Frontiers in Pharmacology | Pharmacology of Infectious Diseases

Original Research

Published on 12 Mar 2025

Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma concentration

in Pharmacology of Infectious Diseases

Jun Yang
Mingjie Yu
Yu Gan
Lin Cheng
Ge Yang
Lirong Xiong
Fang Liu
Yongchuan Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1511088

710 views

Original Research

Published on 12 Mar 2025

Exploring the antibacterial potential of Clidemia hirta leaf extract against the pathogenicity of Pseudomonas aeruginosa: in vitro and in silico approaches

in Pharmacology of Infectious Diseases

Vignesh Murugesan
Pargovan Palanivel
Gokul Ramesh
Dwarakesh Ganesh
Helan Soundra Rani Michael
Shivakumar Bandhumy Lingam
Rathish Kumar Sivaraman

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555542

1,082 views

Original Research

Published on 11 Mar 2025

Evaluating the influence MRSA Co-infection on 28-day mortality among sepsis patients: insights from the MIMIC-IV database

in Pharmacology of Infectious Diseases

Yi-Chang Zhao
Jia-Kai Li
Yu-kun Zhang
Zhi-Hua Sun
Rao Fu
Bi-Kui Zhang
Miao Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534107

1,682 views

Brief Research Report

Published on 10 Mar 2025

Omadacycline successfully treated severe Legionella pneumonia after moxifloxacin treatment failure: Case series

in Pharmacology of Infectious Diseases

Biyun Li
Laiyu Liu
Fei Li
Chunmei He
Yuan Chen
Xiaodong Tian
Zhenyu Liu
Weizhen Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559857

1,099 views
1 citation

Systematic Review

Published on 28 Feb 2025

Effectiveness of pharmacological treatments for COVID-19 due to SARS-CoV-2: a systematic literature review

in Pharmacology of Infectious Diseases

Carolina Garcia Vidal
Jonathan González
Carlos Lumbreras
Miguel Salavert
Antonio Castro
Darío Rubio-Rodríguez
Carlos Rubio-Terrés

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1469681

1,575 views

Review

Published on 26 Feb 2025

Calcium phosphate-based anti-infective bone cements: recent trends and future perspectives

in Pharmacology of Infectious Diseases

Xiang Liu
Chaoli Wang
Han Wang
Guoliang Wang
Yong Zhang
Yunfei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522225

1,380 views

Original Research

Published on 26 Feb 2025

Optimisation of cultivation conditions for Bacillus velezensis G7 from mangrove plants and exploration of potential bacteriocins

in Pharmacology of Infectious Diseases

Yang Li
Haotian Ma
Ruixue Pan
Yuner Long
Yining Zhao
Mengbo Yu
Jinju Peng
Yi Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1530043

966 views

Original Research

Published on 26 Feb 2025

Economic impact of individualized antimicrobial dose optimization in the critically ill patient in Spain

in Pharmacology of Infectious Diseases

Santiago Grau
Sonia Luque
Olivia Ferrandez
Adela Benitez Cano
Darío Rubio-Rodríguez
Carlos Rubio-Terrés

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1506109

703 views

Original Research

Published on 24 Feb 2025

Association between statin administration and Clostridium difficile-induced enteritis: a retrospective analysis of the MIMIC-IV database

in Pharmacology of Infectious Diseases

Renli Wang
Rongjun Liu
Hua Wang
Zhaojun Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550378

1,711 views

Case Report

Published on 21 Feb 2025

Treatment of pediatric central nervous system infection caused by carbapenem-resistant Klebsiella pneumoniae with ceftazidime/avibactam, two cases report and literature review

in Pharmacology of Infectious Diseases

Lu Qing
Haiyang Zhang
Xin Pan
Zhongqiang Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532608

1,041 views
1 citation

Original Research

Published on 14 Feb 2025

Model-guided development of pharmacokinetic/pharmacodynamic cut-offs and evaluation of sitafloxacin dosing regimens against target pathogens

in Pharmacology of Infectious Diseases

Hailan Wu
Yi Li
Xin Li
Yaxin Fan
Beining Guo
Xiaofen Liu
Wanzhen Li
Mengting Chen
Yan Chen
Jing Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1476158

865 views

Correction

Published on 14 Feb 2025

Corrigendum: Population pharmacokinetics and dosing optimization of imipenem in Chinese elderly patients

in Pharmacology of Infectious Diseases

Jing Wang
Qiu Fang
Xuemei Luo
Lu Jin
Huaijun Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565995

552 views

Original Research

Published on 04 Feb 2025

in Pharmacology of Infectious Diseases

Muzaffar Kayumov
Parthiban Marimuthu
Jamoliddin Razzokov
Nurkhodja Mukhamedov
Akmal Asrorov
Nodir S. Berdiev
Jamolitdin F. Ziyavitdinov
Ansor Yashinov
Yuliya Oshchepkova
Shavkat Salikhov

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1518463

878 views

Brief Research Report

Published on 22 Jan 2025

PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients

in Pharmacology of Infectious Diseases

Ana Virseda-Berdices
Óscar Brochado-Kith
Juan Berenguer
Juan González-García
Leire Pérez-Latorre
Carmen Busca
Cristina Díez
Rafael Micán
Amanda Fernández-Rodríguez
María Ángeles Jiménez-Sousa

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1436198

1,078 views

Review

Published on 21 Jan 2025

Anti-HSV-1 agents: an update

in Pharmacology of Infectious Diseases

Wenwen Lv
Lei Zhou
Jia Wu
Jishuai Cheng
Yongzhong Duan
Wen Qian

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451083

3,504 views

Systematic Review

Published on 20 Jan 2025

Efficacy and safety of tenofovir and entecavir in patients with chronic hepatitis B-related cirrhosis: a systematic review and meta-analysis

in Pharmacology of Infectious Diseases

Lu Cao
Li Li
Lixing Yang
Nan Zhou
Yu Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507117

1,690 views

376 articles

Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma concentration

Exploring the antibacterial potential of Clidemia hirta leaf extract against the pathogenicity of Pseudomonas aeruginosa: in vitro and in silico approaches

Evaluating the influence MRSA Co-infection on 28-day mortality among sepsis patients: insights from the MIMIC-IV database

Omadacycline successfully treated severe Legionella pneumonia after moxifloxacin treatment failure: Case series

Effectiveness of pharmacological treatments for COVID-19 due to SARS-CoV-2: a systematic literature review

Calcium phosphate-based anti-infective bone cements: recent trends and future perspectives

Optimisation of cultivation conditions for Bacillus velezensis G7 from mangrove plants and exploration of potential bacteriocins

Economic impact of individualized antimicrobial dose optimization in the critically ill patient in Spain

Association between statin administration and Clostridium difficile-induced enteritis: a retrospective analysis of the MIMIC-IV database

Treatment of pediatric central nervous system infection caused by carbapenem-resistant Klebsiella pneumoniae with ceftazidime/avibactam, two cases report and literature review

Model-guided development of pharmacokinetic/pharmacodynamic cut-offs and evaluation of sitafloxacin dosing regimens against target pathogens

Corrigendum: Population pharmacokinetics and dosing optimization of imipenem in Chinese elderly patients

Computational and in vitro evaluation of sumac-derived ©Rutan compounds towards Sars-CoV-2 Mpro inhibition

PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients

Anti-HSV-1 agents: an update

Efficacy and safety of tenofovir and entecavir in patients with chronic hepatitis B-related cirrhosis: a systematic review and meta-analysis