Frontiers in Pharmacology | Pharmacology of Ion Channels and Channelopathies

Review

Published on 04 Jun 2025

Exploring the ER channel protein Sec61: recent advances in pathophysiological significance and novel pharmacological inhibitors

in Pharmacology of Ion Channels and Channelopathies

Jingxin Xin
Keling Yin
Shimeng Li
Peiyuan Gu
Shanshan Shao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580086

187 views

Original Research

Published on 21 May 2025

Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling

in Pharmacology of Ion Channels and Channelopathies

Chun-Wei He
Elva Díaz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568908

398 views

Review

Published on 09 May 2025

The role of transient receptor potential channels in chronic kidney disease-mineral and bone disorder

in Pharmacology of Ion Channels and Channelopathies

Lerong Zhang
Penghao Xu
Lele Hao
Lingling Wang
Yunkai Xu
Chen Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583487

983 views

Review

Published on 30 Apr 2025

Inhibition of NMDA receptors and other ion channel types by membrane-associated drugs

in Pharmacology of Ion Channels and Channelopathies

Elizabeth G. Neureiter
M. Quincy Erickson-Oberg
Aparna Nigam
Jon W. Johnson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561956

1,265 views

Original Research

Published on 29 Apr 2025

Early reduction of skin potassium without sodium accumulation in the pathogenesis of salt sensitivity in primary aldosteronism

in Pharmacology of Ion Channels and Channelopathies

Petr Mlejnek
František Liška
Jan Šilhavý
Kateřina Večerková
Miroslava Šimáková
Michal Pravenec
Theodore W. Kurtz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575972

726 views

Original Research

Published on 22 Apr 2025

Gaussian white noise stimulation as an alternative method to excite sensory neurons

in Pharmacology of Ion Channels and Channelopathies

Thomas Losgott
Klaus W. Schicker
Karlheinz Hilber
Stefan Boehm
Isabella Salzer

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561905

677 views

Original Research

Published on 10 Apr 2025

The venom of Cyriopagopus schmidti spider contains a natural huwentoxin-IV analogue with unexpected improved analgesic potential

in Pharmacology of Ion Channels and Channelopathies

Aurélie Antunes
Jérôme Montnach
Kuldip Khakh
Ludivine Lopez
Baptiste Thomas
Barbara Ribeiro Oliveira-Mendes
Lucie Jaquillard
Denis Servent
Rémy Béroud
Charles J. Cohen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1566312

925 views

Review

Published on 28 Mar 2025

Role of voltage-gated chloride channels in epilepsy: current insights and future directions

in Pharmacology of Ion Channels and Channelopathies

Ming-Ming Ni
Jie-Yu Sun
Zheng-Qian Li
Jin-Chun Qiu
Chun-Feng Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560392

943 views

Review

Published on 26 Mar 2025

Sodium channels as a new target for pain treatment

in Pharmacology of Ion Channels and Channelopathies

Rui Chen
Yiran Liu
Liu Qian
Mingliang Yi
Hong Yin
Shun Wang
Bingbing Xiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573254

2,377 views

Review

Published on 24 Mar 2025

Mechanisms mediating effects of cardiotonic steroids in mammalian blood cells

in Pharmacology of Ion Channels and Channelopathies

Yuri M. Poluektov
Olga D. Lopina
Maria A. Strelkova
Iuliia D. Kuleshova
Alexander A. Makarov
Irina Yu. Petrushanko

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1520927

903 views

Opinion

Published on 21 Mar 2025

When HERG-caused LQT2 encounters antisense oligonucleotide: is exon 6 skipping therapy plausible?

in Pharmacology of Ion Channels and Channelopathies

Zequn Zheng
Yongfei Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535259

718 views

Review

Published on 21 Mar 2025

Recent insights on the impact of SWELL1 on metabolic syndromes

in Pharmacology of Ion Channels and Channelopathies

Mianhong Qin
Xuejie Yi
Ziqiang Duan
Bo Chang
Tao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552176

1,128 views

Original Research

Published on 07 Mar 2025

Selenium reduces oxaliplatin induced neuropathic pain: focus on TRPV1

in Pharmacology of Ion Channels and Channelopathies

Bilal Çiğ

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549190

1,425 views

Original Research

Published on 28 Feb 2025

Administration of the KCa channel activator SKA-31 improves endothelial function in the aorta of atherosclerosis-prone mice

in Pharmacology of Ion Channels and Channelopathies

O. Daniel Vera
Ramesh C. Mishra
Rayan Khaddaj-Mallat
Liam Hamm
Barak Almarzouq
Yong-Xiang Chen
Darrell D. Belke
Latika Singh
Heike Wulff
Andrew P. Braun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545050

1,194 views

Original Research

Published on 24 Feb 2025

Intestinal current measurement detects age-dependent differences in CFTR function in rectal epithelium

in Pharmacology of Ion Channels and Channelopathies

Simon Y. Graeber
Olaf Sommerburg
Yin Yu
Julian Berges
Stephanie Hirtz
Heike Scheuermann
Jasmin Berger
Julia Duerr
Marcus A. Mall

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537095

1,457 views
1 citation

Review

Published on 30 Jan 2025

The enigmatic SLC26A6 multifunctional anion transporter: recent advances in structure-function relationship, pathophysiological significance and novel pharmacological inhibitors

in Pharmacology of Ion Channels and Channelopathies

Ursula E. Seidler

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1536864

1,586 views
1 citation