Frontiers in Toxicology

Original Research

Published on 10 May 2024

The application of natural language processing for the extraction of mechanistic information in toxicology

in Computational Toxicology and Informatics

Marie Corradi
Thomas Luechtefeld
Alyanne M. de Haan
Raymond Pieters
Jonathan H. Freedman
Tamara Vanhaecke
Mathieu Vinken
Marc Teunis

Frontiers in Toxicology

doi 10.3389/ftox.2024.1393662

10,365 views
3 citations

Case Report

Published on 09 May 2024

Asystole in a young child with tetrahydrocannabinol overdose: a case report and review of literature

in Clinical Toxicology

Mats Steffi Jennifer Masilamani
Rebecca Leff
Yu Kawai

Frontiers in Toxicology

doi 10.3389/ftox.2024.1371651

1,585 views

Review

Published on 07 May 2024

Impact of dioxins on reproductive health in female mammals

in Developmental and Reproductive Toxicology

Nour Aldeli
Denis Murphy
Abdulsamie Hanano

Frontiers in Toxicology

doi 10.3389/ftox.2024.1392257

3,002 views
7 citations

Editorial

Published on 30 Apr 2024

Editorial: Neglected tropical diseases: tackling the challenges of a global world

in Immunotoxicology

Armanda Rodrigues
Gabriela Santos-Gomes

Frontiers in Toxicology

doi 10.3389/ftox.2024.1417438

1,283 views

Original Research

Published on 30 Apr 2024

Acute intoxication with diisopropylfluorophosphate promotes cellular senescence in the adult male rat brain

in Neurotoxicology

Yi-Hua Tsai
Eduardo A. González
Ana C. G. Grodzki
Donald A. Bruun
Naomi H. Saito
Danielle J. Harvey
Pamela J. Lein

Frontiers in Toxicology

doi 10.3389/ftox.2024.1360359

1,664 views
1 citation

Perspective

Published on 26 Apr 2024

New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project

in Neurotoxicology

Tamara Tal
Oddvar Myhre
Ellen Fritsche
Joëlle Rüegg
Kai Craenen
Kiara Aiello-Holden
Caroline Agrillo
Patrick J. Babin
Beate I. Escher
Hubert Dirven

Frontiers in Toxicology

doi 10.3389/ftox.2024.1359507

5,390 views
18 citations

Original Research

Published on 26 Apr 2024

Impact of a varied set of stimuli on a suite of immunological parameters within peripheral blood mononuclear cells: toward a non-animal approach for assessing immune modulation by materials intended for human use

in Immunotoxicology

Stella Cochrane
Ramya Rajagopal
David Sheffield
Fay Stewart
Lindsay Hathaway
Nicholas M. Barnes
Omar Qureshi
John Gordon

Frontiers in Toxicology

doi 10.3389/ftox.2024.1335110

1,843 views
1 citation

Review

Published on 22 Apr 2024

Abusive use of anabolic androgenic steroids, male sexual dysfunction and infertility: an updated review

in Developmental and Reproductive Toxicology

Rafael de Almeida Azevedo
Bruno Gualano
Thiago Afonso Teixeira
Bruno C. G. Nascimento
Jorge Hallak

Frontiers in Toxicology

doi 10.3389/ftox.2024.1379272

5,339 views
5 citations

Original Research

Published on 19 Apr 2024

Assessing susceptibility for polycyclic aromatic hydrocarbon toxicity in an in vitro 3D respiratory model for asthma

in Developmental and Reproductive Toxicology

Reese M. Valdez
Brianna N. Rivera
Yvonne Chang
Jamie M. Pennington
Kay A. Fischer
Christiane V. Löhr
Susan C. Tilton

Frontiers in Toxicology

doi 10.3389/ftox.2024.1287863

1,694 views
1 citation

Original Research

Published on 17 Apr 2024

The MexTAg collaborative cross: host genetics affects asbestos related disease latency, but has little influence once tumours develop

in Immunotoxicology

Scott A. Fisher
Kimberley Patrick
Tracy Hoang
Elly Marcq
Kiarash Behrouzfar
Sylvia Young
Timothy J. Miller
Bruce W. S. Robinson
Raphael Bueno
Anna K. Nowak

Frontiers in Toxicology

doi 10.3389/ftox.2024.1373003

3,337 views
2 citations

Original Research

Published on 17 Apr 2024

Chemistry domain of applicability evaluation against existing estrogen receptor high-throughput assay-based activity models

in Computational Toxicology and Informatics

Mark D. Nelms
Todor Antonijevic
Caroline Ring
Danni L. Harris
Ronnie Joe Bever
Scott G. Lynn
David Williams
Grace Chappell
Rebecca Boyles
Susan Borghoff

Frontiers in Toxicology

doi 10.3389/ftox.2024.1346767

1,397 views
1 citation

Original Research

Published on 11 Apr 2024

ICH S1 prospective evaluation study: weight of evidence approach to predict outcome and value of 2-year rat carcinogenicity studies. A report from the regulatory authorities subgroup

in Regulatory Toxicology

Todd Bourcier
Timothy McGovern
Tania Cavaliero
Geoffrey Ebere
Akiyoshi Nishikawa
Jihei Nishimura
Kumiko Ogawa
Markku Pasanen
Alisa Vespa
Jan Willem Van der Laan

Frontiers in Toxicology

doi 10.3389/ftox.2024.1353783

4,919 views
6 citations

Original Research

Published on 11 Apr 2024

Use of quantitative in vitro to in vivo extrapolation (QIVIVE) for the assessment of non-combustible next-generation product aerosols

in In Vitro Toxicology

Marjory Moreau
Liam Simms
Melvin E. Andersen
Edgar Trelles Sticken
Roman Wieczorek
Sarah Jean Pour
Fiona Chapman
Karin Roewer
Sandra Otte
Jeffrey Fisher

Frontiers in Toxicology

doi 10.3389/ftox.2024.1373325

3,115 views
5 citations

Review

Published on 09 Apr 2024

New approach methodologies to enhance human health risk assessment of immunotoxic properties of chemicals — a PARC (Partnership for the Assessment of Risk from Chemicals) project

in Immunotoxicology

Igor Snapkow
Nicola M. Smith
Emma Arnesdotter
Karsten Beekmann
Etienne B. Blanc
Albert Braeuning
Emanuela Corsini
Marija Sollner Dolenc
Loes P. M. Duivenvoorde
Gunnar Sundstøl Eriksen

Frontiers in Toxicology

doi 10.3389/ftox.2024.1339104

4,820 views
9 citations

Policy and Practice Reviews

Published on 05 Apr 2024

Developing a pragmatic consensus procedure supporting the ICH S1B(R1) weight of evidence carcinogenicity assessment

in Regulatory Toxicology

Arianna Bassan
Ronald Steigerwalt
Douglas Keller
Lisa Beilke
Paul M. Bradley
Frank Bringezu
William J. Brock
Leigh Ann Burns-Naas
Jon Chambers
Kevin Cross

Frontiers in Toxicology

doi 10.3389/ftox.2024.1370045

3,440 views
5 citations

Perspective

Published on 28 Mar 2024

Digitalization of toxicology: improving preclinical to clinical translation

in Computational Toxicology and Informatics

Brian R. Berridge
Szczepan W. Baran
Vivek Kumar
Natalie Bratcher-Petersen
Michael Ellis
Chang-Ning Liu
Timothy L. Robertson

Frontiers in Toxicology

doi 10.3389/ftox.2024.1377542

3,014 views
2 citations