Frontiers in Pharmacology | Gastrointestinal and Hepatic Pharmacology

Original Research

Accepted on 22 Aug 2025

The Role of Dried Ginger in Gastritis: A Comprehensive Multi-Omics Analysis of Its Healing Properties

in Gastrointestinal and Hepatic Pharmacology

Xiujuan Yang
Jiajia Wang
Yaxing Wang
Qingyun Ji
Shuo Li
Yihong Tian
Zhijun Yang
Yuefeng Li
Yunxiang Hai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619487

163 views

Systematic Review

Accepted on 21 Aug 2025

Comparative Gastrointestinal Adverse Effects of GLP-1 Receptor Agonists and Multi-Target Analogs in Type 2 Diabetes: A Bayesian Network Meta-Analysis in Type 2 Diabetes: A Bayesian Network Meta-Analysis

in Gastrointestinal and Hepatic Pharmacology

Xingmiao Xie
Shuiyuan Yang
Shuzhen Deng
Yuying Liu
Zhibin Xu
Binghong He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1613610

114 views

Original Research

Published on 20 Aug 2025

Clinical efficacy and regulatory mechanisms of Shi Pi Zeng Ye formula in treating functional constipation comorbid with depression: integrating clinical observation, mass spectrometry, bioinformatics, and molecular docking

in Gastrointestinal and Hepatic Pharmacology

Ling Yao
Xiaoqiang Jia
Yufei Li
Haixia Li
Zhuhui Zhang
Longfang Quan
Qiuling Liu
Jie Dai
Xuedi Lei
Huashang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1645277

422 views

Review

Accepted on 19 Aug 2025

Barriers and facilitators to non-pharmacological management of metabolic dysfunction-associated steatotic liver disease: a qualitative evidence synthesis

in Gastrointestinal and Hepatic Pharmacology

Yusuf YILMAZ

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1615809

221 views

Original Research

Accepted on 18 Aug 2025

Berberine Protects Against Gefitinib-Induced Liver Injury by Inhibiting the HMGB1/TLR4/NF-κB Pathway

in Gastrointestinal and Hepatic Pharmacology

Qiongyin Zhang
Na Li
Xue Ma
Yue Qiu
Chao Li
Ya Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1645634

146 views

Original Research

Accepted on 18 Aug 2025

Ramucirumab plus paclitaxel as switch maintenance in patients with advanced HER2-negative gastric or gastro-oesophageal junction cancer: a cost-effectiveness analysis

in Gastrointestinal and Hepatic Pharmacology

Jiefeng Luo
Zhengxiong Li
Qiong Du
Jiyong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616826

231 views

Systematic Review

Published on 15 Aug 2025

Comparison of ciprofol and propofol for endoscopic retrograde cholangio-pancreatography anesthesia: a systematic review and meta-analysis

in Gastrointestinal and Hepatic Pharmacology

Kai Wu
Min Liao
Juan Deng
Yunfeng Yu
Yuman Yin
Xinyu Yang
Rong Yu
Zhenjie Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592781

493 views

Original Research

Accepted on 14 Aug 2025

Ruxolitinib Alleviates DSS-Induced Acute Ulcerative Colitis by Inhibiting STAT1 Phosphorylation and Reducing MDSC Infiltration

in Gastrointestinal and Hepatic Pharmacology

Lu Xu
Fangyue Xu
Vincent Kam Wai Wong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572534

124 views

Original Research

Published on 14 Aug 2025

Exercise ameliorates hepatic lipid accumulation via upregulating serum PRL and activating hepatic PRLR-mediated JAK2/STAT5 signaling pathway in NAFLD mice

in Gastrointestinal and Hepatic Pharmacology

Jia Fan
Kaidi Nie
Xiaobing Liu
Jiao Liu
Binghua Shao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1647231

319 views

Systematic Review

Accepted on 13 Aug 2025

Efficacy and safety of fruquintinib in the treatment of colorectal cancer: a systematic review and meta-analysis of studies in China

in Gastrointestinal and Hepatic Pharmacology

Yuan Feng
Yu Shu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590782

265 views

Original Research

Accepted on 13 Aug 2025

Efficacy of Indomethacin for the Prevention of Post-ERCP Pancreatitis: A Comprehensive Meta-Analysis of Randomized Controlled Trials

in Gastrointestinal and Hepatic Pharmacology

Fu Tian
Zhicheng Huang
Hayat Khizar
Kai Qiu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675615

107 views

Original Research

Accepted on 13 Aug 2025

Mechanistic Study on the Restoration of Intestinal Barrier Integrity and Alleviation of Inflammatory Bowel Disease by Rhynchophylline via the AhR-NR4A1 Pathway

in Gastrointestinal and Hepatic Pharmacology

Xuwen Mao
Lufeng Cheng
Yu Liu
Yuche Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1629012

159 views

Systematic Review

Published on 11 Aug 2025

Potential of ciprofol as an alternative to propofol in elderly patients undergoing gastrointestinal endoscopy: a meta-analysis and trial sequential analysis

in Gastrointestinal and Hepatic Pharmacology

Yunfeng Yu
Min Liao
Juan Deng
Xinyu Yang
Yuman Yin
Zhenjie Liu
Guomin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1644182

335 views

Systematic Review

Accepted on 08 Aug 2025

Biochemical Changes Associated with Non-Alcoholic Fatty Liver Disease in Response to Berberine Treatment: A Systematic Review and Meta-Analysis of Clinical and Preclinical Research

in Gastrointestinal and Hepatic Pharmacology

Wenyv Zhu
Lele Yang
Yufan Dai
Hanyang Wang
Jiaxuan Zhou
Lina Xia
Tao Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1460643

149 views

Original Research

Published on 08 Aug 2025

Hydrogen gas (H2) delivered by intraperitoneal injection alleviated methionine- and choline-deficient diet-induced metabolic dysfunction–associated steatotic liver disease in mice via inhibiting GSDMD- and GSDME-mediated pyroptosis

in Gastrointestinal and Hepatic Pharmacology

Yun Chen
Kangrong Wang
Wenhai Guo
Chengqin Lu
Wenting Suo
Qiuling Li
Yao Deng
Xinling Chen
Min Dai
Xiaodong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575106

670 views

Original Research

Published on 06 Aug 2025

A pharmacovigilance study of the association between linaclotide/plecanatide and muscle spasms based on food and drug administration adverse event reporting system

in Gastrointestinal and Hepatic Pharmacology

Xue Fan
Yuan Li
Xiangchun Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1635792

781 views