Immunomodulatory Natural Products - their Pharmacological and Therapeutic potential

9,642
Total downloads
38k
Total views and downloads

Articles

ORIGINAL RESEARCH

Published on 06 Aug 2025

Jing Guan Fang, an herbal formula, as an immunomodulator: opposing effects on basal and lipopolysaccharide-induced inflammation of macrophage via JAK/STAT3 and MAPK pathways

Zhi-Hu Lin
Hsin Yeh
Sang-Nguyen-Cao Phan
Li-Lan Liao
Chien-Chang Chen
Wei-Hung Hsu
Chung-Hua Hsu
Tung-Yi Lin

doi 10.3389/fphar.2025.1618488

961 views

ORIGINAL RESEARCH

Published on 01 Aug 2025

Dihydroartemisinin decreases pre-existing neutralizing antibodies against adeno-associated virus in challenged mice

Jingjing Fang
Enze Cui
Jinyan Xie
Xuxia Gao
Yun He
Ming Yang
Sana Shaheen
Zhengjun Zhou
Shaolai Zhou
2 more
Chen Ling

doi 10.3389/fphar.2025.1587135

762 views

ORIGINAL RESEARCH

Published on 09 Jul 2025

Anti-inflammatory and anticancer properties of Alcea rosea extracts: Insights from in vitro and in vivo studies

Ruhban Ansar Parry
Sajad Hamid Wani
Irfan Ahmad Mir
Basharat Ahmad Bhat
Mahboob Ul Hussain
Mushtaq Ahmad Mir
Nasreena Bashir
Abdalla N. Fadul
Surender Jangra
1 more
Showkat Ahmad Ganie

doi 10.3389/fphar.2025.1595604

1,040 views

REVIEW

Published on 23 Jun 2025

Unveiling the role of erinacines in the neuroprotective effects of Hericium erinaceus: a systematic review in preclinical models

E. T. Spangenberg
A. Moneypenny
G. G. Bozzo
M. L. Perreault

doi 10.3389/fphar.2025.1582081

1,884 views

REVIEW

Published on 08 May 2025

A comprehensive review of natural products in rheumatoid arthritis: therapeutic potential and mechanisms

Yuli Han
Shujing Chen
Changqing Liu
Huihui Sun
Zhaoyu Jia
Jiaxin Shi
Jin Li
Yanxu Chang

doi 10.3389/fimmu.2025.1501019

2,230 views

ORIGINAL RESEARCH

Published on 23 Apr 2025

Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses

Chengyu Yang
Ya Xu
Fenfang Gong
Silu Li
Huang Zhan
Zhixuan Huang
Maolin Wang
Hui Li
Hengjun Huang

doi 10.3389/fphar.2025.1565451

1,228 views
1 citation

ORIGINAL RESEARCH

Published on 10 Mar 2025

Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway

Zulipikaer Wusiman
Ai-Mei Zhang
Shu-Shu Zhang
Ping-Ping Zhao
Yu-Tong Kang
Yun Zhang
Zhi-Jian Li
Shi-Xia Huo

doi 10.3389/fphar.2025.1521097

1,772 views

ORIGINAL RESEARCH

Published on 18 Feb 2025

Monotropein inhibits epithelial–mesenchymal transition in chronic colitis via the mTOR/P70S6K pathway

Yuanfan Chen
Jiaying Liu
Shaowen Zhong
Tianwu Zhang
Jin Yuan
Jing Zhang
Ying Chen
Jian Liang
Yonger Chen
2 more
Jie Gao

doi 10.3389/fphar.2025.1536091

1,544 views

ORIGINAL RESEARCH

Published on 14 Feb 2025

A bibliometric and visualization analysis of the role of traditional Chinese medicine in cancer immunotherapy

Yixiao Lian
Jie Sun
Lin Yang
Weidong Yu

doi 10.3389/fimmu.2025.1499026

4,101 views
2 citations

SYSTEMATIC REVIEW

Published on 03 Feb 2025

Comparative efficacy of topical commercial Chinese polyherbal preparation for vulvovaginal candidiasis: a network meta-analysis

Lizheng Wu
Shangwen Jing
Na Li
Dandan Cao
Fangli Pei
Yantong Luo
Xiaoxin Chen
Yingjie Huang
Cheng Zeng

doi 10.3389/fphar.2025.1484325

1,521 views

ORIGINAL RESEARCH

Published on 09 Dec 2024

Quercetin alleviates ulcerative colitis through inhibiting CXCL8-CXCR1/2 axis: a network and transcriptome analysis

Zhangyu Jiang
Mingjuan Yan
Yanmi Qin
Zhenglin Liu
Yilin Duan
Yingju Wang
Ruisen Zhang
Wenjia Lin
Yanwu Li
1 more
Junyu Ke

doi 10.3389/fphar.2024.1485255

1,595 views

ORIGINAL RESEARCH

Published on 22 Oct 2024

Effects of cannabidiol on AMPKα2 /HIF-1α/BNIP3/NIX signaling pathway in skeletal muscle injury

Zhiquan Hou
Zhifang Wang
Jun Zhang
Yunen Liu
Zhonghua Luo

doi 10.3389/fphar.2024.1450513

1,977 views

Share on

Frontiers in Pharmacology

Ethnopharmacology

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

Impact

38kTopic views
26kArticle views
9,642Article downloads

View impact

Articles

Jing Guan Fang, an herbal formula, as an immunomodulator: opposing effects on basal and lipopolysaccharide-induced inflammation of macrophage via JAK/STAT3 and MAPK pathways

Dihydroartemisinin decreases pre-existing neutralizing antibodies against adeno-associated virus in challenged mice

Anti-inflammatory and anticancer properties of Alcea rosea extracts: Insights from in vitro and in vivo studies

Unveiling the role of erinacines in the neuroprotective effects of Hericium erinaceus: a systematic review in preclinical models

A comprehensive review of natural products in rheumatoid arthritis: therapeutic potential and mechanisms

Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses

Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway

Monotropein inhibits epithelial–mesenchymal transition in chronic colitis via the mTOR/P70S6K pathway

A bibliometric and visualization analysis of the role of traditional Chinese medicine in cancer immunotherapy

Comparative efficacy of topical commercial Chinese polyherbal preparation for vulvovaginal candidiasis: a network meta-analysis

Quercetin alleviates ulcerative colitis through inhibiting CXCL8-CXCR1/2 axis: a network and transcriptome analysis

Effects of cannabidiol on AMPKα2 /HIF-1α/BNIP3/NIX signaling pathway in skeletal muscle injury

Frontiers in Pharmacology

Ethnopharmacology