Frontiers in Psychiatry | Behavioral and Psychiatric Genetics

Original Research

Accepted on 19 Jan 2026

Genetic Architecture and Clinical Features of Tourette Syndrome in a child and adolescent cohort: an explorative Clinical Exome-Based Study

in Behavioral and Psychiatric Genetics

Federica Saia
Federica Mirabella
Andrea Longhitano
Nicoletta Maugeri
Rita Barone
Renata Rizzo

Frontiers in Psychiatry

317 views

Original Research

Published on 05 Jan 2026

Association between interleukin-27 and suicidal ideation: a Mendelian randomization analysis and peripheral blood experimental study

in Behavioral and Psychiatric Genetics

Xiwen Hu
Xiaowen Yin
Shengdong Wang
Chunyan Zhu
Xuan Ju
Zhonglin Tan
Lingna Lu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1678780

950 views

Original Research

Accepted on 22 Dec 2025

Editome profiling and cross-cohort validation reveal A-to-I RNA editing dysregulation in the hippocampus and prefrontal cortex of sepsis patients

in Behavioral and Psychiatric Genetics

Jie Shen
Jia-Qi Pan
Tian-Yue Yu
Le-Wen Liu
Yu-Nuo Li
Yun-Yun Jin
Minmin Zhu

Frontiers in Psychiatry

309 views

Review

Published on 29 Oct 2025

The clinical use of epigenetics in psychiatry: a narrative review of epigenetic mechanisms, key candidate genes, and precision psychiatry

in Behavioral and Psychiatric Genetics

Rachel Montel Hayes
Christopher E. Mason
John J. Miller

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1671122

4,960 views

Perspective

Published on 20 Oct 2025

Eating behaviour and eating disorders in individuals with rare neurodevelopmental variants: current knowledge and future research directions

in Behavioral and Psychiatric Genetics

Samuel J. R. A. Chawner

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1627378

1,227 views

Original Research

Published on 08 Oct 2025

Integrative clinical and molecular insights into the comorbidity between depression and sleep apnea syndrome

in Behavioral and Psychiatric Genetics

HaiHua Chen
LanMei Zhuang
ZhiJuan Ji
Xing Sun
Ting Zhu
Bo Wang
Jin Wang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1659330

4,185 views

Methods

Published on 21 Aug 2025

Association analysis between polygenic risk scores and traits: practical guidelines and tutorial with an illustrative data set of schizophrenia

in Behavioral and Psychiatric Genetics

Itziar Irigoien
Patricia Mas-Bermejo
Sergi Papiol
Neus Barrantes-Vidal
Araceli Rosa
Concepción Arenas

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1621972

3,198 views

Original Research

Published on 22 Jul 2025

Molecular insights into the bidirectional link between anxiety and COVID-19: a combined clinical and bioinformatics approach

in Behavioral and Psychiatric Genetics

Wenjie Huang
Biao Hu
Chengyu Gu
Hao Wu
Yize Huang
Dexiang Yang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1643355

3,301 views

Original Research

Published on 11 Jul 2025

A network analysis of gene co-expression in post-mortem brain tissues identifying novel genes and biological pathways underlying major depression

in Behavioral and Psychiatric Genetics

Miaomiao Yan
Man Chen
Qin Jiang
Huilan Huang
Yigao Wu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1556983

3,572 views

Original Research

Published on 04 Mar 2025

Phenotype and psychometric characterization of Phelan-McDermid syndrome patients: pioneering towards personalized medicine

in Behavioral and Psychiatric Genetics

Julián Nevado
Filippo Ciceri
Cristina Bel-Fenellós
Jair A. Tenorio-Castaño
Tamara Maes
Jordi Xaus
Carlos Buesa
Pablo Lapunzina

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1511962

3,346 views
1 citation

Original Research

Published on 24 Feb 2025

Adolescents and adults with FOXP1 syndrome show high rates of anxiety and externalizing behaviors but not psychiatric decompensation or skill loss

in Behavioral and Psychiatric Genetics

Tess Levy
Hailey Silver
Renee Soufer
Audrey Rouhandeh
Alexander Kolevzon
Joseph D. Buxbaum
Paige M. Siper

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1526383

4,156 views
1 citation

Original Research

Published on 20 Dec 2024

Sex and genetic background influence intravenous oxycodone self-administration in the hybrid rat diversity panel

in Behavioral and Psychiatric Genetics

Eamonn P. Duffy
Jonathan O. Ward
Luanne H. Hale
Kyle T. Brown
Andrew J. Kwilasz
Erika A. Mehrhoff
Laura M. Saba
Marissa A. Ehringer
Ryan K. Bachtell

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1505898

2,221 views
2 citations

Brief Research Report

Published on 05 Dec 2024

The effect size of rs521851 in the intron of MAGI2/S-SCAM on HADS-D scores correlates with EAT-26 scores for eating disorders risk

in Behavioral and Psychiatric Genetics

Daria Pinakhina
Evgeny Kasyanov
Grigory Rukavishnikov
Andrey K. Larin
Vladimir A. Veselovsky
Alexander Rakitko
Nikholay Neznanov
Alexander Kibitov
Galina Mazo
Mykyta Artomov

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1416009

2,170 views

Original Research

Published on 03 Oct 2024

A survey in Austria supports the significance of genetic counseling and pharmacogenetic testing for mental illness

in Behavioral and Psychiatric Genetics

Elena Aschauer
Shahriar Izadi Yazdi
Harald Aschauer

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1436875

5,783 views

Original Research

Published on 30 Jul 2024

Major depressive disorder elevates the risk of dentofacial deformity: a bidirectional two-sample Mendelian randomization study

in Behavioral and Psychiatric Genetics

Jinhan Nie
Yi Zhang
Jun Ma
Qing Xue
Min Hu
Huichuan Qi

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1442679

3,265 views
3 citations

Original Research

Published on 29 Jul 2024

Exploring the causal effect of placental physiology in susceptibility to mental and addictive disorders: a Mendelian randomization study

in Behavioral and Psychiatric Genetics

Pablo Jácome-Ferrer
Javier Costas

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1396837

2,790 views
1 citation

Systematic Review

Published on 11 Jul 2024

Efficacy and safety of pharmacogenomic-guided antidepressant prescribing in patients with depression: an umbrella review and updated meta-analysis

in Behavioral and Psychiatric Genetics

Kiflu G. Tesfamicael
Lijun Zhao
Rubén Fernández-Rodríguez
David L. Adelson
Michael Musker
Thomas M. Polasek
Martin David Lewis

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1276410

10,391 views
14 citations

Opinion

Published on 19 Jun 2024

Solving the gender paradox in adolescent suicide: challenges and directions

in Behavioral and Psychiatric Genetics

Aaron Shengting Mai
Yi-Min Wan
Brendan Jen-Wei Tan
Eng-King Tan

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1386153

3,289 views
3 citations

Original Research

Published on 31 May 2024

Causal associations between chronic viral hepatitis and psychiatric disorders: a Mendelian randomization study

in Behavioral and Psychiatric Genetics

Haoshuang Fu
Shaowen Jiang
Shuying Song
Chenxi Zhang
Qing Xie

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1359080

4,118 views
4 citations

Original Research

Published on 17 May 2024

Cross-continental environmental and genome-wide association study on children and adolescent anxiety and depression

in Behavioral and Psychiatric Genetics

Bishal Thapaliya
Bhaskar Ray
Britny Farahdel
Pranav Suresh
Ram Sapkota
Bharath Holla
Jayant Mahadevan
Jiayu Chen
Nilakshi Vaidya
Nora Irma Perrone-Bizzozero

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1384298

8,098 views
11 citations

Original Research

Published on 14 May 2024

The gut microbiota and post-traumatic major depression disorder: insights from bidirectional two-sample Mendelian randomization

in Behavioral and Psychiatric Genetics

Shan Liu
Yu Wang
Yonghu Zhang
Liang Zeng
Lin Ling
Yong Luo
Wenjie Liu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1383664

3,727 views
1 citation

Original Research

Published on 18 Apr 2024

Novel missense variants in brain morphogenic genes associated with depression and schizophrenia

in Behavioral and Psychiatric Genetics

Maxim Karagyaur
Alexandra Primak
Kirill Bozov
Dmitriy Sheleg
Mikhail Arbatsky
Stalik Dzhauari
Maria Illarionova
Ekaterina Semina
Larisa Samokhodskaya
Polina Klimovich

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1338168

5,808 views
8 citations

Brief Research Report

Published on 17 Apr 2024

No gene by stressful life events interaction on individual differences in adults’ self-control

in Behavioral and Psychiatric Genetics

Yayouk Eva Willems
Laurel Raffington
Lannie Ligthart
Rene Pool
Jouke Jan Hottenga
Catrin Finkenauer
Meike Bartels

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1388264

3,010 views
2 citations

Original Research

Published on 15 Apr 2024

Zmiz1 is a novel regulator of brain development associated with autism and intellectual disability

in Behavioral and Psychiatric Genetics

Rajan K. C.
Alina S. Tiemroth
Abbigail N. Thurmon
Stryder M. Meadows
Maria J. Galazo

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1375492

5,903 views
9 citations

120 articles

articles

Genetic Architecture and Clinical Features of Tourette Syndrome in a child and adolescent cohort: an explorative Clinical Exome-Based Study

Association between interleukin-27 and suicidal ideation: a Mendelian randomization analysis and peripheral blood experimental study

Editome profiling and cross-cohort validation reveal A-to-I RNA editing dysregulation in the hippocampus and prefrontal cortex of sepsis patients

The clinical use of epigenetics in psychiatry: a narrative review of epigenetic mechanisms, key candidate genes, and precision psychiatry

Eating behaviour and eating disorders in individuals with rare neurodevelopmental variants: current knowledge and future research directions

Integrative clinical and molecular insights into the comorbidity between depression and sleep apnea syndrome

Association analysis between polygenic risk scores and traits: practical guidelines and tutorial with an illustrative data set of schizophrenia

Molecular insights into the bidirectional link between anxiety and COVID-19: a combined clinical and bioinformatics approach

A network analysis of gene co-expression in post-mortem brain tissues identifying novel genes and biological pathways underlying major depression

Phenotype and psychometric characterization of Phelan-McDermid syndrome patients: pioneering towards personalized medicine

Adolescents and adults with FOXP1 syndrome show high rates of anxiety and externalizing behaviors but not psychiatric decompensation or skill loss

Sex and genetic background influence intravenous oxycodone self-administration in the hybrid rat diversity panel

The effect size of rs521851 in the intron of MAGI2/S-SCAM on HADS-D scores correlates with EAT-26 scores for eating disorders risk

A survey in Austria supports the significance of genetic counseling and pharmacogenetic testing for mental illness

Major depressive disorder elevates the risk of dentofacial deformity: a bidirectional two-sample Mendelian randomization study

Exploring the causal effect of placental physiology in susceptibility to mental and addictive disorders: a Mendelian randomization study

Efficacy and safety of pharmacogenomic-guided antidepressant prescribing in patients with depression: an umbrella review and updated meta-analysis

Solving the gender paradox in adolescent suicide: challenges and directions

Causal associations between chronic viral hepatitis and psychiatric disorders: a Mendelian randomization study

Cross-continental environmental and genome-wide association study on children and adolescent anxiety and depression

The gut microbiota and post-traumatic major depression disorder: insights from bidirectional two-sample Mendelian randomization

Novel missense variants in brain morphogenic genes associated with depression and schizophrenia

No gene by stressful life events interaction on individual differences in adults’ self-control

Zmiz1 is a novel regulator of brain development associated with autism and intellectual disability