Frontiers in Pharmacology

Original Research

Accepted on 29 Aug 2025

Pharmacological Effects and Phytochemical Profile of Methanolic Odontosoria biflora (Kaulf.) C.Chr. [Lindsaeaceae] Extract in Caenorhabditis elegans Models of Parkinson's Disease

in Ethnopharmacology

Meysam Hamel Darbandi
Leslie Michelle M. Dalmacio
Jose Ma. Moncada Angeles

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1662877

973 views

Systematic Review

Published on 29 Aug 2025

Biochemical changes associated with non-alcoholic fatty liver disease in response to berberine treatment: a systematic review and meta-analysis of clinical and preclinical research

in Gastrointestinal and Hepatic Pharmacology

Wenyu Zhu
Lele Yang
Yufan Dai
Hanyang Wang
Jiaxuan Zhou
Lina Xia
Tao Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1460643

1,327 views

Review

Published on 29 Aug 2025

Emerging opportunities to treat drug-resistant breast cancer: Discovery of novel small-molecule inhibitors against different targets

in Pharmacology of Anti-Cancer Drugs

Ruixian Chen
Zhilan Zhou
Xiangyue Meng
Yi Lei
Yuxi Wang
Yanyan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578342

1,431 views

Original Research

Published on 29 Aug 2025

Deciphering the role of myofibroblasts in microvascular invasion of hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Xiang Liu
Jiangyang Pan
Lijia Wang
Qiao Xie
Tianbo Fan
Qi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1596181

914 views

Systematic Review

Published on 29 Aug 2025

Toxicity profiles of ROS1 tyrosine kinase inhibitors in advanced non-small cell lung cancer: a systematic review and proportional meta-analysis

in Pharmacology of Anti-Cancer Drugs

Bo-Xuan Jiang
Jia-Wei Zeng
Jia-Jia Yan
Li-Yan Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1644034

1,172 views

Original Research

Published on 29 Aug 2025

Icariin ameliorates minimal change disease by regulating the mitochondrial dysfunction pathway: an integrated strategy of network pharmacology, bioinformatics, and experimental validation

in Renal Pharmacology

Hao Wu
Rong Wu
Dian Zhong
Enlai Dai
Li Chen
Guozhong Xue
Xuping Li
Hanyu Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1640822

1,033 views

Correction

Published on 29 Aug 2025

Correction: Efficacy and safety of oral Chinese medicine combined with chemotherapy: a systematic review and network meta-analysis

in Ethnopharmacology

Yuqi Ma
Jia Li
Liyun Liu
Tao Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1646824

677 views

Review

Published on 29 Aug 2025

Barriers and facilitators to non-pharmacological management of metabolic dysfunction-associated steatotic liver disease: a qualitative evidence synthesis

in Gastrointestinal and Hepatic Pharmacology

Yusuf Yilmaz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1615809

1,359 views

Original Research

Published on 29 Aug 2025

c-MYC mRNA destabilization inhibited lethal pancreatic cancer in vivo with significant survival outcomes

in Translational Pharmacology

Jigme P. Dorji
Queenie Chen
Sandali G. Perera
Fizza Aijaz
Petvy Li
Tanjina Sania
Hiroshi Matsui
Chidiebere U. Awah

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630476

1,626 views

Review

Published on 29 Aug 2025

The protective effect and mechanism of dexmedetomidine in inhibiting ferroptosis

in Experimental Pharmacology and Drug Discovery

Xinyi Ren
Ran Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605363

789 views

Original Research

Published on 29 Aug 2025

Zebrafish-based assessment of luteolin’s potential in modulating seizure responses

in Neuropharmacology

Sabrina Ester Schneider
Jefferson Pedroso
Cássia Alves Lima-Rezende
Samara Cristina Mazon
Aline E. dos Santos
Gean Pablo S. Aguiar
Marcelo Lanza
Mariana Appel Hort
J. Vladimir Oliveira
Angelo Piato

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656301

1,095 views

Original Research

Published on 29 Aug 2025

A multi-centre observational cohort study on pharmacogenomic predictors of rosuvastatin discontinuation in a multiethnic population

in Pharmacogenetics and Pharmacogenomics

Mais N. Alqasrawi
Zeina N. Al-Mahayri
Lubna Q. Khasawneh
Areej S. AlBawa’neh
Lilas Dabaghie
Sahar M. Altoum
Dana Hamza
Salahdein Aburuz
Virendra Misra
Gohar Jamil

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656520

1,387 views

Original Research

Published on 29 Aug 2025

Tracking a decade of phase I clinical trials in Italy: trends and insights from national and european registries amid regulatory change

in Drugs Outcomes Research and Policies

Eleonora De Paola
Luna Del Bono
Diego Alejandro Dri
Raffaella Maione
Sandra Petraglia
Fabrizio Galliccia
Giovanni Gori

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661186

1,587 views

Original Research

Published on 29 Aug 2025

Intrathecal silymarin administration improves recovery after compression spinal cord injury: evidence for neuroprotection, antioxidant, and anti-inflammatory action

in Ethnopharmacology

Omar Bahmani
Amir Kiani
Sajad Fakhri
Fatemeh Abbaszadeh
Khodabakhsh Rashidi
Javier Echeverría

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592682

961 views

Review

Published on 29 Aug 2025

The acute adverse health effects of kratom: an evaluation of case reports

in Ethnopharmacology

Sarah Smallets
Sydney Litvin
Grayson Abele
Sarah Kirsh
Dennis Paustenbach

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1620601

1,932 views

Original Research

Published on 29 Aug 2025

Semi-mechanistic population pharmacokinetic model incorporating glutathione S-transferase activity for personalized busulfan dosing in pediatric allogeneic hematopoietic cell transplantation

in Drug Metabolism and Transport

Di Cao
Xiaowen Qian
Ping Wang
Xinyi Zheng
Shan Huang
Zhonglin Wei
Wenjin Jiang
Ling Yu
Xin Jiang
Ying Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632588

924 views