Original Research

Published on 30 Jan 2023

Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid

Ke Li
Xiu-Hua Yu
Anish R. Maskey
Ibrahim Musa
Zhen-Zheng Wang
Victor Garcia
Austin Guo
Nan Yang
Kamal Srivastava
David Dunkin

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1042756

153 views

Original Research

Published on 25 Jan 2023

Development and optimization of nanoparticles loaded with erucin, a dietary isothiocyanate isolated from Eruca sativa: Antioxidant and antiproliferative activities in ehrlich-ascites carcinoma cell line

Sharabjit Singh
Gurdeep Singh
Shivani Attri
Prabhjot Kaur
Farhana Rashid
Neena Bedi
Shafiul Haque
Essam M. Janahi
Saroj Arora

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1080977

360 views

Systematic Review

Published on 24 Jan 2023

Advanced intestinal regulation improves bowel preparation quality in patients with constipation: A systematic review and network meta-analysis

Liang Ding
JinNan Duan
Tao Yang
ChaoQiong Jin
Jun Luo
Ahuo Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2022.964915

143 views

Original Research

Published on 23 Jan 2023

Elucidating the molecular determinants in the process of gastrin C-terminal pentapeptide amide end activating cholecystokinin 2 receptor by Gaussian accelerated molecular dynamics simulations

Kecheng Yang
Huiyuan Jin
Xu Gao
Gang-Cheng Wang
Guo-Qiang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1054575

223 views

Review

Published on 23 Jan 2023

Current status and future promise of next-generation poly (ADP-Ribose) polymerase 1-selective inhibitor AZD5305

Jingcao Zheng
Zhengyu Li
Wenjiao Min

Frontiers in Pharmacology

doi 10.3389/fphar.2022.979873

253 views

Original Research

Published on 20 Jan 2023

Inhibitory activity of Enhydra fluctuans Lour. on calcium oxalate crystallisation through in silico and in vitro studies

Bornika Chattaraj
Arijit Nandi
Anwesha Das
Amit Sharma
Yadu Nandan Dey
Dharmendra Kumar
Mogana R

Frontiers in Pharmacology

doi 10.3389/fphar.2022.982419

861 views

Original Research

Published on 20 Jan 2023

Nanomolar clodronate induces adenosine accumulation in the perfused rat mesenteric bed and mesentery-derived endothelial cells

M. Verónica Donoso
Felipe Hernández
Rafael Barra
J. Pablo Huidobro-Toro

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1031223

266 views

Mini Review

Published on 20 Jan 2023

Combinational antitumor strategies of exosomes as drug carriers: Mini review

Guixiu Xiao
Zihan Xu
Feng Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1107329

272 views

Original Research

Published on 19 Jan 2023

WXJ-202, a novel Ribociclib derivative, exerts antitumor effects against breast cancer through CDK4/6

Jing Ji
Wenwen Liu
Yuxin Xu
Zhou Xu
Mingxiao Lv
Jing Feng
Jinyu Lv
Xingbei He
Zhen Zhang
Mengru Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1072194

470 views

Original Research

Published on 19 Jan 2023

A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson’s disease

Philip Hartz
Tobias Fehlmann
Gudrun Wagenpfeil
Marcus Michael Unger
Rita Bernhardt

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1094265

570 views

Clinical Trial

Published on 18 Jan 2023

Personalized antiplatelet therapy guided by clopidogrel pharmacogenomics in acute ischemic stroke and transient ischemic attack: A prospective, randomized controlled trial

Xiaoguang Zhang
Shanshan Jiang
Jie Xue
Ying Ding
Jingyu Gu
Liang Hu
Xushen Xu
Zhizhang Li
Yuming Kong
Youmei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.931405

368 views

Correction

Published on 18 Jan 2023

Corrigendum: A novel N-arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage polarization

Mingming Fan
Huijuan Xiao
Dingyun Song
Lili Zhu
Jie Zhang
Xinran Zhang
Jing Wang
Huaping Dai
Chen Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1109002

328 views

Correction

Published on 18 Jan 2023

Addendum: A novel N-Arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage polarization

Mingming Fan
Huijuan Xiao
Dingyun Song
Lili Zhu
Jie Zhang
Xinran Zhang
Jing Wang
Huaping Dai
Chen Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1108989

309 views

Original Research

Published on 18 Jan 2023

Mechanism of crocin I on ANIT-induced intrahepatic cholestasis by combined metabolomics and transcriptomics

Dandan Song
Pei Zhu
Yankai Dong
Mengchao Wang
Anna Zhao
Hongdong Xia
Yunting Chen
Qingguang Zhou
Lun Xiang
Junyi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1088750

371 views

Review

Published on 17 Jan 2023

Perturbed autophagy intervenes systemic lupus erythematosus by active ingredients of traditional Chinese medicine

Rui Tian
Lin Yuan
Yuan Huang
Rui Zhang
Hao Lyu
Shuai Xiao
Dong Guo
Declan William Ali
Marek Michalak
Xing-Zhen Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1053602

447 views

Original Research

Published on 17 Jan 2023

Remdesivir associated sinus bradycardia in patients with COVID-19: A prospective longitudinal study

Maryam Hajimoradi
Babak Sharif Kashani
Farzaneh Dastan
Sina Aghdasi
Atefeh Abedini
Farah Naghashzadeh
Arezoo Mohamadifar
Mohammad Sadegh Keshmiri
Sima Noorali
Somayeh Lookzadeh

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1107198

532 views

Navigation group

Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid

Development and optimization of nanoparticles loaded with erucin, a dietary isothiocyanate isolated from Eruca sativa: Antioxidant and antiproliferative activities in ehrlich-ascites carcinoma cell line

Advanced intestinal regulation improves bowel preparation quality in patients with constipation: A systematic review and network meta-analysis

Elucidating the molecular determinants in the process of gastrin C-terminal pentapeptide amide end activating cholecystokinin 2 receptor by Gaussian accelerated molecular dynamics simulations

Current status and future promise of next-generation poly (ADP-Ribose) polymerase 1-selective inhibitor AZD5305

Inhibitory activity of Enhydra fluctuans Lour. on calcium oxalate crystallisation through in silico and in vitro studies

Nanomolar clodronate induces adenosine accumulation in the perfused rat mesenteric bed and mesentery-derived endothelial cells

Combinational antitumor strategies of exosomes as drug carriers: Mini review

WXJ-202, a novel Ribociclib derivative, exerts antitumor effects against breast cancer through CDK4/6

A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson’s disease

Personalized antiplatelet therapy guided by clopidogrel pharmacogenomics in acute ischemic stroke and transient ischemic attack: A prospective, randomized controlled trial

Corrigendum: A novel N-arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage polarization

Addendum: A novel N-Arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage polarization

Mechanism of crocin I on ANIT-induced intrahepatic cholestasis by combined metabolomics and transcriptomics

Perturbed autophagy intervenes systemic lupus erythematosus by active ingredients of traditional Chinese medicine

Remdesivir associated sinus bradycardia in patients with COVID-19: A prospective longitudinal study