Frontiers in Toxicology

Original Research

Published on 14 Dec 2021

An Adverse Outcome Pathway for Decreased Lung Function Focusing on Mechanisms of Impaired Mucociliary Clearance Following Inhalation Exposure

in In Vitro Toxicology

Karsta Luettich
Monita Sharma
Hasmik Yepiskoposyan
Damien Breheny
Frazer J. Lowe

Frontiers in Toxicology

doi 10.3389/ftox.2021.750254

7,072 views
18 citations

Review

Published on 14 Dec 2021

The Future of Neurotoxicology: A Neuroelectrophysiological Viewpoint

in Neurotoxicology

David W. Herr

Frontiers in Toxicology

doi 10.3389/ftox.2021.729788

5,203 views

Mini Review

Published on 13 Dec 2021

Radiolabeling of Nanomaterials: Advantages and Challenges

in Nanotoxicology

Wanqin Dai
Junzhe Zhang
Yun Wang
Chunlei Jiao
Zhuda Song
Yuhui Ma
Yayun Ding
Zhiyong Zhang
Xiao He

Frontiers in Toxicology

doi 10.3389/ftox.2021.753316

7,140 views
22 citations

Original Research

Published on 13 Dec 2021

Development and Application of Nanoparticle-Nanopolymer Composite Spheres for the Study of Environmental Processes

in Nanotoxicology

Robert J. Rauschendorfer
Kyle M. Whitham
Star Summer
Samantha A. Patrick
Aliandra E. Pierce
Haley Sefi-Cyr
Soheyl Tadjiki
Michael D. Kraft
Steven R. Emory
David A. Rider

Frontiers in Toxicology

doi 10.3389/ftox.2021.752296

6,446 views
14 citations

Methods

Published on 06 Dec 2021

A Low-Serum Culture System for Prolonged in Vitro Toxicology Experiments on a Macrophage System

in Immunotoxicology

Bastien Dalzon
Anaelle Torres
Julie Devcic
Daphna Fenel
Jacques-Aurélien Sergent
Thierry Rabilloud

Frontiers in Toxicology

doi 10.3389/ftox.2021.780778

6,722 views
21 citations

Original Research

Published on 30 Nov 2021

Using Live Imaging and FUCCI Embryonic Stem Cells to Rank DevTox Risks: Adverse Growth Effects of PFOA Compared With DEP Are 26 Times Faster, 1,000 Times More Sensitive, and 13 Times Greater in Magnitude

in Regulatory Toxicology

Mohammed Abdulhasan
Ximena Ruden
Yuan You
Sean M. Harris
Douglas M. Ruden
Awoniyi O. Awonuga
Ayesha Alvero
Elizabeth E. Puscheck
Daniel A. Rappolee

Frontiers in Toxicology

doi 10.3389/ftox.2021.709747

6,765 views
5 citations

Review

Published on 22 Nov 2021

A Review of Per- and Polyfluorinated Alkyl Substance Impairment of Reproduction

in Developmental and Reproductive Toxicology

Weston S. Chambers
Jaida G. Hopkins
Sean M. Richards

Frontiers in Toxicology

doi 10.3389/ftox.2021.732436

24,714 views
136 citations

Original Research

Published on 11 Nov 2021

Paraquat Toxicogenetics: Strain-Related Reduction of Tyrosine Hydroxylase Staining in Substantia Nigra in Mice

in Predictive Toxicology and Exposomics

Carolina Torres-Rojas
Wenyuan Zhao
Daming Zhuang
James P. O’Callaghan
Lu Lu
Megan K. Mulligan
Robert W. Williams
Byron C. Jones

Frontiers in Toxicology

doi 10.3389/ftox.2021.722518

3,305 views

Review

Published on 10 Nov 2021

Harnessing the Biology of Canine Intestinal Organoids to Heighten Understanding of Inflammatory Bowel Disease Pathogenesis and Accelerate Drug Discovery: A One Health Approach

in Predictive Toxicology and Exposomics

Jamie J. Kopper
Chelsea Iennarella-Servantez
Albert E. Jergens
Dipak K. Sahoo
Emilie Guillot
Agnes Bourgois-Mochel
Marilyn N. Martinez
Karin Allenspach
Jonathan P. Mochel

Frontiers in Toxicology

doi 10.3389/ftox.2021.773953

12,660 views
41 citations

Perspective

Published on 04 Nov 2021

Canadian Regulatory Perspective on Next Generation Risk Assessments for Pest Control Products and Industrial Chemicals

in In Vitro Toxicology

Yadvinder Bhuller
Deborah Ramsingh
Marc Beal
Sunil Kulkarni
Matthew Gagne
Tara S Barton-Maclaren

Frontiers in Toxicology

doi 10.3389/ftox.2021.748406

11,632 views
31 citations

Review

Published on 04 Nov 2021

Centrality of Myeloid-Lineage Phagocytes in Particle-Triggered Inflammation and Autoimmunity

in Immunotoxicology

Olivia K. Favor
James J. Pestka
Melissa A. Bates
Kin Sing Stephen Lee

Frontiers in Toxicology

doi 10.3389/ftox.2021.777768

8,598 views
10 citations

Original Research

Published on 29 Oct 2021

Bridging Sex-Specific Differences in the CAR-Mediated Hepatocarcinogenesis of Nitrapyrin Using Molecular and Apical Endpoints

in Regulatory Toxicology

Lynea Murphy
Matthew J. LeBaron
Kamin Johnson
Reza J. Rasoulpour
Xiujuan Wang
Jessica LaRocca

Frontiers in Toxicology

doi 10.3389/ftox.2021.766196

2,176 views
3 citations

Review

Published on 27 Oct 2021

On the Use and Interpretation of Areola/Nipple Retention as a Biomarker for Anti-androgenic Effects in Rat Toxicity Studies

in Developmental and Reproductive Toxicology

Camilla Lindgren Schwartz
Sofie Christiansen
Ulla Hass
Louise Ramhøj
Marta Axelstad
Nathalie Michelle Löbl
Terje Svingen

Frontiers in Toxicology

doi 10.3389/ftox.2021.730752

9,761 views
21 citations

Methods

Published on 15 Oct 2021

Development of the SciRAP Approach for Evaluating the Reliability and Relevance of in vitro Toxicity Data

in Regulatory Toxicology

Nicolas Roth
Johanna Zilliacus
Anna Beronius

Frontiers in Toxicology

doi 10.3389/ftox.2021.746430

10,769 views
51 citations

Original Research

Published on 08 Oct 2021

Effects of Prenatal Exposure to Titanium Dioxide Nanoparticles on DNA Methylation and Gene Expression Profile in the Mouse Brain

in Developmental and Reproductive Toxicology

Ken Tachibana
Shotaro Kawazoe
Atsuto Onoda
Masakazu Umezawa
Ken Takeda

Frontiers in Toxicology

doi 10.3389/ftox.2021.705910

6,085 views
15 citations

Original Research

Published on 06 Oct 2021

Development of Microfluidic, Serum-Free Bronchial Epithelial Cells-on-a-Chip to Facilitate a More Realistic In vitro Testing of Nanoplastics

in Nanotoxicology

Govind Gupta
Srikanth Vallabani
Romain Bordes
Kunal Bhattacharya
Bengt Fadeel

Frontiers in Toxicology

doi 10.3389/ftox.2021.735331

6,574 views
18 citations

Original Research

Published on 01 Oct 2021

Influence of Aging on Bioaccumulation and Toxicity of Copper Oxide Nanoparticles and Dissolved Copper in the Sediment-Dwelling Oligochaete Tubifex tubifex: A Long-Term Study Using a Stable Copper Isotope

in Nanotoxicology

Amalie Thit
Monica Hamann Sandgaard
Joachim Sturve
Catherine Mouneyrac
Anders Baun
Henriette Selck

Frontiers in Toxicology

doi 10.3389/ftox.2021.737158

2,837 views
10 citations

Systematic Review

Published on 29 Sep 2021

Current Insights into Potential Effects of Micro-Nanoplastics on Human Health by in-vitro Tests

in Nanotoxicology

Marta Llorca
Marinella Farré

Frontiers in Toxicology

doi 10.3389/ftox.2021.752140

15,396 views
67 citations

Original Research

Published on 29 Sep 2021

Seasonally Related Disruption of Metabolism by Environmental Contaminants in Male Goldfish (Carassius auratus)

in Developmental and Reproductive Toxicology

Lisa N. Bottalico
Julia Korlyakova
Aalim M. Weljie
Hamid R Habibi

Frontiers in Toxicology

doi 10.3389/ftox.2021.750870

3,155 views
6 citations

Review

Published on 13 Sep 2021

Potential of NRF2 Pathway in Preventing Developmental and Reproductive Toxicity of Fine Particles

in Developmental and Reproductive Toxicology

Ying-Ji Li
Ken Takeda
Masayuki Yamamoto
Tomoyuki Kawada

Frontiers in Toxicology

doi 10.3389/ftox.2021.710225

3,680 views
3 citations

Brief Research Report

Published on 27 Aug 2021

Reports of Doses Administered and Adverse Reactions to Snake Antivenom Used in Uruguay in 2018

in Immunotoxicology

Alba Negrin
María Alejandra Battocletti
Carolina Juanena
Victor Morais

Frontiers in Toxicology

doi 10.3389/ftox.2021.690964

4,484 views
4 citations

Original Research

Published on 11 Aug 2021

Effect of Carbon Black Nanoparticle on Neonatal Lymphoid Tissues Depending on the Gestational Period of Exposure in Mice

in Developmental and Reproductive Toxicology

Atsuto Onoda
Saki Okamoto
Ryuhei Shimizu
Yasser S. El-Sayed
Shiho Watanabe
Shuhei Ogawa
Ryo Abe
Masao Kamimura
Kohei Soga
Ken Tachibana

Frontiers in Toxicology

doi 10.3389/ftox.2021.700392

3,418 views
2 citations

Brief Research Report

Published on 19 Jul 2021

Analysis of Fluoride Contamination in Sheep Serum and in Water in the North East of Tunisia Ore Deposits

in Regulatory Toxicology

Rim Hadiji
Iheb Bannouri
Saida Zelfani
Aymen Mamlouk
Hela Jaballah
Arij Jemmal
Nadia Sdouga
Samir Ben Youssef

Frontiers in Toxicology

doi 10.3389/ftox.2021.643664

3,341 views
2 citations

Mini Review

Published on 19 Jul 2021

Insect in vitro System for Toxicology Studies — Current and Future Perspectives

in In Vitro Toxicology

Sheeja Cc
Damodaran Arun
Lekha Divya

Frontiers in Toxicology

doi 10.3389/ftox.2021.671600

5,000 views
5 citations