1,201 news posts in Mind and body

Health

14 Feb 2023

Cocaine addiction makes the brain age faster, suggests study

By Mischa Dijkstra, Frontiers science writer A new study finds evidence from the DNA methylome that the biological age – different from the chronological age – of cells in Brodmann Area 9 of the prefrontal cortex might be greater in people with cocaine use disorder. This suggests that cocaine abuse makes these cells age faster according to the ‘epigenetic clock’. The authors also find differences in methylation in 20 genes, mainly involved in regulation of the activity of neurons and their connectivity. This post-mortem study is one of the first to directly look at the methylome of brain cells in human subjects with cocaine use disorder, rather than in rodents. Scientists tend to view substance addiction as primarily a disease of the brain. When we enjoy sex, food, music, or hobbies, regions of our brain within the reward pathway are flooded with pleasure-inducing dopamine. Drugs like cocaine copy this effect, except up to ten times more strongly. Healthy brains aren’t at the mercy of such dopamine rushes, however: there, the prefrontal cortex weighs options and can decide to forgo pleasurable activities when it’s not the time or place. In contrast, such ‘inhibitory control’ is impaired in the addicted brain, making […]

Life sciences

13 Feb 2023

European big cat population threatened with extinction as genetics show the population is near collapse

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Eurasian lynxes dispersed across the Swiss border with France in the late 1970s, but the population remains small and fragile. Scientists took genetic samples from lynxes in France and determined that the population’s genetic health is so dangerously tenuous it could be extinct in a generation. Scientists warn that if action isn’t taken soon, the Eurasian lynx will vanish from France. This elusive wild cat, which was reintroduced to Switzerland in the 1970s, moved across the French border by the end of the decade. But a genetic study published in Frontiers in Conservation Science showed that the lynx population in France is in desperate need of help to survive. “Given the rapid loss of genetic diversity, we estimate that this population will go extinct in less than 30 years,” said Nathan Huvier of the Centre Athenas, corresponding author. “This population urgently needs new genetic material to become sustainable.” The missing lynx This population of lynxes, hidden deep within the Jura Mountains, is not well known. Observations by scientists estimate its size at a maximum of 150 adults and suggest that it is poorly connected to larger, healthier populations in Germany and Switzerland, […]

Health

09 Feb 2023

Human test subjects may no longer be needed for mosquito bite trials thanks to invention of new biomaterial

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Studies on mosquito feeding behavior are crucial to fighting malaria, dengue, and other mosquito-borne pathogens – but traditionally, they require humans or animals to act as meals for the mosquitoes. Scientists have developed a biomaterial which mimics skin, right down to blood under the surface, to make studies on mosquito feeding easier to run. Mosquitoes: the world’s deadliest animal. These tiny flying insects are vectors for dengue fever, yellow fever, Zika, malaria, and many other illnesses which affect millions of people around the world, with a significant morbidity and mortality burden. Because they spread disease when they bite people, understanding their feeding behavior is critical to reducing the harm they do. But how to study mosquito feeding behavior without giving them a live meal? A collaboration between Rice University and Tulane University in the US has developed a biomaterial which could eliminate the need for human volunteers or animal subjects in mosquito bite research. “Several groups are dedicated to finding ways to stop mosquitoes from biting, but bringing new repellents to market is challenging,” said Prof Omid Veiseh, Rice University, corresponding author of the study published in Frontiers in Bioengineering and Biotechnology. […]

Humanities

07 Feb 2023

Proof that Neanderthals ate crabs is another ‘nail in the coffin’ for primitive cave dweller stereotypes

by Angharad Brewer Gillham, Frontiers science writer Image: Tomasz Ochocki/Shutterstock.com Scientists studying archaeological remains at Gruta da Figueira Brava, Portugal, discovered that Neanderthals were harvesting shellfish to eat – including brown crabs, where they preferred larger specimens and cooked them in fires. Archeologists say this disproves the idea that eating marine foods gave early modern humans’ brains the competitive advantage. In a cave just south of Lisbon, archeological deposits conceal a Paleolithic dinner menu. As well as stone tools and charcoal, the site of Gruta de Figueira Brava contains rich deposits of shells and bones with much to tell us about the Neanderthals that lived there – especially about their meals. A study published in Frontiers in Environmental Archaeology shows that 90,000 years ago, these Neanderthals were cooking and eating crabs. “At the end of the Last Interglacial, Neanderthals regularly harvested large brown crabs,” said Dr Mariana Nabais of the Catalan Institute of Human Paleoecology and Social Evolution (IPHES-CERCA), lead author of the study. “They were taking them in pools of the nearby rocky coast, targeting adult animals with an average carapace width of 16cm. The animals were brought whole to the cave, where they were roasted on coals and […]

Life sciences

06 Feb 2023

‘Many kids go through a phase where they want to be a marine scientist. For me, it wasn’t a phase’

by Patricia Albano/Angharad Brewer Gillham, Frontiers science writer Patricia stands with remotely operated vehicle Deep Discoverer aboard NOAA Ship Okeanos Explorer during an expedition to explore the deep waters off the West Florida Shelf. Image: Patricia Albano. Marine protected areas are meant to give threatened species space to live and thrive. But in a recent paper in Frontiers in Marine Science, Patricia Albano and colleagues showed that at least one protective area isn’t capturing the range that endangered sharks use as they grow, leaving them vulnerable to commercial fishing. Albano, now the Internship Program Coordinator at the National Marine Sanctuary Foundation, NOAA Ocean Exploration, caught up with Frontiers to tell us a little about her career and her research, as part of our Frontiers Scientist series. Albano’s work focuses on shark ecology in an anthropogenic world and the associated conservation implications. After a BA and MSc from the University of Miami, she joined a project evaluating the efficacy of the De Hoop marine protected area (MPA) for threatened and endemic sharks off South Africa. Albano also dedicates her time to working in ocean education, supporting workforce development programs and efforts to increase diversity, equity, inclusion, and accessibility. In 2020, she […]

Health

01 Feb 2023

Medicines that modify the circadian clock might help heal scars more cleanly

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Scientists determined that compounds which play key roles in both collagen synthesis and circadian management can be used to make wounds on cell samples heal more quickly and effectively, offering promise for treatments to prevent problem scarring in the future. Healing often leaves a scar. But the role of the scar itself in healing is often underestimated: a scar that doesn’t heal cleanly can be painful or upsetting or affect the range of movement of the affected body part. It may even require further surgical treatment. Now, scientists based at the University of California Los Angeles have found that compounds which target the circadian clock and affect the synthesis of collagen — a protein which is important for skin repair — could improve scar healing. “Our aim was to find compounds that were able to increase the rate at which dermal wounds heal while mitigating the formation of hypertrophic scars,” said Dr Akishige Hokugo, corresponding author of a study published to Frontiers in Medicine. “Scars can result in emotional distress following normal wound healing by serving as permanent reminders of the initial incident. Accounting for additional revision procedures, extended hospital stays, and […]

Life sciences

31 Jan 2023

Songbird species work together to mob predator owls, but only strike when the time is right

By Mischa Dijkstra, Frontiers science writer Northern pygmy owl, Glaucidium gnoma. Image credit: W Douglas Robinson Scientists have now shown that songbirds don’t just flee from their predator, the northern pygmy owl: they sometimes actively seek them out to aggressively mob them. But the likelihood of mobbing wasn’t constant: it was highest during late summer and autumn when the owls mostly prey on young birds instead of mammals, and at low altitudes, where the owls are most common. The likelihood of mobbing also increased when there were more songbirds around to dilute the individual risk. The authors conclude that songbirds can tell when the risk of predation from northern pygmy owls is greatest, and mostly ignore these owls at other times of the year. Fleeing isn’t the only way by which songbirds can protect themselves against predators. Many songbird species are known to engage in mobbing, where they gather aggressively around a bird of prey, flying rapidly while making stereotypic movements and loud vocalizations. Mobbing is risky for both parties: birds of preys have been observed to attack their mobbers, while cases are known of birds of prey getting injured by mobbing songbirds. Read original article Download original article (pdf) […]

Health

30 Jan 2023

Five articles you need to check out on the future of surgery

By Colm Gorey, Science Communications Manager Image: Shutterstock.com From robotic surgeons to ultra-detailed imaging technology, the field of surgery is going through rapid change. To help us understand what the latest research is in this world of dissection, Frontiers highlights just some of the top articles we’ve recently published. The robot takeover of the workforce is nowhere more apparent than in the medical world, where many delicate surgical procedures are either aided by a robotic assistant, or in some cases performed entirely by a machine. But advances in surgery are not just limited to robotics, with new imaging technologies helping us peer inside the human body like never before. Here are five recent Frontiers articles published as part of the research topic ‘Anatomical Fundamentals of Advanced Surgical Techniques’ that may greatly influence even more breakthroughs in the future. Robotic pelvic exenteration for gynecologic malignancies, anatomic landmarks, and surgical steps: a systematic review Pelvic exenteration – a surgical operation to remove multiple organs in the pelvis – represents the last resort procedure for patients with advanced primary or recurrent gynecological malignancy, such as endometrial cancer. However, since 2009, the advent of robotic surgery resulted in a new spur to the […]

Health

30 Jan 2023

$1 smart glove could help prevent dangerous births by sensing fetal position

by Conn Hastings, science writer Image/Shutterstock.com Low-resource regions often lack the medical technology to assess when things are going wrong during birth. A new study has revealed an inexpensive sensing glove that can transmit data on fetal position and force applied to the fetal head. The technology could be invaluable in identifying obstructed birth in low-resource regions, providing real-time data on a smartphone app. Can inexpensive technologies provide a helping hand during birth? A new study in open-access journal Frontiers in Global Women’s Health has revealed a low-cost sensing glove that could do just that. The researchers created the device to assist healthcare staff in identifying fetal position and the force applied to the fetal head during labor, factors that can contribute to obstructed labor and poor birth outcomes. The technology can provide real-time data during vaginal examinations, potentially improving birth outcomes in low-resource regions. Birth outcomes in low-resource regions When labor is not going as it should, clinicians can use a wide array of medical technologies to determine what is wrong. However, in low- and middle-income countries, these technologies and skilled staff who can use them are not always available. The researchers behind this latest study reported that 98% […]

Health

25 Jan 2023

Using running to escape everyday stresses may lead to exercise dependence instead of mental wellbeing

By Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Different kinds of escapism can motivate people to take part in running, but using running to escape from negative experiences rather than using it to escape to positive ones may lead to exercise dependence. Recreational running offers a lot of physical and mental health benefits – but some people can develop exercise dependence, a form of addiction to physical activity which can cause health issues. Shockingly, signs of exercise dependence are common even in recreational runners. A study published in Frontiers in Psychology investigated whether the concept of escapism can help us understand the relationship between running, wellbeing, and exercise dependence. “Escapism is an everyday phenomenon among humans, but little is known regarding its motivational underpinnings, how it affects experiences, and the psychological outcomes from it,” said Dr Frode Stenseng of the Norwegian University of Science and Technology, lead author of the paper. Running to explore or to evade? “Escapism is often defined as ‘an activity, a form of entertainment, etc. that helps you avoid or forget unpleasant or boring things’. In other words, many of our everyday activities may be interpreted as escapism,” said Stenseng. “The psychological reward from escapism is […]

Life sciences

24 Jan 2023

‘Golden boy’ mummy was protected by 49 precious amulets, CT scans reveal

By Mischa Dijkstra, Frontiers science writer The ‘Golden boy’ digitally unwrapped, stepwise. Image credit: SN Saleem Scientists used CT scans to ‘digitally unwrap’ the approximately 2,300-year-old undisturbed mummy of a teenage boy of high socioeconomic status. The body was equipped with 49 amulets of 21 different types, many of which were made of gold, which had been carefully placed on or inside the body. These included a two-finger amulet next to the uncircumcised penis, a golden heart scarab placed inside the thoracic cavity, and a golden tongue inside the mouth. He was clad in sandals and garlanded with ferns, with ritual significance. This mummy is a showcase of Egyptian beliefs about death and the afterlife during the Ptolemaic period. The ancient Egyptians believed that when we died, our spiritual body sought out an afterlife similar to this world. But entry into this afterlife wasn’t guaranteed: it first required a perilous journey through the underworld, followed by an individual last judgment. For this reason, relatives and embalmers did everything they could to ensure that their loved one might reach a happy destination. Here, scientists from Egypt used computerized tomography (CT) to ‘digitally unwrap’ the intact, never-opened mummy of a 2,300-year-old teenage […]

Life sciences

19 Jan 2023

Microalgae could be the future of sustainable superfood in a rapidly changing world, study finds

By Peter Rejcek, science writer The global population recently hit eight billion people. Yet climate change and human environmental impacts threaten our long-term food security. Researchers at the University of California, San Diego, recently published a scientific review demonstrating that microalgae and other microscopic, plant-like organisms could help feed the world’s growing population more sustainably than current agricultural systems. Algae. It’s what’s for dinner. This variation on the iconic US advertising slogan from the beef industry may sound funny, but it’s no joke that the current agriculture system is a major source of greenhouse gas emissions and environmental pollution. In turn, the climate crisis and ecosystem degradation threaten long-term food security for billions of people around the world. Researchers at the University of California, San Diego (UCSD), believe algae could be a new kind of superfood thanks to its high protein and nutrition content. They make their case in a paper recently published in the journal Frontiers in Nutrition that examines the current scientific literature on microalgae, a catch-all term for the thousands of microscopic algal species and other photosynthetic organisms like cyanobacteria found in various aquatic environments. A more efficient food source The review highlights the current technologies for […]

Health

17 Jan 2023

Healthy Eating: Article Collections on Nutrition

What is a healthy diet? Is gluten free actually better for you? Are there good fats? Find the answers to your biggest research questions on nutrition with our top article collections about what to put on your plate. With collective views of over 1.2 million, researchers explored topics spanning from antioxidants and food additives to sustainable diets and the rise of flexitarianism. Article Collections: Mediterranean diet 4 articles | 62,000 views Uncovering the health promoting effects of traditional Mediterranean diets, including lower risk of chronic degenerative diseases, neurodegenerative disorders, and certain types of cancer Sustainable diets 43 articles | 90,000 views Examining a diet that is measured by calorie or nutrient content as well as by the quality and environmental footprint of the ingredients used Flexitarianism 6 articles | 167,000 views Exploring the health implications of flexitarianism, referring to an individual who follows a primarily but not strictly vegetarian diet, occasionally eating meat or fish Fermented foods 19 articles | 190,000 views Understanding the viability of probiotic bacteria in fermented foods has opened up possibilities of producing new ingredients for nutritionally optimized foods, which can promote consumers’ health through microbial activities in the gut Dietary antioxidants 6 articles | 41,000 […]

Health

17 Jan 2023

From pylons to pandas: 5 Frontiers articles you won’t want to miss

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com At Frontiers, we bring some of the world’s best research to a global audience. But with tens of thousands of articles published each year, many often fly under the radar. Here are just five amazing papers you may have missed. Building better-looking pylons Pylons help support essential amenities – but they can be an eyesore. Italian scientists led by Dr Luca Di Angelo at University of L’Aquila investigated the best way to build a pylon with less visual impact on the landscape. As visual impact is subjective, reducing it requires consultation with residents who will see the pylons every day. But designs invented by residents without technical knowledge may not be able to meet safety standards. Di Angelo and colleagues used the development of new electrical pylons in the coastal regions of Italy to test a novel method of integrating visual impact minimization with the design process. They identified shapes which were related to the geography and culture of the area and streamlined enough for pylon design, and surveyed Italians from different coastal regions to determine which shapes were considered most recognizable and representative. A sail was chosen, and models were developed […]

Life sciences

16 Jan 2023

Our toilets can yield excellent alternatives for widespread polluting fertilizers

By Mischa Dijkstra, Frontiers science writer Scientists show that the yield of cabbages grown on soils supplied with two modern nitrified urine fertilizers recycled from human urine is approximately equal to the yield when soils are fertilized with commercial vinasse. The exclusive use of compost recycled from human feces gave a slightly lower yield, but such compost is expected to give extra carbon to soils when combined with nitrified urine fertilizers. Importantly, pharmaceuticals in feces ended up in the edible plant parts only in negligible amounts, implying that fertilizers recycled from human excreta are not only productive but also safe. To tackle the climate crisis, biodiversity loss, and pollution, humanity will need to move to a circular economy, where all resources are recycled. Why not recycle our own body waste too as fertilizer, provided there is no risk that harmful microbes or traces from pharmaceuticals end up in the consumed crops? Most nutrients needed for plant growth occur in human urine and feces. Urine is especially rich in nitrogen and potassium, and also contains trace amounts of metals such as boron, zinc, and iron. Feces could in theory supply other nutrients such as phosphorus, calcium, and magnesium or valuable organic […]