hiroaki Akiyama
Seiji Kakiuchi
Akimasa Sakamoto
Naru Tomigaki
Shutaro Fujioka
Isamu Harima
Ryotaro Niwa
Ikumi Takagi
Yoko Kozuki
Yoshiharu Miyata

Frontiers in Oncology

doi 10.3389/fonc.2025.1705843

1,165 views

Original Research

Published on 05 Jan 2026

Dominant TET2 mutations predict adverse prognosis in cytogenetically normal acute myeloid leukemia patients

in Hematologic Malignancies

Zhuanghui Hao
Jingjing Xia
Sicheng Bian
Miaoke Song
Miao Zhang
Jingyi Feng
Shuo Li
Huichao Wang
Yaofang Zhang
Wanfang Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1730830

1,039 views

Case Report

Published on 05 Jan 2026

Myeloid sarcoma masquerading as central nervous system diffuse large b-cell lymphoma: a case report and literature review

in Hematologic Malignancies

Wanli Hu
Yang Liu
Chengcheng Ma
Yuexian Gao
Pengyun Zeng
Huiling Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1712803

716 views

Case Report

Published on 05 Jan 2026

Case Report: A case of cervical burkitt lymphoma and literature review

in Hematologic Malignancies

Sen Miao
Yue Bai
Hua Hao

Frontiers in Oncology

doi 10.3389/fonc.2025.1696219

519 views

Original Research

Published on 02 Jan 2026

Construction and validation of a simple, scoreable model for predicting infection risk in patients with multiple myeloma: a retrospective single-center study

in Hematologic Malignancies

Sheng-ke Tu
Jing Yang
Sha-dong Min
Hong-jie Fan
Mimi Hu
Juan Tian
Min Li
Kui Song

Frontiers in Oncology

doi 10.3389/fonc.2025.1672927

627 views

Review

Accepted on 29 Dec 2025

Immune Dysregulation in Hairy Cell Leukemia: A Predisposing Factor for Opportunistic Legionella pneumophila Infections

in Hematologic Malignancies

Shengyi Yu
Xuan An
Lanying Zhang
Yanhui Gu
Yangyao Ou

Frontiers in Oncology

194 views

Original Research

Accepted on 29 Dec 2025

Nomogram to predict hemorrhage risk related to anti-tumor therapy in patients with acute leukemia

in Hematologic Malignancies

Xinxin Hu
Ying He
Yinghua Xie
Li Zhao
Ruijuan Wang
Lijuan Duan
Peipei Mao
Xiyao Han
Yihan Liu
Chao Li

Frontiers in Oncology

108 views

Original Research

Accepted on 22 Dec 2025

A mammalian, glutaminase-free asparaginase enhances venetoclax activity in preclinical AML models with chromosome 7 deletion

in Hematologic Malignancies

Hussein A Abbas
Dhabya Majid
ZHE WANG
Amanda M Schalk
BIn Yuan
Qi Tatarata
Jessica L Root
Araceli Isabella Garza
Mhd Yousuf Yassouf
Basant T Gamal

Frontiers in Oncology

268 views

Mini Review

Accepted on 19 Dec 2025

MRD in Multiple Mieloma: the Clinical Perspective

in Hematologic Malignancies

TOMMASO CARAVITA DI TORITTO
angela rago

Frontiers in Oncology

967 views

Original Research

Published on 19 Dec 2025

Prognostic factors of patients with intravascular large B cell lymphoma: a multicenter study in China

in Hematologic Malignancies

Yan Guo
Yi Zhong
Lixia Zhu
Fengping Zhou
Xuanru Lin
Xian Li
Xiufeng Wang
Yan Huang
Sun Wu
Guoqing Lv

Frontiers in Oncology

doi 10.3389/fonc.2025.1689028

1,106 views

Case Report

Accepted on 18 Dec 2025

Case Report of Two Patients with Refractory HIV-Related 1 B-Cell Lymphoma Treated with the Monoclonal Antibody 2 Glofitamab for Secondary Central Nervous System 3 Involvement

in Hematologic Malignancies

Yueru Ji
Jing Gao
Tong Wei
Miaowang Hao
Weiwei Qin

Frontiers in Oncology

205 views

2,053 articles

articles

Case Report: Pediatric AML with TBC1D15::RAB21 fusion and FLT3-ITD/NPM1 co-mutation: diagnostic pitfalls in morphologic mimicry of acute promyelocytic leukemia

Prognostic and predictive impact of NOTCH1 mutations in patients with chronic lymphocytic leukemia: a tertiary single-center experience

Sintilimab combined with AVD for the treatment of composite Hodgkin lymphoma and follicular lymphoma: a case report and literature review

Headache as the initial symptom in two cases of multiple myeloma: a case report and literature review

A real-world 10-year follow-up analysis of survival and safety of CD20-targeted therapy in patients with Waldenstrom macroglobulinemia

Case Report: Successful treatment of pulmonary lymphomatoid granulomatosis with a PD-1 inhibitor-based regimen

Survival improvement in primary plasma cell leukemia: a retrospective analysis of novel agent-based regimens and stem cell transplantation

Multi-isocentric volumetric arc-based total body irradiation: radiation dose impact on oncological outcomes in patients receiving allogeneic hematopoietic cell transplantation

Prognostic factors associated with recurrent COVID-19 and impact of SARS-CoV-2 vaccine on patients with chronic lymphocytic leukemia

Ocular toxicities of targeted therapies and immunotherapies in hematologic malignancies

Clinical efficacy and safety of umbralisib, a dual PI3Kδ/CK1-ϵ inhibitor, in treatment of hematologic malignancies

Efficacy, safety and economy of denosumab and zoledronic acid in the treatment of bone metastases of solid tumors and multiple myeloma: a systematic review and meta-analysis

Infection risks associated with daratumumab-containing regimens in multiple myeloma: a systematic review and meta-analysis

Case Report: autologous stem cell boost enables hematopoietic recovery after severe cytopenia induced by BCMA-targeted bispecific antibody therapy in multiple myeloma

Dominant TET2 mutations predict adverse prognosis in cytogenetically normal acute myeloid leukemia patients

Myeloid sarcoma masquerading as central nervous system diffuse large b-cell lymphoma: a case report and literature review

Case Report: A case of cervical burkitt lymphoma and literature review

Construction and validation of a simple, scoreable model for predicting infection risk in patients with multiple myeloma: a retrospective single-center study

Immune Dysregulation in Hairy Cell Leukemia: A Predisposing Factor for Opportunistic Legionella pneumophila Infections

Nomogram to predict hemorrhage risk related to anti-tumor therapy in patients with acute leukemia

A mammalian, glutaminase-free asparaginase enhances venetoclax activity in preclinical AML models with chromosome 7 deletion

MRD in Multiple Mieloma: the Clinical Perspective

Prognostic factors of patients with intravascular large B cell lymphoma: a multicenter study in China

Case Report of Two Patients with Refractory HIV-Related 1 B-Cell Lymphoma Treated with the Monoclonal Antibody 2 Glofitamab for Secondary Central Nervous System 3 Involvement