ORIGINAL RESEARCH article
Front. Public Health
Sec. Environmental Health and Exposome
Mortality risk effects of ozone and meteorological factors: a 10-year time-series study
Na Cao 1
Xiaojuan Yang 2
Yifei Chen 1
Lifang Zhao 1
Shuai Guo 1
Rui Li 1
Zhu Guiming 1
Lin Ma 2
Zhihong Zhang 1
1. Shanxi Medical University School of Public Health, Taiyuan, China
2. Shanxi Provincial Center for Disease Control and Prevention, Taiyuan, China
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Abstract
Background: Tropospheric ozone (O₃) is increasingly becoming the dominant urban air pollutant in China, posing significant public health risks that are exacerbated by meteorological conditions. A clear understanding of how O₃-related health effects are modified by atmospheric factors is crucial for targeted risk mitigation. Methods: This ten-year time-series study (2013-2022) was conducted in Taiyuan, China. We analyzed data on daily O₃ concentrations, meteorological factors, and all-cause and cause-specific mortality. The analysis employed Generalized Additive Models (GAMs) to assess the lagged effects of O₃ exposure on mortality and to investigate the interactions between O₃ and key atmospheric determinants, including temperature, sunshine duration, and season. Results: The study revealed distinct patterns of O₃-related mortality risk modified by meteorological conditions. The 10-year average daily O₃ concentration was 92.92 μg/m³. O₃ exposure significantly contributed to all-cause, respiratory, and circulatory mortality with lagged effects. While atmospheric pressure, sunshine duration, temperature, and season all influenced the O₃-mortality relationship, the effect was primarily modified through significant interactions with sunshine duration, season, and temperature. These interactive health risks were more pronounced among females and the elderly. Conclusions: Our study provides strong evidence that O3 increases the risk of all-cause, respiratory and circulatory mortality in the population. In addition, there were interactions between meteorological factors and O3, primarily involving sunshine duration, season and temperature.
Summary
Keywords
Generalized additive model, health risk assessment, Interaction, Meteorological factors, Mortality, Ozone
Received
09 November 2025
Accepted
31 January 2026
Copyright
© 2026 Cao, Yang, Chen, Zhao, Guo, Li, Guiming, Ma and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Zhihong Zhang
Disclaimer
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