Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Published on 01 Oct 2025

Chlorogenic acid modulates mitochondrial damage and mitophagy to repair injured myocardial tissue and cells

in Cardiovascular and Smooth Muscle Pharmacology

Hao Ling
Yu Zhang
Chunli Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658090

737 views

Original Research

Accepted on 30 Sep 2025

Quantitative assessment of the usability of electromechanical human-based modelling and simulation to replace Langendorff isolated rabbit heart experiments in the preclinical setting

in Cardiovascular and Smooth Muscle Pharmacology

Maxx Holmes
Hector Martinez-Navarro
Marcel Mohr
Jean-Marie Chambard
Veronique Ballet
Eva Vermersch
Ambroise Garry
Friedemann Schmidt
Blanca Rodriguez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671199

Original Research

Accepted on 30 Sep 2025

The interaction of AB-680, a CD73 inhibitor, with NBTI, a nucleoside transporter inhibitor, on the adenosinergic control of atrial contractility

in Cardiovascular and Smooth Muscle Pharmacology

Ignác Óvári
Agnes Boglarka Brezniczky
Attila Laczovics
Ervin Berényi
Tamas Erdei
Tofunmi Ojo
Bence Hornok
Bela Juhász
Zoltan Szilvassy
Judit Zsuga

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683950

Original Research

Published on 30 Sep 2025

Thymidine exerts anti-doxorubicin-induced cardiomyopathy effect through the regulation of the PPAR signaling pathways and ferroptosis pathways

in Cardiovascular and Smooth Muscle Pharmacology

Bin Li
Qifei Wang
Jiashuo Zhou
Peihai Li
Chen Sun
Qing Xia
Yun Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524167

1,507 views

Correction

Published on 30 Sep 2025

Correction: An update of the molecular mechanisms underlying anthracycline induced cardiotoxicity

in Cardiovascular and Smooth Muscle Pharmacology

Sicong Xie
Yuwei Sun
Xuan Zhao
Yiqun Xiao
Fei Zhou
Liang Lin
Wei Wang
Bin Lin
Zun Wang
Zixuan Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708198

725 views

Mini Review

Accepted on 29 Sep 2025

Tanshinone I, Tanshinone IIA, and Cryptotanshinone: Key Bioactive Components Modulating Vascular Smooth Muscle Cell Function

in Cardiovascular and Smooth Muscle Pharmacology

Jixin Li
Wenru Wang
Hongbo Huang
Ruiling Zhou
Zhenyu Yang
Zhijie Cui
Zelong Niu
Shengnan Shi
Peili Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1688338

192 views

Review

Accepted on 29 Sep 2025

Diabetic Cardiomyopathy and COVID-19: Intersecting Pathways and Amplified Cardiovascular Risk

in Cardiovascular and Smooth Muscle Pharmacology

Swati Prakash
Priyanka Choudhury
Shradha Bisht

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683159

272 views

Review

Published on 29 Sep 2025

Mitochondrial dysfunction as a therapeutic nexus in HFpEF: therapeutic target and pharmacological advances

in Cardiovascular and Smooth Muscle Pharmacology

Tian Yue
Dezhi Zheng
Jian He
Shiqiang Xiong
Junbo Xu
Jun Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1676988

999 views

Original Research

Accepted on 26 Sep 2025

Empagliflozin's Cardioenergetic Protective Effects through PPARα Pathway Modulation in Heart Failure

in Cardiovascular and Smooth Muscle Pharmacology

Hua Wei
Menghua Yin
Junshun Chang
Bo Feng
Qin Zhou
Xirong Li
Ping Wu
Xiaoshan Guo
Siyuan Chen
Bao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1636810

608 views

Review

Published on 26 Sep 2025

Copper homeostasis and cuproptosis in myocardial infarction: molecular mechanisms, treatment strategies and potential therapeutic targets

in Cardiovascular and Smooth Muscle Pharmacology

Zhen Shen
Zhichao Liu
Siqi Cai
Huanjie Fu
Yongkang Gan
Xiaofeng Li
Xizhen Wang
Chang Liu
Wenjia Ma
Jinhong Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1525585

1,382 views

Case Report

Accepted on 25 Sep 2025

Exercise-Associated Changes of Leukocyte Gene Expression in Statin-Associated Myopathy – A Case Study

in Cardiovascular and Smooth Muscle Pharmacology

Galyna Bondar
Abhinandan Das Mahapatra
Irina Silacheva
Adrian Hairapetian
Thomas Vu
Stephanie Su
Ananya Katappagari
Liana Galan
Joshua Chandran
Ruben Adamov

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695543

1,764 views

Review

Accepted on 25 Sep 2025

The crosstalk between mitochondrial dysfunction and fatty acid metabolism in heart failure: Mechanisms and therapeutic strategies

in Cardiovascular and Smooth Muscle Pharmacology

Min Wang
Zheqin Zhu
Xuan He
Sisi Dai
Rongzhen Liu
Jianhe Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1679085

1,695 views

Review

Published on 25 Sep 2025

Rivaroxaban versus low-molecular-weight heparin for venous thromboembolism prophylaxis: a systematic review of efficacy, safety, and cost-effectiveness

in Cardiovascular and Smooth Muscle Pharmacology

Bin Li
Ling Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1652779

1,222 views

Original Research

Accepted on 22 Sep 2025

Forced intensity-controlled endurance training on a small-animal treadmill machine inducing murine cardiac hypertrophy: insights and comparison to voluntary running models

in Cardiovascular and Smooth Muscle Pharmacology

Maximilian Gustav Fischer
Agus Simahendra
Tobias Straub
Stefan Brunner
Bartolo Ferraro
Ludwig Weckbach

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682751

515 views

Original Research

Accepted on 22 Sep 2025

Protective effects of avenanthramide-C against cisplatin-induced cardiotoxicity in rats by attenuating oxidative stress, inflammatory cytokines, and modulating p62– Keap1–Nrf2 pathway

in Cardiovascular and Smooth Muscle Pharmacology

Maha Aldubayan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694060

497 views

Original Research

Published on 22 Sep 2025

Evaluation of left ventricular systolic function in different subtypes of pediatric acute lymphoblastic leukemia: a case-control study based on two-dimensional speckle tracking

in Cardiovascular and Smooth Muscle Pharmacology

Yanfeng Yang
Chunyan Fu
Kun Shi
Yonghong Guo
Peng Shi
Hanmin Liu
Ling Gu
Ying Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669049

1,244 views