Frontiers in Pharmacology

Original Research

Published on 27 Jun 2025

Simplified flow cytometry-based assay for rapid multi-cytokine profiling and machine-learning-assisted diagnosis of inflammatory diseases

in Translational Pharmacology

Qiang Quan
Xuegui Ju
Guangmei Li
Lu Ye
Sichong Ren
Shuxin Yang
Rui Zhang
Hui Wang
Ruyue Lin
Luoting Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1594141

1,151 views

Review

Published on 27 Jun 2025

Critical role of LncRNA in sepsis-associated acute kidney injury

in Renal Pharmacology

Lingjian Jin
Jian Liao
Litong Jin
Chunyan Chen
Feng Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627253

1,146 views

Original Research

Published on 27 Jun 2025

Glycyrrhiza uralensis Fisch. suppresses cell migration via ROS and JAK/STAT signalling pathways in Drosophila

in Pharmacology of Anti-Cancer Drugs

Fangfei Zhou
Qingge Lu
Lingyu Kong
Sitong Wang
Haixia Zhang
Meng Zhao
Yue Hu
Fanwu Wu
Chenxi Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549920

1,074 views

Original Research

Published on 27 Jun 2025

Design, synthesis and antiproliferative activity of novel colchicine derivatives: selective inhibition of melanoma cell proliferation

in Experimental Pharmacology and Drug Discovery

Puneet Kumar
Tusharika Kotra
Waseem I. Lone
Yassir Arfath
Harshita Tiwari
Ashutosh Kumar Shukla
Zabeer Ahmed
Sheikh Rayees
Jasha Momo H. Anal

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528235

1,391 views

Review

Published on 27 Jun 2025

A review of natural compounds to regulate platelet aggregation: molecular mechanism and research advance

in Ethnopharmacology

Yi Hou
Hong Li
Luochen Zhu
Yue Li
Yue Zeng
Tian Quan
Zhangqiang Xiang
Yue Zhang
Yuan Bian
Yuxun Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537776

1,615 views

Original Research

Published on 27 Jun 2025

Protective effects of Salubrinal against H2O2-induced muscle wasting via eIF2α/ATF4 signaling pathway

in Inflammation Pharmacology

Siming Lin
Jingying Wu
Guili Lian
Weibin Wu
Weixiao Chen
Ai Chen
Li Luo
Liangdi Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1607606

1,133 views

Review

Published on 27 Jun 2025

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases

in Neuropharmacology

Shijun Bi
Shibing Liu
Kunyuan Zhu
Dandan Gao
Ligang Chen
Chunyong Yu
Guobiao Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1606146

1,845 views

Original Research

Published on 27 Jun 2025

Uncovering the molecular targets of phytocannabinoids: mechanistic insights from inverse molecular docking fingerprint approaches

in Experimental Pharmacology and Drug Discovery

Vid Ravnik
Marko Jukič
Veronika Furlan
Uroš Maver
Jan Rožanc
Urban Bren

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1611461

1,605 views

Original Research

Published on 27 Jun 2025

Design and screening of novel 1,2,4-Triazole-3-thione derivatives as DCN1 inhibitors for anticardiac fibrosis based on 3D-QSAR modeling and molecular dynamics

in Experimental Pharmacology and Drug Discovery

Wengong Bian
Yaxin Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590711

823 views

Review

Published on 27 Jun 2025

Bridging traditional Chinese medicine and Alzheimer’s disease: the pivotal role of gut microbiota in multitarget therapeutic mechanisms

in Ethnopharmacology

Weidong Wu
Tianwei Meng
Lichao Han
Fangfang Jin
Pengfei Han
Yanyan Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630205

1,303 views

Original Research

Published on 27 Jun 2025

Pharmacovigilance-related events, disease burden and overall efficiency of care in european countries, 1990-2021

in Pharmacoepidemiology

Lin Yin
Shuzhi Lin
Qian Liu
Xiaoying Zhu
Wei Liu
Yifang Shen
Zimeng Li
Bianling Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592957

863 views

Original Research

Published on 26 Jun 2025

Drug-associated hearing impairment in children: a disproportionality analysis of the FDA adverse event reporting system

in Pharmacoepidemiology

Jinfeng Liu
Junyi Tan
Qinli Xiao
Yingtao Bai
En Chang
Chun Su
Yuxun Wei
Hu Zhong
Wei Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532461

1,576 views

Original Research

Published on 26 Jun 2025

Pedunculoside targets P2X7R to protect against myocarditis by regulating the NLRP3/PIP2/MAPK signaling pathway

in Cardiovascular and Smooth Muscle Pharmacology

Youqiong Zhuo
Jia He
Qin-Qin Wang
Yuntian Xiao
Xiaoyun Xie
Lina Liu
Shilin Yang
Jingjing Li
Renyikun Yuan
Hongwei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1589298

1,202 views

Review

Published on 26 Jun 2025

Ethnobotany, phytochemistry, pharmacology and toxicity of Hagenia abyssinica (Bruce) J.F.Gmel.: a review

in Ethnopharmacology

Guohui Shi
Linlin Ni
Yang Zhang
Zhizi Qu
Xiaoni Kong
Honglei Zhou
Yan Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593724

1,081 views

Original Research

Published on 26 Jun 2025

i-DENV: development of QSAR based regression models for predicting inhibitors targeting non-structural (NS) proteins of dengue virus

in Experimental Pharmacology and Drug Discovery

Sakshi Gautam
Anamika Thakur
Manoj Kumar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605722

1,682 views

Systematic Review

Published on 26 Jun 2025

Compound Xuanju capsules combined with phosphodiesterase-5 inhibitors as a new strategy for erectile dysfunction: a meta-analysis and trial sequential analysis

in Ethnopharmacology

Ronghui Li
Min Liao
Yunfeng Yu
Bing Guo
Rong Yu
Qinghu He
Guomin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537789

1,242 views