Frontiers in Toxicology

Original Research

Accepted on 25 Sep 2025

Intravenously administered iron oxide nanoparticles with different coatings show reversible perturbation of immune cells in peripheral blood with no signs of toxicity in mice

Preethi Korangath
Chun-Ting Yang
Sean Healy
Cordula Grüttner
Kathleen Gabrielson
Robert Ivkov

Frontiers in Toxicology

doi 10.3389/ftox.2025.1673416

Mini Review

Published on 25 Sep 2025

Forensic toxicology of benzodiazepines: neuropharmacological effects, analytical challenges, and emerging detection strategies

Husna Irfan Thalib
Ahmed Abdelghany Damanhory
Ayesha Hanin Shaikh
Shyma Haidar
Sariya Khan
Ayesha Jamal
Omar Ahmed Abdelghany

Frontiers in Toxicology

doi 10.3389/ftox.2025.1639890

138 views

Original Research

Published on 25 Sep 2025

Implementing a trilineage differentiation in the ReproTracker assay for improved teratogenicity assessment

José M. Horcas-Nieto
Sabine Hartvelt
Luke Flatt
Jing Fang
Esther Lam
Gaonan Zhang
Romy Van Vliet
Marleen Feliksik
Tom Zwetsloot
Connor Philippo

Frontiers in Toxicology

doi 10.3389/ftox.2025.1645842

370 views

Original Research

Accepted on 23 Sep 2025

Characterizing Chlorotriazine Effects in Cancer-Relevant High-Throughput Screening Assays

Agnes Karmaus
Alex Charlton

Frontiers in Toxicology

doi 10.3389/ftox.2025.1682439

Original Research

Accepted on 22 Sep 2025

Hospital admissions for acute drug poisoning in adults and children: A seven-year retrospective analysis of hospital discharges at a tertiary center

Daniel Wang
Lina Camacho-Arteaga
Rosario Muñoz Gallarín
Immaculada Danés
Antònia Agustí Escasany

Frontiers in Toxicology

doi 10.3389/ftox.2025.1672470

141 views

Review

Published on 19 Sep 2025

Environmental exposure pathways of microplastics and their toxic effects on ecosystems and the nervous system

Kuo Lu
Yixiang Que
Longfei Wang
Yanfan Wang
Jinyan Qiu
Yangyang Jia
Cong Ding
Dazhong Wang
Weyland Cheng
Yaodong Zhang

Frontiers in Toxicology

doi 10.3389/ftox.2025.1649282

564 views

Original Research

Accepted on 18 Sep 2025

Promoting Ethical and Reproducible Cell Culture: Implementing Animal-Free Alternatives to Teaching in Molecular and Cell Biology

Alexandra Nessar
Viola Röhrs
Mathias Ziersch
Ahmed S.M. Ali
Julia Moradi
Anke Kurreck
Johanna Berg
Jens Kurreck

Frontiers in Toxicology

doi 10.3389/ftox.2025.1670513

216 views

Review

Accepted on 18 Sep 2025

Advancing Human health Risk Assessment: The Role of New Approach Methodology

DEEPIKA DEEPIKA
Kanchan Bharti
Shubh Sharma
Saurav Kumar
Rajesh Kumar Pathak
Judit Biosca Brull
Oscar Sabuz
Silvia García Vilana
Vikas Kumar

Frontiers in Toxicology

doi 10.3389/ftox.2025.1632941

263 views

Review

Accepted on 16 Sep 2025

Excessive Alcohol Consumption: A Driver of Metabolic Dysfunction and Inflammation

Jaeeun Lee
Ji-Young Lee
Hyunju Kang

Frontiers in Toxicology

doi 10.3389/ftox.2025.1670769

987 views

Original Research

Accepted on 15 Sep 2025

A SHORT-TERM SUBLETHAL ORAL EXPOSURE TO MICROCYSTIN-LR DISRUPTS CECAL MICROBIOME HOMEOSTASIS IN MALLARD

Serguei V Drovetski
Valerie Shearn-Bochsler
Erik Hofmeister
Natalie K Karouna- Renier
Robert J Dusek

Frontiers in Toxicology

doi 10.3389/ftox.2025.1634241

162 views

Review

Accepted on 15 Sep 2025

Pesticides, An Urgent Challenge to Global Environmental Health and Planetary Boundaries

Laura N Vandenberg
Elise J Pierce
Rachel M Arsenault

Frontiers in Toxicology

doi 10.3389/ftox.2025.1656297

179 views

Original Research

Published on 15 Sep 2025

Error-corrected next-generation sequencing mutagenicity assays in human HepaRG cells as human-relevant genetic toxicology new approach methodology

A. Rasim Barutcu
Nimisha Bhattarai
Raymond Samuel
Jamie Scaglione
Leslie Recio

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657189

737 views

Original Research

Published on 15 Sep 2025

Daflon and Centrum mitigate vancomycin-induced nephrotoxicity in rats by ameliorating oxidative stress, DNA damage, apoptosis, and inflammation

Hanem F. El-Gendy
Soaad Salamah
Eman Elhusseiny
Hazim O. Khalifa
Hossny A. El-Banna
Taha A. Attia
Shaimaa Selim
Saber El Hanbally

Frontiers in Toxicology

doi 10.3389/ftox.2025.1673083

406 views

Original Research

Accepted on 10 Sep 2025

Integrating 113 Machine Learning Methods to Decipher the Toxicological Mechanisms of Perfluorooctanoic acid in Bladder Cancer

Han Wang
Yang Liu
Aifa Tang

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657251

397 views

Original Research

Accepted on 10 Sep 2025

Rodent home cage monitoring for preclinical safety pharmacology assessment: results of a multi-company validation evaluating nonclinical and clinical data from three compounds

Rowland Radford Sillito
Joanne Sutherland
Aileen Milne
Chiara Giuliano
Carl-Gustav Sigfridsson
Mike Rolf
Ajeesh K Cherian
Michelle L Mcclafferty
Eric I Rossman
Greet B.A. Teuns

Frontiers in Toxicology

doi 10.3389/ftox.2025.1655330

296 views

Original Research

Accepted on 10 Sep 2025

FROM GENES TO ORGANS: PHYSIOLOGICAL RESPONSES OF EUROPEAN CHUB (Squalius cephalus) TO CHRONIC PFAS POLLUTION

Sara Pacchini
Laura Drago
Martina Cortese
Giacomo Vanzan
Elisabetta Piva
Shaghayegh Kholdihaghighi
Andrea Barbarossa
Anisa Bardhi
Sophia Schumann
Chiara Fogliano

Frontiers in Toxicology

doi 10.3389/ftox.2025.1654272

183 views

560 Publications

Volume 7 - 2025

Intravenously administered iron oxide nanoparticles with different coatings show reversible perturbation of immune cells in peripheral blood with no signs of toxicity in mice

Forensic toxicology of benzodiazepines: neuropharmacological effects, analytical challenges, and emerging detection strategies

Implementing a trilineage differentiation in the ReproTracker assay for improved teratogenicity assessment

Characterizing Chlorotriazine Effects in Cancer-Relevant High-Throughput Screening Assays

Hospital admissions for acute drug poisoning in adults and children: A seven-year retrospective analysis of hospital discharges at a tertiary center

Environmental exposure pathways of microplastics and their toxic effects on ecosystems and the nervous system

Promoting Ethical and Reproducible Cell Culture: Implementing Animal-Free Alternatives to Teaching in Molecular and Cell Biology

Advancing Human health Risk Assessment: The Role of New Approach Methodology

Excessive Alcohol Consumption: A Driver of Metabolic Dysfunction and Inflammation

A SHORT-TERM SUBLETHAL ORAL EXPOSURE TO MICROCYSTIN-LR DISRUPTS CECAL MICROBIOME HOMEOSTASIS IN MALLARD

Pesticides, An Urgent Challenge to Global Environmental Health and Planetary Boundaries

Error-corrected next-generation sequencing mutagenicity assays in human HepaRG cells as human-relevant genetic toxicology new approach methodology

Daflon and Centrum mitigate vancomycin-induced nephrotoxicity in rats by ameliorating oxidative stress, DNA damage, apoptosis, and inflammation

Integrating 113 Machine Learning Methods to Decipher the Toxicological Mechanisms of Perfluorooctanoic acid in Bladder Cancer

Rodent home cage monitoring for preclinical safety pharmacology assessment: results of a multi-company validation evaluating nonclinical and clinical data from three compounds

FROM GENES TO ORGANS: PHYSIOLOGICAL RESPONSES OF EUROPEAN CHUB (Squalius cephalus) TO CHRONIC PFAS POLLUTION