Frontiers in Toxicology

Original Research

Accepted on 16 Oct 2025

Toxicological assessment of Chlorella vulgaris and its potential preventive effect in a chronic obstructive pulmonary disease (COPD) mouse model

Lucia Giambastiani
Sofia Fiorentino
Kylie Brady
Andrea Raffaelli
Emilia Bramanti
ERNA CECILIA LORENZINI
Vincenzo Longo
Francesca Sparvoli
Luisa Pozzo
Andrea Vornoli

Frontiers in Toxicology

doi 10.3389/ftox.2025.1654583

Original Research

Accepted on 16 Oct 2025

Exposure to the herbicide glyphosate leads to inappropriate threat responses and alters gut microbial composition

Mauricio Cáceres-Chacón
Osmarie Martínez-Guzmán
Héctor A. Haddock-Martínez
Alexdiel Figueroa-Pérez
Sian Rodríguez-Rosado
Jaleniz Suarez-Perez
Raúl Y. Ramos-Sánchez
Filipa Godoy-Vitorino
Demetrio Sierra-Mercado

Frontiers in Toxicology

doi 10.3389/ftox.2025.1704231

Original Research

Published on 15 Oct 2025

A short-term sublethal oral exposure to microcystin-LR disrupts cecal microbiome homeostasis in mallard

Serguei V. Drovetski
Valerie I. Shearn-Bochsler
Erik K. Hofmeister
Natalie K. Karouna-Renier
Robert J. Dusek

Frontiers in Toxicology

doi 10.3389/ftox.2025.1634241

369 views

Original Research

Accepted on 14 Oct 2025

Montmorillonite-Based Essential Oil Carrier and its Effects on Non-Target Species: An Environmental Perspective on its risk assessment

Sofia Machado
Catarina Ganilho
Tatiana Andreani
Rose Marie O. F. Sousa
Artur Ribeiro
Ruth Pereira

Frontiers in Toxicology

doi 10.3389/ftox.2025.1696913

Original Research

Published on 14 Oct 2025

Intravenously administered iron oxide nanoparticles with different coatings reversibly perturb immune cells in peripheral blood without inducing toxicity in mice

Preethi Korangath
Chun-Ting Yang
Sean Healy
Cordula Grüttner
Kathleen Gabrielson
Robert Ivkov

Frontiers in Toxicology

doi 10.3389/ftox.2025.1673416

448 views

Original Research

Accepted on 13 Oct 2025

Comprehensive Methodology for Standardized Ecotoxicological Assessment of TiO2-Based Sunscreen Leachates in Aquatic Environment

Roberta Nugnes
Giulia De Negri Atanasio
Elisabetta Perata
Erica Lertora
Lorenzo Dondero
Federica Robino
Francesca Tardanico
Cristina Capelli
Fabio Ghioni
Tania Cai

Frontiers in Toxicology

doi 10.3389/ftox.2025.1686954

Perspective

Published on 13 Oct 2025

Refining the safety assessment of newly expressed proteins in GMOs

Elena Sánchez-Brunete
Arianna Ferrari
F. Javier Moreno
Tilemachos Goumperis
Michele Ardizzone
Reinhilde Schoonjans
Ian Dewhurst
Ivan Dimitrov
Michelle M. Epstein
Frits Koning

Frontiers in Toxicology

doi 10.3389/ftox.2025.1679506

449 views

Review

Accepted on 10 Oct 2025

Developing an Approach for Evaluating the Cardiotoxic Potential of Botanicals

Julie Krzykwa
Hemantkumar S Chaudhari
Andre Monteiro Da Rocha
Matthias Gossmann
Peter Hoffmann
Yaser Khokhar
Nathan Meyer
Jin Young K Park
Robert Sprando
Ravi Vaidyanathan

Frontiers in Toxicology

doi 10.3389/ftox.2025.1646044

146 views

Original Research

Accepted on 10 Oct 2025

Biological Analysis of Sonchus oleraceus (Linn) Extract and its Effect on Mitigating Sodium Benzoate-Induced Cytotoxicity and Genotoxicity

Maryam Abdulmalik Althubyani
Abdulmajeed Alrefaei
Sameer Hasan Qari
Rayan Saleh Alharbi
Aljawharah Alqathama

Frontiers in Toxicology

doi 10.3389/ftox.2025.1674822

Review

Accepted on 10 Oct 2025

Overall effects of microplastics on brain

Su-jun Fang
Zhao-di Yin
Li-fan Li
Qi Cai
Peng-fei Zheng
Li-zhen Chen

Frontiers in Toxicology

doi 10.3389/ftox.2025.1619096

678 views

Original Research

Accepted on 08 Oct 2025

Toxicological effects of sublethal microcystin-LR exposure in Labeo rohita: histopathological, ultrastructural, immunological, and biochemical impairments

Snatashree Mohanty
Anirban Paul
Rajendran KV
Dr Gayatri Tripathi
Pratap Chandra Das
Pramoda Kumar Sahoo

Frontiers in Toxicology

doi 10.3389/ftox.2025.1658995

155 views

Original Research

Published on 08 Oct 2025

Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework

Jessica Ryman
Richard A. Becker

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657708

1,074 views

Review

Published on 07 Oct 2025

Advancing human health risk assessment: the role of new approach methodologies

Deepika Deepika
Kanchan Bharti
Shubh Sharma
Saurav Kumar
Rajesh Kumar Pathak
Judit Biosca Brull
Oscar Sabuz
Silvia García Vilana
Vikas Kumar

Frontiers in Toxicology

doi 10.3389/ftox.2025.1632941

843 views

Original Research

Accepted on 03 Oct 2025

Toxicological and Nutritional Evaluation of Plant Cell Cultures from Scurvy Grass (Cochlearia danica) and Rowan (Sorbus aucuparia)

Felicianna Felicianna
Ho Lam Cheung
Emily Kwun kwan Lo
Fangfei Zhang
Hoi Kit Matthew Leung
Marsena Jasiel Ismaiah
Natalia Rosa-Sibakov
Valeria Iannone
Carlos Gómez-Gallego
Marjukka Kolehmainen

Frontiers in Toxicology

doi 10.3389/ftox.2025.1655489

214 views

Original Research

Published on 03 Oct 2025

Characterizing chlorotriazine effects in cancer-relevant high-throughput screening assays

Agnes L. Karmaus
Alex Charlton

Frontiers in Toxicology

doi 10.3389/ftox.2025.1682439

472 views

Review

Published on 03 Oct 2025

Pesticides, an urgent challenge to global environmental health and planetary boundaries

Laura N. Vandenberg
Elise J. Pierce
Rachel M. Arsenault

Frontiers in Toxicology

doi 10.3389/ftox.2025.1656297

939 views

574 Publications

Volume 7 - 2025

Toxicological assessment of Chlorella vulgaris and its potential preventive effect in a chronic obstructive pulmonary disease (COPD) mouse model

Exposure to the herbicide glyphosate leads to inappropriate threat responses and alters gut microbial composition

A short-term sublethal oral exposure to microcystin-LR disrupts cecal microbiome homeostasis in mallard

Montmorillonite-Based Essential Oil Carrier and its Effects on Non-Target Species: An Environmental Perspective on its risk assessment

Intravenously administered iron oxide nanoparticles with different coatings reversibly perturb immune cells in peripheral blood without inducing toxicity in mice

Comprehensive Methodology for Standardized Ecotoxicological Assessment of TiO2-Based Sunscreen Leachates in Aquatic Environment

Refining the safety assessment of newly expressed proteins in GMOs

Developing an Approach for Evaluating the Cardiotoxic Potential of Botanicals

Biological Analysis of Sonchus oleraceus (Linn) Extract and its Effect on Mitigating Sodium Benzoate-Induced Cytotoxicity and Genotoxicity

Overall effects of microplastics on brain

Toxicological effects of sublethal microcystin-LR exposure in Labeo rohita: histopathological, ultrastructural, immunological, and biochemical impairments

Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework

Advancing human health risk assessment: the role of new approach methodologies

Toxicological and Nutritional Evaluation of Plant Cell Cultures from Scurvy Grass (Cochlearia danica) and Rowan (Sorbus aucuparia)

Characterizing chlorotriazine effects in cancer-relevant high-throughput screening assays

Pesticides, an urgent challenge to global environmental health and planetary boundaries