Frontiers in Pharmacology | Neuropharmacology

Mini Review

Published on 28 Apr 2025

The prospective approach for aptamers applied in the treatment and molecular diagnostics of ischemic stroke

in Neuropharmacology

Wenfeng Li
Junyi Wu
Zijian Hu
Jixuan Zhang
Guangming Ye
Fengling Luo
Zhikun Zeng
Yi Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553337

1,169 views

Original Research

Published on 28 Apr 2025

Administration of chiglitazar reverses chronic stress-induced depressive-like symptoms in mice via activation of hippocampal PPARα and BDNF

in Neuropharmacology

Jiu-Jian Zhou
Jie Zhao
Shang-Yan Gao
Yuan-yuan Gao
Cheng Chen
Yi Ding
Zhong-hua Wu
Pu-Jian Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587399

1,185 views

Review

Published on 28 Apr 2025

Current insights and prospects for the pathogenesis and treatment of clinical manifestations associated with Down syndrome through neurotransmitter, inflammatory, and oxidative stress pathways

in Neuropharmacology

Fawaz Alasmari
Ashfaq Ahmad
Sary Alsanea
Alaa M. Hammad
Walid Al-Qerem

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592277

1,224 views

Mini Review

Published on 28 Apr 2025

The role of glutamate dehydrogenase in the ageing brain

in Neuropharmacology

Tao Zhou
Haichuan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586655

1,044 views

Editorial

Published on 25 Apr 2025

Editorial: Interplay between chronic pain and affective-cognitive alterations: shared neural mechanisms, circuits, and treatment

in Neuropharmacology

Luca Posa
Danilo de Gregorio
Serena Boccella
Kelly Smart

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605670

887 views

Systematic Review

Published on 25 Apr 2025

Effectiveness and safety of single anti-seizure medication as adjunctive therapy for drug-resistant focal epilepsy based on network meta-analysis

in Neuropharmacology

Nian-Jia Deng
Xin-Yi Li
Zhi-Xin Zhang
Chen-Yang Xian-Yu
Yu-Ting Tao
Yu-Tong Ma
Hui-Jun Li
Teng-Yu Gao
Xin Liu
Jie Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500475

2,035 views

Original Research

Published on 25 Apr 2025

Suicidal thoughts and behaviors associated with fluoroquinolone antibiotics: a real-world pharmacovigilance analysis

in Neuropharmacology

Lijuan Yang
Congqin Chen
Lingqing Ding
Tingting Lu
Xiwen Li
Jie Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556159

1,473 views

Mini Review

Published on 25 Apr 2025

Trace amine-associated receptors as potential targets for the treatment of anxiety and depression

in Neuropharmacology

Zelong Li
Luoting Wan
Jing Dong
Jinquan Li
Jianfeng Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598048

1,184 views

Original Research

Published on 25 Apr 2025

In vitro and in-vivo exploration of physostigmine analogues to understand the mechanistic crosstalk between Klotho and targets for epilepsy

in Neuropharmacology

Mansi Dahalia
Haya Majid
Mohd Junaid Khan
Akshat Rathi
Mohd Ashif Khan
Imran Ahmd Khan
Mohammed Samim
Sayeed Ur Rehman
Md Salik Noorani
Divya Vohora

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580943

1,638 views

Original Research

Published on 25 Apr 2025

Edaravone dexborneol protected neurological function by targeting NRF2/ARE and NF-κB/AIM2 pathways in cerebral ischemia/reperfusion injury

in Neuropharmacology

Hui Zhang
Can Zhu
Xingyu Zhou
Laifa Wang
Ling Deng
Binsheng He
Jianming Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1581320

1,564 views

Original Research

Published on 24 Apr 2025

Multi-target neuroprotection by dl-PHPB in APP/PS1 mice: a proteomic analysis

in Neuropharmacology

Yingni Sun
Guoliang Bai
Kangmin Yang
Yong Feng
Hongmei Sun
Li Xian
Hongwei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554168

1,090 views

Original Research

Published on 24 Apr 2025

Exploring the diagnostic potential of IL1R1 in depression and its association with lipid metabolism

in Neuropharmacology

Yao Gao
Xiao-Na Song
Nan Zhang
Huang-Hui Liu
Jian-Zhen Hu
Xin-Zhe Du
Guo-Hua Song
Sha Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519287

1,384 views

Systematic Review

Published on 24 Apr 2025

Tailoring dual antiplatelet therapy for stroke prevention: a meta-analysis of timing, duration, regimen, and stroke subtypes

in Neuropharmacology

Naif M. Alhawiti
Sherouk Fouda
Naser D. Alotaibi
Hassan A. Madkhali
Fahad K. Alsharef
Jamal M. Alhawiti
Ashraf El-Metwally

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516402

1,706 views

Original Research

Published on 23 Apr 2025

Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression

in Neuropharmacology

Sarah Delcourte
Amel Bouloufa
Renaud Rovera
Elie Brunet
Hiep D. Le
April E. Williams
Satchidananda Panda
Rihab Azmani
Olivier Raineteau
Ouria Dkhissi-Benyahya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592909

1,288 views

Original Research

Published on 23 Apr 2025

Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors

in Neuropharmacology

Ornella Valenti
Katarzyna Anna Rekawek
Sophie Wieser
Hilal Bulut
Petra Scholze
Stefan Boehm

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534101

1,005 views

Review

Published on 23 Apr 2025

Efficacy, safety, and tolerability of soticlestat (TAK-935) as adjunctive therapy in pediatric patients with dravet syndrome and Lennox–Gastaut syndrome: a meta-analysis of 3 randomized controlled trials

in Neuropharmacology

Zhang Lanlan
Jiang Nana
Wang Chengzhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586098

1,353 views