Frontiers in Pharmacology | Pharmacoepidemiology

Original Research

Accepted on 29 Sep 2025

Integrated Pharmacovigilance of Fentanyl: Multinational Analysis Reveals Novel Safety Signals and Demographic-Specific Risk Profiles

in Pharmacoepidemiology

Junge Zhang
Wenxin Wang
Zihui Lu
Changshun Huang
Hehe Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1700112

274 views

Original Research

Published on 29 Sep 2025

The safety and efficacy of long-term use of calcitonin analogs in the treatment of osteoporosis in the elderly: a pharmacovigilance and RCT meta-analysis

in Pharmacoepidemiology

Lingjie Tan
Bin Sheng
Sui Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514387

1,912 views

Original Research

Published on 25 Sep 2025

Profiles and influencing factors of pulmonary fibrosis associated with biologic and conventional disease-modifying antirheumatic drugs for autoimmune diseases: a disproportionality study based on FAERS and VigiAccess

in Pharmacoepidemiology

Xinyue Zhang
Xinhui Wu
Cheng Luo
Chun Yang
Nan Jia
Jiayi He
Qian Chen
Fei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604895

1,025 views

Systematic Review

Published on 24 Sep 2025

Pharmacogenetics of metamizole-induced agranulocytosis: a systematic review and drug regulation implications

in Pharmacoepidemiology

Giovana Fernanda Santos Fidelis
Carolina Dagli-Hernandez
Romina P. Martinelli
Jefman Efendi Marzuki
Baharuddin Baharuddin
Qun-Ying Yue
Brian Edwards
Eder de Carvalho Pincinato
Patricia Moriel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1624044

855 views

Systematic Review

Published on 24 Sep 2025

Dental safety of short-term doxycycline use in children under 8 years: a systematic review and meta-analysis

in Pharmacoepidemiology

Anusiga Sigamani Rajan
Muthu Gopal
Madhumidha Periyathambi
Vijesh Sreedhar Kuttiatt

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1646638

1,257 views

Original Research

Published on 23 Sep 2025

Impact of post-admission changes in potentially inappropriate medication use on risk of subsequent hospitalization among nursing home residents

in Pharmacoepidemiology

Jing Zhao
Hyunwoo Chae
Young-Mi Ah
Kwanghee Jun
Ju-Yeun Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655681

1,283 views

Original Research

Accepted on 22 Sep 2025

Prevalence and Patterns of Dietary Supplement Use and Potential Drug Interactions Among Older Adults in Saudi Arabia

in Pharmacoepidemiology

Wael Khawagi
Majd M Alghamdi
Laila M Alfalqi
Atheer A Alzahrani
Sara K Alotaibi
Joud J Alsuwat
Fahad Baali
Wadia Alruqayb
Sofa Dewi Alfian
Abdullah A Alshehri

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654337

417 views

Systematic Review

Published on 22 Sep 2025

Efficacy and safety of aldosterone synthase inhibitors for uncontrolled hypertension: a meta-analysis of randomized controlled trials and systematic review

in Pharmacoepidemiology

Yifan Gao
Xu Mu
Xingxue Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664810

1,339 views

Original Research

Published on 22 Sep 2025

Burden of drug use disorders from 1990 to 2021 and projection to 2050 in China: findings from the 2021 global burden of disease study

in Pharmacoepidemiology

Shuzheng Yu
Yanting Chen
Shaohua Huang
Bing Wang
Qingrong Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625873

1,163 views

Original Research

Published on 22 Sep 2025

Tracing the evolution of polypharmacy and contraindicated drug‒drug interactions in people living with HIV in Belgium

in Pharmacoepidemiology

Victoria Lopez Delhoulle
Li-Cécile Destordeur
Nathalie Maes
Karine Fombellida
Majdouline El Moussaoui
Gilles Darcis

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632108

468 views

Brief Research Report

Published on 19 Sep 2025

Single-versus multiple-inhaler triple therapy in patients with COPD in Spain: a retrospective cohort study comparing adherence, persistence, risk of exacerbations and economic outcomes

in Pharmacoepidemiology

M. Asunción González-González
M. Aránzazu Pedrosa-Naudín
Diego Fernández-Lázaro
Isabel Díaz Planelles
F. Javier Álvarez
Eduardo Gutiérrez-Abejón

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642470

1,489 views

Original Research

Published on 17 Sep 2025

Drug-induced agranulocytosis: a disproportionality analysis and umbrella review

in Pharmacoepidemiology

Yajie Lu
Bin Wu
Kunyu Li
Zhonglin Liu
Yuxi Chen
Ting Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1641747

1,280 views

Original Research

Published on 16 Sep 2025

Difference in outcome event coverage between insurance-based and hospital-based databases: a methodological study of diabetes drug use and cardiovascular events in Japan

in Pharmacoepidemiology

Takashi Ando
Tomoaki Hasegawa
Chieko Ishiguro
Jun Komiyama
Toshiki Kuno
Masao Iwagami

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642522

1,426 views

Original Research

Accepted on 15 Sep 2025

A Comprehensive Analysis of Adverse Drug Reactions in 2020-2023: Case Studies

in Pharmacoepidemiology

Jinghui Zhai
Hongzhe Yan
Jinping Zhang
Huiyu Yan
Jie Ma
Sixi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1628347

1,027 views

Original Research

Published on 12 Sep 2025

Global burden and trends of adverse effects of medical treatment, 1990–2021: an analysis from the global burden of disease study 2021

in Pharmacoepidemiology

Keqing Zhang
Yuhai Gao
Yunfei Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655864

1,436 views

Original Research

Published on 09 Sep 2025

Urinary tract infections in women in Catalonia, Spain: a population-based observational cohort study in primary care

in Pharmacoepidemiology

Silvia Fernández-García
Ana Moragas
Maria Giner-Soriano
Rosa Morros
Dan Ouchi
Ana García-Sangenís
Carl Llor

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593910

1,383 views