Frontiers in Toxicology

Original Research

Accepted on 29 Jan 2026

Effect of the cysteine prodrug L-2-oxothiazolidine-4-carboxylic acid on in vivo platelet activation, oxidative stress, and procoagulant responses induced by waterpipe smoke exposure in mice

in In Vitro Toxicology

Sumaya Beegam
Nur Elena Zaaba
Ozaz Elzaki
Javed Yasin
Badreldin H. Ali
Abderrahim Nemmar

Frontiers in Toxicology

Perspective

Published on 29 Jan 2026

Addressing animal methods bias through government-led initiatives

in In Vitro Toxicology

Jessica S. Kopew
Merel Ritskes-Hoitinga
Mikalah Singer
Emily R. Trunnell
Gabby Vidaurre
Catharine E. Krebs

Frontiers in Toxicology

doi 10.3389/ftox.2026.1761759

344 views

Original Research

Accepted on 27 Jan 2026

A Comparison of Honeybee and Scorpion Venoms as Anticancer Agents Against three different cancer cell lines: Lung, Colon, and Breast Cancer

in Clinical Toxicology

Fatma Galal
Fahad M Alshammari
Abdulrahman S. Aldaghmi
Elsayed E. Hafez
Ghada El-sayed
Riyadh H Aeban
Saad A Alharb

Frontiers in Toxicology

Original Research

Accepted on 27 Jan 2026

Appearance-Based Computer Vision Pipeline for Multi-Animal Monitoring of Canine Activity, Behavior and Clinical Observations

in Computational Toxicology and Informatics

Eline Eberhardt
Jef Plochaet
Tanguy Ophoff
Floris De Feyter
Sarah De Landtsheer
Greet B.A. Teuns
Maarten Vergauwen
Bianca Feyen
Toon Goedemé
Ivan Kopljar

Frontiers in Toxicology

Review

Accepted on 26 Jan 2026

Impact of PFAS exposure on lipid metabolic pathways: Mechanisms and implications in carcinogenesis

in Clinical Toxicology

Emily J. Ferguson
Josiane Weber Tessmann
Yekaterina Y Zaytseva

Frontiers in Toxicology

102 views

Review

Accepted on 26 Jan 2026

Predicted No Effect Concentrations (PNECs) of antifungals for wastewater management and agricultural use

in Environmental Toxicology

D. Gil
S. José
A. Ascenso
Monika Novak Babič
Esther Segal
Joseph Meletiadis
J. P. Gangneux
C. J. Weiskerger
Helena Solo-Gabriele
Elisabete Valério

Frontiers in Toxicology

Original Research

Accepted on 22 Jan 2026

Use of Gastroscopy in the Management of Pediatric Toxic Ingestions: Insights from a Decade of Experience – A Retrospective Study

in Clinical Toxicology

Marco Marano
Lavinia Di Meglio
Mara Pisani
Bianca Maria Goffredo
Carla Olita
Simona Faraci
Francesca Rea
Salvatore Perdichizzi
Giorgio Zampini
Piero David

Frontiers in Toxicology

Original Research

Published on 22 Jan 2026

Nicotine-free electronic vape fluid stimulates angiogenic processes in vitro through ARF6-mediated oxidative stress

in In Vitro Toxicology

Lewis Spurrier-Best
David Butcher
Evangelene Blackham-Hayward
Zsuzsanna Kertesz
Havovi Chichger

Frontiers in Toxicology

doi 10.3389/ftox.2025.1699112

807 views

Perspective

Accepted on 21 Jan 2026

Foreign Body Reaction: Towards a macrophage-centered Adverse Outcome Pathway for fibrotic encapsulation

in In Vitro Toxicology

Tom Meseberg
Susanne Kurz
Juliane Spohn

Frontiers in Toxicology

Original Research

Accepted on 20 Jan 2026

Multi-Task Deep Learning Models for Mechanism-Based Prediction of Developmental and Reproductive Toxicity (DART) using ToxCast Bioassays

in In Vitro Toxicology

Siyeol Ahn
Hojun Jun
Jinwon Hwang
Donghyeon Kim
Hyunjun Kim
Wooseok Kim
Yunjung Lee
Changwon Lim
Jinhee Choi

Frontiers in Toxicology

201 views

Mini Review

Accepted on 19 Jan 2026

From Prioritization to Implementation: Updating the PARC WP5 Project Portfolio Through the Second Prioritization Round

in Developmental and Reproductive Toxicology

Celia Garcia Arenas
Kiara Aiello
Terje Svingen
Dries Knapen
Saadia Kerdine-Römer
Birgitte Lindeman
Nicola Margareta Smith
Ludovic Le Hegarat
Tamara Vanhaecke
Gilles Riviere

Frontiers in Toxicology

128 views

Original Research

Accepted on 19 Jan 2026

Role of the protease-activated receptor 2 in multi-walled carbon nanotube-induced macrophage polarization ex vivo and airway fibrosis in murine allergic lung disease in vivo

in Nanotoxicology

Logan Tisch
Ryan D. Bartone
Silvio Antoniak
James C. Bonner

Frontiers in Toxicology

Brief Research Report

Accepted on 19 Jan 2026

A case report of arsenic-induced peripheral neuropathy misdiagnosed as Guillain-Barré syndrome

in Clinical Toxicology

Shanshan Fu
Guanao Wu
Yibo Zhan
Hui Xia
Chang Zhou
Jingjing Zeng
Ye Tang
Boyan Pan
Zequan Zheng
Min Zhao

Frontiers in Toxicology

109 views

Original Research

Published on 16 Jan 2026

The lack of efficacy of tirzepatide in mitigating cisplatin-induced neurotoxicity and cognitive impairment in rats

in Neurotoxicology

Hanan Mubarak Almutairi
Ahmad Hamad Alhowail

Frontiers in Toxicology

doi 10.3389/ftox.2026.1752511

538 views

Mini Review

Accepted on 15 Jan 2026

Microplastic Toxicity: Mechanisms, Assessment Methods, and Future Research Directions

in Nanotoxicology

Yifan Zhang
Jiale Ren
Binying Zheng
Jiefang Sun
Jing Zhang
Yumin Niu
Bing Shao
Yushen Jin

Frontiers in Toxicology

207 views

Perspective

Published on 15 Jan 2026

Risk assessment of metals measured in regulated Canadian dried cannabis and cannabis vaping products: case study and perspectives

in Regulatory Toxicology

Sathish Achuthan
Andrew Waye
Hanan Abramovici

Frontiers in Toxicology

doi 10.3389/ftox.2025.1755875

997 views

Original Research

Published on 15 Jan 2026

Testicular mitochondrial redox imbalance and impaired oxidative phosphorylation underlie microplastic-induced testicular dysfunction in Wistar rats

in Developmental and Reproductive Toxicology

Samuel Abiodun Kehinde
Tolulope Peter Fatokun
Sarva Mangala Praveena
Abosede Temitope Olajide
Chau Ling Tham
Mariana Teles Pereira
Sasitorn Chusri

Frontiers in Toxicology

doi 10.3389/ftox.2026.1699288

577 views

Perspective

Published on 15 Jan 2026

A user-informed perspective of the toxicological data gap in India’s cannabis landscape

in Regulatory Toxicology

Muzafar Riyaz

Frontiers in Toxicology

doi 10.3389/ftox.2025.1734313

440 views

Original Research

Accepted on 13 Jan 2026

Clinical features of toxic encephalopathy induced by 1,2-Dichloroethane

in Clinical Toxicology

Yuquan Chen
Jiaqi Chen
Yifan Ye
Yuqiang Lin
Zhiqian Yang
Zhi Wang

Frontiers in Toxicology

113 views

Mini Review

Published on 12 Jan 2026

Bridging science and curriculum: preparing future leaders in computational toxicology

in Computational Toxicology and Informatics

Frances Hall
Candice Johnson

Frontiers in Toxicology

doi 10.3389/ftox.2025.1662963

630 views

Review

Published on 12 Jan 2026

The zebrafish in toxicology: a bibliometric analysis reveals current trends and future avenues for predictive safety assessment

in Developmental and Reproductive Toxicology

Carla Lima
Darlan Gusso
Geonildo Rodrigo Disner
Felipe Justiniano Pinto
Maria Alice Pimentel Falcão
João Gabriel Santos Rosa
Mônica Lopes-Ferreira

Frontiers in Toxicology

doi 10.3389/ftox.2025.1700031

867 views

Original Research

Published on 12 Jan 2026

Role of bisphenol A in the aberrant activation of ionotropic glutamate transporters in the cerebral cortex and altered behavioral responses in C57BL/6J mice

in Neurotoxicology

Jasim Khan
Mohammad Waseem
Kajal Kamble
Suhel Parvez
Basu Dev Banerjee
Sarika Gupta
Sheikh Raisuddin

Frontiers in Toxicology

doi 10.3389/ftox.2025.1680589

589 views

Review

Published on 12 Jan 2026

Food contaminants: mechanisms of toxicity, computational assessment, and mitigation

in Computational Toxicology and Informatics

Laura Escorihuela
Rajesh Kumar Pathak
Benjamí Martorell
Vikas Kumar

Frontiers in Toxicology

doi 10.3389/ftox.2025.1719447

1,074 views

Mini Review

Published on 09 Jan 2026

Beyond the amyloid hypothesis: leveraging human-centered complex in vitro models to decode Alzheimer’s disease etiology

in In Vitro Toxicology

Matthew Price
Francesca Pistollato

Frontiers in Toxicology

doi 10.3389/ftox.2025.1753572

1,695 views

634 articles

articles

Effect of the cysteine prodrug L-2-oxothiazolidine-4-carboxylic acid on in vivo platelet activation, oxidative stress, and procoagulant responses induced by waterpipe smoke exposure in mice

Addressing animal methods bias through government-led initiatives

A Comparison of Honeybee and Scorpion Venoms as Anticancer Agents Against three different cancer cell lines: Lung, Colon, and Breast Cancer

Appearance-Based Computer Vision Pipeline for Multi-Animal Monitoring of Canine Activity, Behavior and Clinical Observations

Impact of PFAS exposure on lipid metabolic pathways: Mechanisms and implications in carcinogenesis

Predicted No Effect Concentrations (PNECs) of antifungals for wastewater management and agricultural use

Use of Gastroscopy in the Management of Pediatric Toxic Ingestions: Insights from a Decade of Experience – A Retrospective Study

Nicotine-free electronic vape fluid stimulates angiogenic processes in vitro through ARF6-mediated oxidative stress

Foreign Body Reaction: Towards a macrophage-centered Adverse Outcome Pathway for fibrotic encapsulation

Multi-Task Deep Learning Models for Mechanism-Based Prediction of Developmental and Reproductive Toxicity (DART) using ToxCast Bioassays

From Prioritization to Implementation: Updating the PARC WP5 Project Portfolio Through the Second Prioritization Round

Role of the protease-activated receptor 2 in multi-walled carbon nanotube-induced macrophage polarization ex vivo and airway fibrosis in murine allergic lung disease in vivo

A case report of arsenic-induced peripheral neuropathy misdiagnosed as Guillain-Barré syndrome

The lack of efficacy of tirzepatide in mitigating cisplatin-induced neurotoxicity and cognitive impairment in rats

Microplastic Toxicity: Mechanisms, Assessment Methods, and Future Research Directions

Risk assessment of metals measured in regulated Canadian dried cannabis and cannabis vaping products: case study and perspectives

Testicular mitochondrial redox imbalance and impaired oxidative phosphorylation underlie microplastic-induced testicular dysfunction in Wistar rats

A user-informed perspective of the toxicological data gap in India’s cannabis landscape

Clinical features of toxic encephalopathy induced by 1,2-Dichloroethane

Bridging science and curriculum: preparing future leaders in computational toxicology

The zebrafish in toxicology: a bibliometric analysis reveals current trends and future avenues for predictive safety assessment

Role of bisphenol A in the aberrant activation of ionotropic glutamate transporters in the cerebral cortex and altered behavioral responses in C57BL/6J mice

Food contaminants: mechanisms of toxicity, computational assessment, and mitigation

Beyond the amyloid hypothesis: leveraging human-centered complex in vitro models to decode Alzheimer’s disease etiology