Frontiers in Pharmacology

Original Research

Published on 23 May 2025

Exploring the anti-gastric cancer mechanisms of Diosgenin through integrated network analysis, bioinformatics, single-cell sequencing, and cell experiments

in Ethnopharmacology

Zhangjun Yun
Qianru Yang
Chengyuan Xue
Yang Shen
Liyuan Lv
Suicai Mi
Li Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1600960

536 views

Systematic Review

Published on 23 May 2025

Therapeutic efficacy and mechanisms of Xuebijing in Acinetobacter baumannii infection based on meta-analysis and integrated pharmacology approaches

in Ethnopharmacology

Jiaqi Li
Yihan Sun
Hao Wen
Boying Xiao
Jianming Wang
Ziqi Li
Lei Wang
Meiyu Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598359

624 views

Review

Published on 23 May 2025

Research progress in the treatment of non-scarring alopecia: mechanism and treatment

in Experimental Pharmacology and Drug Discovery

Rui-Xian Guo
Yong-Kang Zhao
Ke-Jian Hu
Kun-Mu Jia
Wei Shi
Yan-Xiao Yi
Hai-Ying Gong
Jia-Bo Wang
Yuan Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544068

873 views

Original Research

Published on 23 May 2025

Development and validation of a machine-learning model for the risk of potentially inappropriate medications in elderly stroke patients

in Drugs Outcomes Research and Policies

Xiaodan Yang
Qianqian Ye
Mengxiang Zhang
Yuewei Xu
Manqin Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565420

768 views

Original Research

Published on 23 May 2025

Identification of biomarkers and potential drug targets in DFU based on fundamental experiments and multi-omics joint analysis

in Experimental Pharmacology and Drug Discovery

Xudong Xin
Haidong Zhou
Song Huang
Wenzhao Zhang
Jiahou Xu
Wei Wang
Jihua Wei
Liqing Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561179

792 views

Original Research

Published on 23 May 2025

Ophiopogonin D mitigates doxorubicin-induced cardiomyocyte ferroptosis through the β-catenin/GPX4 pathway

in Ethnopharmacology

Yanping Lei
Lewu Xu
Rui Liu
Yue Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586937

473 views

Original Research

Published on 23 May 2025

A sex-sensitive LC-MS/MS method with isotopic internal standard for prazosin bioequivalence: bridging precision medicine and generic drug policy in China

in Drugs Outcomes Research and Policies

Hui Chen
Junping Guo
Zhenyu Zhu
Xiaomei Huang
Jincai Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592731

550 views

Systematic Review

Published on 23 May 2025

Cost-effectiveness of dapagliflozin for the treatment of heart failure: a systematic review

in Drugs Outcomes Research and Policies

Zehui Jiang
Dong xiao Chen
Cai Xiao
Ying Fu
Jun Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572289

725 views

Original Research

Published on 23 May 2025

Pharmacokinetic and pharmacodynamic analyses of nafamostat in ECMO patients: comparing central vein and ECMO machine samples

in Drug Metabolism and Transport

Dong Hwan Lee
Jae Ha Lee
Ji Hoon Jang
Yong Kyun Kim
Gaeun Kang
So Young Jung
Minyoung Her
Hang Jea Jang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1541131

551 views

Review

Published on 23 May 2025

Current paradigm and futuristic vision on new-onset diabetes and pancreatic cancer research

in Pharmacology of Anti-Cancer Drugs

Russell Moreland
Abigail Arredondo
Anupam Dhasmana
Swati Dhasmana
Shabia Shabir
Asfia Siddiqua
Bonny Banerjee
Murali M. Yallapu
Stephen W. Behrman
Subhash C. Chauhan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543112

849 views

Original Research

Published on 23 May 2025

Perioperative dexmedetomidine effects on delirium in elderly patients after noncardiac surgery: A retrospective propensity score analysis

in Drugs Outcomes Research and Policies

Hong-Wei Wang
Qin-Jun Chu
Ze-Fei Zhu
Ming Cheng
Ze-Ping Li
Liang Zang
Long He
Lin-Na Chen
Qian He
Jian-Jun Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578233

503 views

Original Research

Published on 23 May 2025

Prediction of early mucosal healing of Crohn’s disease after treatment with biologics- a novel nomogram based on radiomics and clinical risk factors

in Drugs Outcomes Research and Policies

Linlin Huang
Hui Li
Shuo Wang
Ying Ren

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586300

480 views

Brief Research Report

Published on 23 May 2025

Dynamic star allele definitions in Pharmacogenomics: impact on diplotype calls, Phenotype predictions and statin therapy recommendations

in Pharmacogenetics and Pharmacogenomics

Sven van der Maas
Simon Denil
Brigitte Maes
Gökhan Ertaylan
Pieter-Jan Volders

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584658

615 views

Review

Published on 23 May 2025

Advances in the treatment of lower-extremity ischemia-reperfusion injury

in Cardiovascular and Smooth Muscle Pharmacology

Jin Peng
Tang Deng
Xunkai Wang
Jinxi Liang
Jiangpeng Wu
Binglong Li
Jun Lv
Shenmei Wu
Shijie Zhong
Chen Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1576091

539 views

Review

Published on 23 May 2025

A potential herbal component for the future treatment of fatty liver disease: Geniposide from gardenia

in Gastrointestinal and Hepatic Pharmacology

Qinyao Zhang
Ziyan Li
Lina Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610676

624 views

Original Research

Published on 23 May 2025

No significant gender differences in driving-related skills following alcohol mixed with energy drinks during an experimental binge-drinking episode

in Experimental Pharmacology and Drug Discovery

Olga Hladun
Esther Papaseit
Lourdes Poyatos
Soraya Martín
Ana Pilar Pérez-Acevedo
Ana Maria Barriocanal
Tatiana Bustos-Cardona
Susana Malumbres
Rafael De La Torre
Klaus Langohr

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1581229

748 views