Frontiers in Toxicology

Original Research

Accepted on 11 Aug 2025

Occupational exposure and its mechanistic link to allergic asthma and lung function decline; a data-driven approach coupled to mining of adverse outcome pathway signatures

in Occupational Toxicology

Rob Stierum
Manosij Ghosh
Marjolein Meijerink
Xavier Pinho
Vivi Schlunssen
Anjoeka Pronk
Jolanda Van Bilsen

Frontiers in Toxicology

doi 10.3389/ftox.2025.1589380

Perspective

Published on 11 Aug 2025

Uncovering exposome-related diseases through the pathologic metallome: a novel approach for clinical populations

in Occupational Toxicology

Riccardo Leinardi
François Huaux

Frontiers in Toxicology

doi 10.3389/ftox.2025.1625874

322 views

Original Research

Published on 11 Aug 2025

Assessment of heated herbal products’ tobacco harm reduction potential: pre‐clinical and clinical studies

in Regulatory Toxicology

Alvaro-Flavio Marinas-Lacasta
Ian M. Fearon
Matthew Stevenson
Tasnim Abusalem
Fiona Chapman
Edgar Trelles Sticken
Roman Wieczorek
Sarah Jean Pour
Ole Dethloff
Ourania Komini

Frontiers in Toxicology

doi 10.3389/ftox.2025.1589480

1,049 views

Original Research

Accepted on 08 Aug 2025

Reproduction of the Human Relevant Potency Threshold (HRPT) for Estrogen Receptor Alpha Agonism in an Inference Performance Screen for ICCVAM's Regulatory Scientific Confidence Framework

in Regulatory Toxicology

Jessica Ryman Ph.D., D.A.B.T.
Richard Becker

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657708

454 views

Review

Published on 08 Aug 2025

Fetal bovine serum: how to leave it behind in the pursuit of more reliable science

in In Vitro Toxicology

Tilo Weber
Atena Malakpour-Permlid
Aline Chary
Vito D’Alessandro
Leah Haut
Sebastian Seufert
Esther Veronika Wenzel
James Hickman
Karen Bieback
Joachim Wiest

Frontiers in Toxicology

doi 10.3389/ftox.2025.1612903

1,781 views

Original Research

Accepted on 07 Aug 2025

Error-Corrected Next Generation Sequencing Mutagenicity Assays in Human HepaRG™ Cells as Human-Relevant Genetic Toxicology New Approach Methodology

in Regulatory Toxicology

A. Rasim Barutcu
Nimisha Bhattarai
Raymond Samuel
Jamie Scaglione
Leslie Recio

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657189

221 views

Original Research

Published on 06 Aug 2025

Epidemiological investigation of venomous snakebites in Yunnan Province

in Clinical Toxicology

Qinfen Gao
Yajun Teng
Chao Xiao
Rui Zeng
Bin Han
Hong Gao
Jianhai Wang
Xiaoyan Li
Canju Yang
Jianneng Dai

Frontiers in Toxicology

doi 10.3389/ftox.2025.1609487

710 views

Hypothesis and Theory

Accepted on 05 Aug 2025

Determining a NOAEL for the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA) Core Study

in Developmental and Reproductive Toxicology

Melissa Badding
Noor Aly
Kevin Sondenheimer

Frontiers in Toxicology

doi 10.3389/ftox.2025.1639737

136 views

Case Report

Accepted on 04 Aug 2025

Mercury exposure leading to functional vitamin B12 deficiency and subacute combined degeneration, a case report and literature review

in Occupational Toxicology

Isidora Semnic
Valentino Racki
Vladimira Vuletić

Frontiers in Toxicology

doi 10.3389/ftox.2025.1580275

183 views

Original Research

Accepted on 04 Aug 2025

Exploring Plasticisers-Osteoporosis Links and Mechanisms: A Cohort and Network Toxicology Study

in Environmental Toxicology

Xingyao Yang
Xin Wang
Shifu Bao
Zhengjiang Li
Shuxing Xing
Zhangzhen Du

Frontiers in Toxicology

doi 10.3389/ftox.2025.1617663

Original Research

Published on 04 Aug 2025

Refinement of a workflow for human relevance assessment of adverse outcome pathways and associated new approach methodologies

in Regulatory Toxicology

Annick D. van den Brand
Julia J. Meerman
Christina H. J. Veltman
Mirjam Luijten

Frontiers in Toxicology

doi 10.3389/ftox.2025.1616817

649 views

Case Report

Published on 31 Jul 2025

Case Report: Successful management of severe suicidal lamotrigine overdose-induced status epilepticus with sustained low-efficiency dialysis

in Clinical Toxicology

Naoki Kawahara
Hiroki Matsui
Koji Morishita

Frontiers in Toxicology

doi 10.3389/ftox.2025.1622752

597 views

Original Research

Accepted on 30 Jul 2025

Integral approach to organelle profiling in human iPSCderived cardiomyocytes enhances in-vitro cardiac safety classification of known cardiotoxic compounds

in In Vitro Toxicology

Brigitta Rita Szabo
Jeroen Stein
Anna Savchenko
Thomas Hutschalik
Filip Van Nieuwerburgh
Tim Meese
Georgios Kosmidis
Paul G A Volders
Elena Matsa

Frontiers in Toxicology

doi 10.3389/ftox.2025.1644119

156 views

Original Research

Published on 30 Jul 2025

Research on the impact of graphene oxide in feed on growth and health parameters in calves

in Food and Nutritional Toxicology

Tereza Aulichova
Sylvie Skalickova
Kopec Tomas
Pompido Chilala
Pavel Horky

Frontiers in Toxicology

doi 10.3389/ftox.2025.1560078

606 views

Systematic Review

Accepted on 25 Jul 2025

Stroke Risk Following Bee and Wasp Stings: A Systematic Review of Ischemic and Hemorrhagic Events

in Clinical Toxicology

Jorge Vasconez-Gonzalez
Juan Sebastian Izquierdo-Condoy
Karen Delgado-Moreira
Maria de Lourdes Noboa Lasso
Esteban Gamez-Rivera
Camila Salazar
María Belén Lopez-Molina
Esteban Ortiz-Prado

Frontiers in Toxicology

doi 10.3389/ftox.2025.1632308

285 views

Original Research

Accepted on 25 Jul 2025

New Insights into Ornidazole-Induced Male Reproductive Toxicity in Rats via Energy Metabolism Disruption

in Developmental and Reproductive Toxicology

Qiujian Feng
Zhuozhi Gong
Xuefan Jiang
Xiaojing An
Bin Yan
Elena Colonnello
Fu Wang
Jun Guo
Shengjing Liu

Frontiers in Toxicology

doi 10.3389/ftox.2025.1652955

164 views