1,222 news posts in Mind and body

Health

30 Nov 2022

Biomarker in urine could be the first to reveal early-stage Alzheimer’s disease

By Conn Hastings, science writer Image: BlurryMe/Shutterstock.com Alzheimer’s disease can remain undetected until it is too late to treat. Large-scale screening programs could help to detect early-stage disease, but current diagnostic methods are too cumbersome and expensive. A new study published to Frontiers is the first to identify formic acid as a sensitive urinary biomarker that can reveal early-stage Alzheimer’s disease, potentially paving the way for inexpensive and convenient disease screening. Could a simple urine test reveal if someone has early-stage Alzheimer’s disease and could this pave the way for large-scale screening programs? A new study in Frontiers in Aging Neuroscience certainly suggests so. The researchers tested a large group of patients with Alzheimer’s disease of different levels of severity and healthy controls with normal cognition to identify differences in urinary biomarkers. They found that urinary formic acid is a sensitive marker of subjective cognitive decline that may indicate the very early stages of Alzheimer’s disease. Current methods to diagnose Alzheimer’s are expensive, inconvenient, and unsuitable for routine screening. This means that most patients only receive a diagnosis when it is too late for effective treatment. However, a non-invasive, inexpensive, and convenient urine test for formic acid could be […]

Psychology

24 Nov 2022

How you help a child go to sleep is related to their behavioral development, finds new study

By Suzanna Burgelman, Frontiers science writer Image: yamasan0708/Shutterstock.com A group of international researchers examined parental methods to help toddlers sleep across 14 cultures and found that these methods are related to the development of a child’s temperament. The researchers suggested focusing on better sleep-related parenting practices to support positive behavioral development across cultures. The importance of good sleep during childhood development has been extensively researched. Bad sleep quality and behaviors are detrimental to neurobehavioral functioning, emotional reactivity and regulation, and can pose a risk for future psychopathology. “Parental sleeping techniques are correlated with children’s sleep quality, and the importance of cultural context in child development has been long recognized,” said corresponding author Ms Christie Pham, of Washington State University. “We wanted to examine whether cross-cultural differences in parental sleep-supporting strategies account for differences in toddler temperament.” In a study published in Frontiers in Psychology, Pham and her colleagues studied the effect of different parental sleep-supporting techniques on child temperament across 14 cultures. They hypothesized that passive ways of helping a child fall asleep (eg, cuddling, singing, and reading), but not active methods (eg, walking, car rides, and playing), would be positively related to a child’s temperament. ► Read original article► Download original […]

Life sciences

23 Nov 2022

World’s heaviest flying bird may be self-medicating on plants used in traditional medicine

By Mischa Dijkstra, Frontiers science writer Great bustard male displaying on lek. Image credit: Carlos Palacín Researchers show that great bustards in Spain prefer to eat two plant species with compounds active in vitro against protozoa, nematodes, and fungi: corn poppies and purple viper’s bugloss. Males, who spend much time and energy on sexual displays during the mating season, have a stronger preference for these plants than females, and more so during the mating season than at other times of the year. The authors thus consider great bustards as prime candidates for non-human animals that self-medicate, but stress that more research is needed to definitively prove this. If you see a great bustard (Otis tarda) in the wild, you’re unlikely to forget it. Massive, colorful, and impossible to mistake, they are the heaviest birds living today capable of flight, with the greatest size difference between the sexes. They are also ‘lek breeders’, where males gather at chosen sites to put on an audiovisual show for the visiting females, who choose a mate based on his appearance and the quality of his showbirdship. But now, a study in Frontiers in Ecology and Evolution suggests that great bustards have another claim to […]

Health

15 Nov 2022

Balancing blood sugar: article collections on Diabetes

To mark World Diabetes Week, we have gathered our top article collections on Diabetes. With collective views of over 1.1 million, researchers explored topics spanning from stem cell technology for modelling Diabetes and the use of low carbohydrate diets for prevention to integrating digital health technologies in a patient-centered care framework and promising new therapeutic approaches in cardiovascular disease for diabetics. Article collections: Heart health 11 articles | 79,000 views Exploring the intimate relationship between cardiovascular disease and diabetes mellitus, highlighting key opportunities that may lead to promising new therapeutic approaches Alzheimer’s disease 6 articles | 80,000 views More than 35 million patients suffer from dementia, while 380 million battle against diabetes in this aging society. Emerging evidence suggests that diabetes increases the risk of dementia; however, the underlying mechanisms remain to be fully elucidated Patient Care 10 articles | 95,000 views Addressing the challenging and complex issues with Diabetes care, including improving and achieving effective and efficient care at the primary care setting as well as integrating digital health technologies in a patient-centered care framework Nutrition 7 articles | 79,000 views Examining the use of low carbohydrate diets, with or without nutritional ketosis, for the prevention and treatment of […]

Life sciences

11 Nov 2022

Having good friendships may make for a healthier gut microbiome

By Mischa Dijkstra, Frontiers science writer Grooming rhesus macaques on Cayo Santiago. Image credit: Lauren Brent Researchers show for the first time that monkeys that are more sociable – eg, grooming or being groomed more often, and with more grooming partners – have a healthier gut microbiome. For example, they have more of the beneficial bacteria Faecalibacterium and Prevotella, and fewer of the typically pathogenic bacteria Streptococcus. This is further evidence that in primates, social connectedness translates into good physical and mental health, and vice versa. Social connections are essential for good health and wellbeing in social animals, such as ourselves and other primates. There is also increasing evidence that the gut microbiome – through the so-called ‘gut-brain axis’ – plays a key role in our physical and mental health and that bacteria can be transmitted socially, for example through touch. So how does social connectedness translate into the composition and diversity of the gut microbiome? That’s the topic of a new study in Frontiers in Microbiology on rhesus macaques, Macaca mulatta. Lead author Dr Katerina Johnson, a research associate at the Department of Experimental Psychology and the Department of Psychiatry of the University of Oxford, said: “Here we show […]

Life sciences

04 Nov 2022

From ghost gear to microbe memories: 4 Frontiers articles you won’t want to miss

by Angharad Brewer Gillham, Frontiers science writer Image: Shutterstock.com At Frontiers, we bring some of the world’s best research to a global audience. But with tens of thousands of articles published each year, many often fly under the radar. Here are just four amazing papers you may have missed. The hunt for ghost gear 25-30% of the plastic waste in the sea is lost fishing gear, or ‘ghost gear’, some of it now up to 60 years old. This ghost gear devastates the environment not only through continuing to trap fish, but also by shedding microplastics into the environment which then enter the food chain. Once it sinks as far as the sea floor, it becomes invisible from above – a hidden threat to the marine ecosystem. A team led by Andrea Stolte from the World Wildlife Foundation, writing in Frontiers in Marine Science, reported a successful ghost-hunting collaboration between fisherfolk, scientists, and divers in the Baltic Sea. This coalition of stakeholders had several options for hunting down the ghost gear. Traditionally, when lost gear is spotted, fisherfolk use search hooks and other similar tools to try to retrieve it. However, this proved to be inefficient and damaging to the […]

Life sciences

02 Nov 2022

Italian researchers discover new recipe for extending shelf life of fresh pasta by 30 days

By Peter Rejcek, science writer Image credit: Raimunda Losantos / Shutterstock.com Pasta is one of the most popular food staples in the world, but fresh pasta has a limited shelf life. Scientists in Italy have cooked up a novel process for preventing or delaying spoilage by changing packaging protocols, as well as adding antimicrobial probiotics to the dough. Not only does this new method extend storage of fresh pasta by 30 days, it helps reduce food waste. Pasta is serious business in Italy, with reportedly more than 300 specific forms known by some 1,300 names. There is even a 55-year-old ‘pasta law’ that governs its production and manufacture. But that doesn’t mean the beloved food staple is shut off from innovation. ► Read original article► Download original article (pdf) Now, Italian researchers have cooked up a new process for extending the shelf life of fresh pasta by 30 days, using a novel packaging process that also involves applying bioprotective probiotic cultures to the dough. They published this new recipe for better preserving fresh pasta in the journal Frontiers in Microbiology. The problem with fresh pasta Most fresh pasta sold in stores today is produced through an industrial process that includes heat-treating the […]

Humanities

26 Oct 2022

‘Virtual autopsy’ identifies a 17th century mummified toddler hidden from the sun

by Angharad Brewer Gillham, Frontiers science writer Image: Riderfoot/Shutterstock.com Scientists used a ‘virtual autopsy’ to examine the mummy of a child found in an aristocratic family crypt, revealing him most probably as Reichard Wilhelm (1625-1626). Despite his wealthy background, the child experienced extreme nutritional deficiency and a tragically early death from pneumonia. A team of scientists based in Germany have examined a 17th century child mummy, using cutting-edge science alongside historical records to shed new light on Renaissance childhood. The child was found in an aristocratic Austrian family crypt, where the conditions allowed for natural mummification, preserving soft tissue that contained critical information about his life and death. Curiously, this was the only unidentified body in the crypt, buried in an unmarked wooden coffin instead of the elaborate metal coffins reserved for the other members of the family buried there. The team, led by Dr Andreas Nerlich of the Academic Clinic Munich-Bogenhausen, carried out a virtual autopsy and radiocarbon testing, and examined family records and key material clues from the burial, to try to understand who the child was and what his short life looked like. “This is only one case,” said Nerlich, lead author of the paper published today […]

Life sciences

24 Oct 2022

CO2 ventilation breakthrough could turn city rooftops into bumper vegetable gardens

by Angharad Brewer Gillham, Frontiers science writer Image: Shutterstock.com Scientists find that expelled air from ventilation systems can make corn and spinach grow taller and larger, recycling CO2-rich indoor air to fertilize edible plants. As the world’s cities grow, the hunt is on for ways to make them greener, more sustainable, and more livable. Rooftop farms and gardens that take advantage of underutilized roof space are a popular option, providing new food resources while simultaneously cooling the surrounding area, increasing building insulation, and improving air quality. But the conditions on rooftops — greater solar radiation, more wind exposure, lesser soil moisture — often mean that plants are smaller and less healthy. A team led by Dr Sarabeth Buckley, now at the University of Cambridge, theorized that repurposing the CO2 from building exhaust as a kind of fertilizer might help counter some of these challenges. To explore this, they grew corn and spinach on the roof of a campus building at Boston University. “We wanted to test whether there is an untapped resource inside buildings that could be used to make plants grow larger in rooftop farms,” said Buckley, whose team named their experimental garden BIG GRO and published their work […]

Life sciences

21 Oct 2022

Secret behind spectacular blooms in world’s driest desert is invisible to human eyes

By Mischa Dijkstra, Frontiers science writer The 2021 ‘desierto florido’ near Caldera, Chile. The purple flowers are the pussypaw Cistanthe longiscapa (family Montiaceae), the object of this study. Image credit: Oven Pérez-Nates A ‘desierto florido’ mass bloom happened in the northern Atacama desert in 2021, which was even visible from space. Researchers used advanced imaging techniques to measure the variation in flower color and pattern for the dominant species, the pussypaw Cistanthe longiscapa. They found that this variation is much greater when viewed by the UV-sensitive eyes of hymenopteran pollinators, and caused by differences in the mix of betalain pigments in the petals. Evolution is probably ongoing, driven by the species-specific visual preferences of pollinators, which could ultimately lead to new species. The Atacama desert, which stretches for approximately 1,600 km along the western coast of the cone of South America, is the driest place on Earth. Some weather stations there have never recorded rainfall throughout their existence. But it‘s far from barren: many species live here that occur nowhere else, adapted to its extreme conditions. And approximately every five to 10 years, from September to mid-November, the Atacama hosts one of the most spectacular sights of the natural world: […]

Life sciences

07 Oct 2022

Scientists peel back ancient layers of banana DNA to reveal mystery ancestors

By Mischa Dijkstra, Frontiers science writer Researchers compare the genomes of more than 200 wild and domesticated varieties of bananas and show that three extra ancestors, either subspecies or distinct species, must have been involved in the domestication process. They also deduce the geographic regions in Australasia where these mystery ancestors lived. If they haven’t gone extinct, they are likely threatened and it’s urgent to find and protect them, to preserve genetic diversity that could help breed better bananas. Bananas are thought to have been first domesticated by people 7,000 years ago on the island of New Guinea. But the domestication history of bananas is complicated, while their classification is hotly debated, as boundaries between species and subspecies are often unclear. Now, a study in Frontiers in Plant Science shows that this history is even more complex than previously thought. The results confirm that the genome of today’s domesticated varieties contains traces of three extra, as yet unknown ancestors. ► Read original article► Download original article (pdf) “Here we show that most of today’s diploid cultivated bananas that descend from the wild banana M. acuminata are hybrids between different subspecies. At least three extra wild ‘mystery ancestors’ must have contributed to this […]

Health

30 Sep 2022

‘Love hormone’ revealed to have heart healing properties

By Mischa Dijkstra, Frontiers science writer Image: Shutterstock.com Researchers show for the first time that the neurohormone oxytocin has a previously unsuspected function in both zebrafish and human cell cultures: it stimulates mature cells in the epicardium of the heart to become stem-like cells, which can replace heart cells lost after damage. This discovery could one day be used to stimulate the regeneration of the human heart after a heart attack. The neurohormone oxytocin is well-known for promoting social bonds and generating pleasurable feelings, for example from art, exercise, or sex. But the hormone has many other functions, such as the regulation of lactation and uterine contractions in females, and the regulation of ejaculation, sperm transport, and testosterone production in males. Now, researchers from Michigan State University show that in zebrafish and human tissue cultures, oxytocin has yet another, unsuspected, function: it stimulates stem cells derived from the heart’s outer layer (epicardium), to migrate into its middle layer (myocardium) and there develop into cardiomyocytes, muscle cells that generate heart contractions. This discovery could one day be used to promote the regeneration of the human heart after a heart attack. The results are published in Frontiers in Cell and Developmental Biology. […]

Health

27 Sep 2022

4 articles you need to check out on the future of behavioral neuroscience

By Angharad Brewer Gillham, Frontiers science writer Image: Shutterstock.com How mice and rats help study depression Mice and rats are key model animals that help us understand how depression works and how to treat it. A huge number of people around the world live with this devastating disorder, but its causes and symptoms are so varied that it is hard to test new treatments and to reproduce experiments to prove those treatments work. Scientists writing in Frontiers in Behavioral Neuroscience reviewed the evidence for rodent models of depression and found that models imitating social stress or a disrupted early life have had some success. Meanwhile, models with behavioral stressors designed to induce helplessness are easily compared to other labs’ work but aren’t complex enough to model depression. A key element of depression is anhedonia, struggling to enjoy life, but this is extremely difficult to model in nonhuman animals. The most popular options available test preference for sweet tastes. The team concluded that the best option is to provide mice with a more naturalistic setting to live in, with more space to socialize and to follow their own inclinations. This helps avoid experimenter influence and allows spontaneous behavior from the mice […]

Life sciences

27 Sep 2022

Sugary poo could be used to lure destructive plant pests to their doom

By K.E.D. Coan, science writer Aggregation of spotted lanternflies, Lycorma delicatula. Image credit: Jana Shea / Shutterstock.com Spotted lanternflies send signals with their honeydew excretions, shows a new study. Scientists are researching how this damaging invasive species communicates in order to better manage the pest problem. This research provides knowledge of how these insects find each other, as well as the first evidence to show that these signals appear sex-specific. Spotted lanternflies communicate through their smelly excretions, called honeydew, reports a new study in Frontiers in Insect Science. This invasive species has been impacting crops in the northeastern US, but little is known about how these insects locate each other for reproduction or feeding. According to this latest research, the insects’ honeydew emits several airborne chemicals that attract other lanternflies. Surprisingly, these effects are sex-specific, which may be the first known case of such signals in insects known as planthoppers. “This research is important because the first step to managing any pest is to understand their biology and behavior,” said Dr Miriam Cooperband of the United States Department of Agriculture Animal and Plant Health Inspection Service, Plant Protection and Quarantine Division (USDA APHIS PPQ) in the US. “As we learn […]

Health

26 Sep 2022

New research shows self-injectable contraception can enable women to take charge of their reproductive health

By Allen Namagembe, PATH, Uganda and Dr Jane Cover, PATH, US Image: PATH/Will Boase Allen Namagembe is a clinical epidemiologist, a biostatistician, and a global expert on self-injection. She is the Uganda Deputy Project Director and M&E Lead on the Uganda Self-Injection Scale-Up project at PATH. Dr. Jane Cover is a Research and Evaluation Manager on PATH’s Sexual and Reproductive Health team and the PATH-JSI DMPA-SC Access Collaborative. Now, they explain their team’s two studies, published in Frontiers in Global Women’s Health, where they used a human-centered design approach to develop and implement a pilot self-injection program in Uganda. Their results show how the program can increase women’s contraceptive access and options. For some, the term ‘self-care’ might conjure up images of skincare routines, bubble baths, and meditation. But in public health, self-care refers to the ability of individuals to self-manage aspects of their health care with the goal of promoting and sustaining health, preventing disease, and managing illness or disability. Grounded in evidence, agency, and equity, self-care interventions are key components of a holistic primary health care system and can help fill gaps in access to essential health services. We both conduct research in the sexual and reproductive health […]