Frontiers in Pediatrics | Pediatric Hematology and Hematological Malignancies

Case Report

Accepted on 23 Sep 2025

Refractory systemic mastocytosis with AML1::ETO+ acute myeloid leukemia driven by rare KIT mutation: remarkable therapeutic efficacy of avapritinib

in Pediatric Hematology and Hematological Malignancies

Song Xue
Man Chen
Hui-Peng Sun
Xingyu Cao

Frontiers in Pediatrics

doi 10.3389/fped.2025.1646001

411 views

Original Research

Accepted on 23 Sep 2025

Study on the Influencing Factors of the First-Line Treatment Response to Primary Immune Thrombocytopenia in Children

in Pediatric Hematology and Hematological Malignancies

Bihan Zhang
Qian Hu
Qiaodao Wu
Jianying Ning

Frontiers in Pediatrics

doi 10.3389/fped.2025.1679463

299 views

Mini Review

Published on 12 Sep 2025

Revisiting cytomegalovirus in pediatric allogeneic hematopoietic stem cell transplant recipients: current strategies for prevention and management in the letermovir era

in Pediatric Hematology and Hematological Malignancies

Lisa Hiskey
Diego R. Hijano
Ramia Zakhour

Frontiers in Pediatrics

doi 10.3389/fped.2025.1663600

1,600 views

Case Report

Published on 04 Sep 2025

Case report: Successful treatment of a patient presenting with a very rare association of acute lymphoblastic leukemia and mucopolysaccharidosis type IVA

in Pediatric Hematology and Hematological Malignancies

Sofia Maria Carlotta Arnaboldi
Martha Caterina Faraguna
Antonella Colombini
Alessandra Sala
Veronica Leoni
Marco Spinelli
Giacomo Gotti
Laura Rachele Bettini
Viola Crescitelli
Anna Commone

Frontiers in Pediatrics

doi 10.3389/fped.2025.1644720

1,441 views

Case Report

Published on 02 Sep 2025

Vitamin B12 deficiency in a young male with Imerslund-Gräsbeck syndrome: case report

in Pediatric Hematology and Hematological Malignancies

Lina Xing
Yujie Guo
Yang Li
Xuquan Zhou
Fengru Lin
Yan Wang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1645600

1,180 views

Editorial

Published on 22 Aug 2025

Editorial: Anemia in children: from nutritional deficits to genetic disorders

in Pediatric Hematology and Hematological Malignancies

Sachith Mettananda
Duantida Songdej
Nirmani Yasara

Frontiers in Pediatrics

doi 10.3389/fped.2025.1678056

1,409 views

Original Research

Published on 20 Aug 2025

Genotype clinical phenotype analysis of 35 cases of hereditary spherocytosis in children

in Pediatric Hematology and Hematological Malignancies

Huang Duowen
Guo Xia
Gao Ju

Frontiers in Pediatrics

doi 10.3389/fped.2025.1650295

819 views

Brief Research Report

Published on 11 Aug 2025

The expression pattern and role of circulating CXCR5+γδ T cells in children with newly diagnosed immune thrombocytopenia

in Pediatric Hematology and Hematological Malignancies

Jian-Yong Wang
Yi Xin
Xiao-Li Wang
Lin-Lin Li
Ai-Min Li
Xiao-Lu Zhang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1646877

1,081 views

Case Report

Published on 11 Aug 2025

Case Report: Eltrombopag in mosaic and gene therapy-treated patients with Fanconi anemia

in Pediatric Hematology and Hematological Malignancies

Josune Zubicaray
June Iriondo
Elena Sebastián
Alejandro Sanz
Paula Rio
Jean Soulier
Sonsoles San Román
José J. Uriz
Susana Navarro
Eileen Nicoletti

Frontiers in Pediatrics

doi 10.3389/fped.2025.1625751

1,229 views

Original Research

Published on 29 Jul 2025

Study on the diagnostic and differential value of thalassemia through combined blood routine examination and reticulocyte detection

in Pediatric Hematology and Hematological Malignancies

Haiyan Ke
Hongxia Zhang
Hong Jiang
Sheng Li
Hui Wang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1616766

1,850 views

Original Research

Published on 24 Jul 2025

Prognostic value of blood inflammatory composite markers in the survival of pediatric patients with secondary hemophagocytic lymphohistiocytosis

in Pediatric Hematology and Hematological Malignancies

Nandu Luo
Xin Xie
Yan Chen
Zuochen Du
Pei Huang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1458490

891 views

Case Report

Published on 18 Jul 2025

Progressive cephalohematoma in a neonate revealing severe hemophilia a owing to intron 22 inversion: a case report

in Pediatric Hematology and Hematological Malignancies

Cheng Peng
Qiuyue Kou
Qianqian Xia
Zhongfen Cao
Lili Liu
Xinlin Hou
Zezhong Tang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1649183

1,552 views

Original Research

Published on 17 Jul 2025

Analysis of risk factors for Epstein–Barr virus reactivation and progression to post-transplant lymphoproliferative disorder in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation

in Pediatric Hematology and Hematological Malignancies

Lanzhou Jia
Hui Yang
Ya Zhou
Yan Meng
Luying Zhang
Xiaoying Lei
Xianming Guan
Jie Yu
Ying Dou

Frontiers in Pediatrics

doi 10.3389/fped.2025.1627990

1,783 views

Original Research

Published on 10 Jul 2025

The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia

in Pediatric Hematology and Hematological Malignancies

Yaojin Sun
Qian Zhang
Xiaojie Gu
Yongjun Fang
Jie Huang
Heng Zhang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1578617

1,502 views

Correction

Published on 02 Jul 2025

Correction: Third generation sequencing transforms the way of the screening and diagnosis of thalassemia: a mini-review

in Pediatric Hematology and Hematological Malignancies

Lixia Zhan
Chunrong Gui
Wei Wei
Juliang Liu
Baoheng Gui

Frontiers in Pediatrics

doi 10.3389/fped.2025.1637415

689 views

Original Research

Published on 05 Jun 2025

Differentiating primary bone marrow failure syndromes in children: a retrospective analysis of early clinical and laboratory features

in Pediatric Hematology and Hematological Malignancies

Yan-Li Leng
Yu-Qi Zhao
Hong-Juan Li
Yan Gu
Yan Han
GuYu Ding
Xiaoyue Zhang
Xu Li
Hui-Di Feng
ZiYun Lin

Frontiers in Pediatrics

doi 10.3389/fped.2025.1557212

1,817 views