Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Published on 21 Oct 2025

The interaction of AB-680, a CD73 inhibitor, with NBTI, a nucleoside transporter inhibitor, on the adenosinergic control of atrial contractility

in Cardiovascular and Smooth Muscle Pharmacology

Ignac Ovari
Agnes Boglarka Brezniczky
Attila Laczovics
Ervin Berényi
Tamas Erdei
Oluwatofunmi Ojo
Bence Hornok
Bela Juhasz
Zoltan Szilvassy
Judit Zsuga

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683950

168 views

Original Research

Published on 20 Oct 2025

Comparative cardiovascular risks of canagliflozin and selective SGLT2 inhibitors in type 2 diabetes

in Cardiovascular and Smooth Muscle Pharmacology

Edy Kornelius
Shih-Chang Lo
Yi-Sun Yang
Yu-Hsun Wang
Chien-Ning Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1686851

311 views

Review

Published on 20 Oct 2025

An overview of insights and updates on TTN mutations in cardiomyopathies

in Cardiovascular and Smooth Muscle Pharmacology

Sarmistha Saha
Gazmend Temaj
Pelin Telkoparan-Akillilar
Silvia Chichiarelli
Luciano Saso

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1668544

426 views

Original Research

Published on 17 Oct 2025

Empagliflozin’s cardioenergetic protective effects through PPARα pathway modulation in heart failure

in Cardiovascular and Smooth Muscle Pharmacology

Hua Wei
Menghua Yin
Junshun Chang
Bo Feng
Qin Zhou
Xirong Li
Ping Wu
Xiaoshan Guo
Siyuan Chen
Bao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1636810

894 views

Original Research

Accepted on 15 Oct 2025

Efficacy and Influencing Factors Analysis of SGLT2 Inhibitors in Treating Heart Failure Following Acute Myocardial Infarction

in Cardiovascular and Smooth Muscle Pharmacology

Haiping Du
Hui Xu
Jinwei Bao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1693420

280 views

Original Research

Published on 14 Oct 2025

Identification of an anti-inflammatory action of exosome release in P2Y4 loss-mediated cardioprotection

in Cardiovascular and Smooth Muscle Pharmacology

Esteban Diaz Villamil
Paul Rouvier
Michael Horckmans
Lucas De Roeck
Erika Hendrickx
Louise Conrard
Didier Communi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664015

440 views

Original Research

Accepted on 13 Oct 2025

Risk of post-polypectomy bleeding and thromboembolic events during colonoscopy in patients on continued or interrupted antiplatelet therapy: a pooled analysis

in Cardiovascular and Smooth Muscle Pharmacology

Nan-Nan Shen
Jun-Hong Ma
Hua Qian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660871

118 views

Review

Published on 13 Oct 2025

Diabetic cardiomyopathy and COVID-19: intersecting pathways and amplified cardiovascular risk

in Cardiovascular and Smooth Muscle Pharmacology

Swati Prakash
Priyanka Choudhury
Shradha Bisht

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683159

1,146 views

Case Report

Accepted on 10 Oct 2025

Clopidogrel-induced Drug-Induced Hypersensitivity Syndrome Following Percutaneous Coronary Intervention: A Case Report of Therapeutic Dilemma and Management Strategy

in Cardiovascular and Smooth Muscle Pharmacology

Sikun Wang
Jiang Zhou
Yuanhua Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695177

190 views

Original Research

Published on 09 Oct 2025

Forced intensity-controlled endurance training on a small-animal treadmill machine inducing murine cardiac hypertrophy: insights and comparison to voluntary running models

in Cardiovascular and Smooth Muscle Pharmacology

Maximillian Fischer
Agus Simahendra
Tobias Straub
Stefan Brunner
Bartolo Ferraro
Ludwig T. Weckbach

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682751

1,054 views

Review

Published on 09 Oct 2025

The crosstalk between mitochondrial dysfunction and fatty acid metabolism in heart failure: mechanisms and therapeutic strategies

in Cardiovascular and Smooth Muscle Pharmacology

Min Wang
Zheqin Zhu
Xuan He
Sisi Dai
Rongzhen Liu
Jianhe Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1679085

2,111 views

Mini Review

Published on 09 Oct 2025

Tanshinone I, tanshinone IIA, and cryptotanshinone: key bioactive components modulating vascular smooth muscle cell function

in Cardiovascular and Smooth Muscle Pharmacology

Jixin Li
Wenru Wang
Hongbo Huang
Ruiling Zhou
Zhenyu Yang
Zhijie Cui
Zelong Niu
Shengnan Shi
Peili Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1688338

533 views

Original Research

Published on 08 Oct 2025

Protective effects of avenanthramide-C against cisplatin-induced cardiotoxicity in rats by attenuating oxidative stress, inflammatory cytokines, and modulating p62–Keap1–Nrf2 pathway

in Cardiovascular and Smooth Muscle Pharmacology

Maha Abdulrahman Aldubayan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694060

833 views

Original Research

Published on 08 Oct 2025

Candesartan preserves aortic structure and function in cisplatin-treated rats by upregulating SIRT1/Nrf2/HO-1 signaling and suppressing oxidative stress, TLR-4/NF-κB signaling, and necroptosis

in Cardiovascular and Smooth Muscle Pharmacology

Ayman M. Mahmoud
Sulaiman M. Alnasser
Omnia A. M. Abd El-Ghafar
Reem S. Alruhaimi
Hanan S. Althagafy
Ahmed M. Atwa
Emad H. M. Hassanein

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678921

1,257 views

Review

Accepted on 06 Oct 2025

SIRT1: The First key to unlocking the mystery of cardiovascular diseases

in Cardiovascular and Smooth Muscle Pharmacology

Dinislam Khuzin
Muneer Ahmed Khoso
Valeriy Kataev
Svetlana Meshcheryakova
Heng Liu
Ling Liu
Madi Guo
Song Wang
Han Lou
Yong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1668718

127 views

Original Research

Published on 01 Oct 2025

Chlorogenic acid modulates mitochondrial damage and mitophagy to repair injured myocardial tissue and cells

in Cardiovascular and Smooth Muscle Pharmacology

Hao Ling
Yu Zhang
Chunli Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658090

1,902 views