Unveiling the Next Generation of Cancer Immunity & Immunotherapy

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ORIGINAL RESEARCH

Published on 31 Jul 2025

Dual targeting of BCMA and SLAMF7 with the CARtein system: chimeric antigen receptors with intein-mediated splicing elicit specific T cell activation against multiple myeloma

Noelia Moares
Pablo Gonzalez-Garcia
Wenjie Yi-He
Juan P. Muñoz-Miranda
Antonio Gabucio
Rosa Luna-Espejo
Javier Ocaña-Cuesta
Ricardo Fernandez-Cisnal
Cecilia M. Fernandez-Ponce
Francisco Garcia-Cozar

doi 10.3389/fimmu.2025.1613222

987 views

CASE REPORT

Published on 22 Jul 2025

Case Report: Personalized peptide-based immunization in an advanced-stage prostate cancer patient with bone metastasis

Nils Heinrich Thoennissen
Mari Carmen Martos-Contreras
Mehdi Manoochehri
Mauro Nogueira
Franziska Bremm
Jan Dörrie
Jan Christoph
Meik Kunz
Wolfgang Schönharting

doi 10.3389/fonc.2025.1596315

640 views

ORIGINAL RESEARCH

Published on 16 May 2025

Effect of bispecific recombinant oncolytic adenovirus carrying apoptin on apoptosis of MCF-7 cells

Shuang Chen
Wenyao Li
Xunzhe Yin
Cheng Hu
Yiquan Li
Xiaotong Shao
Xiao Li
Ningyi Jin

doi 10.3389/fimmu.2025.1530583

1,172 views

REVIEW

Published on 17 Apr 2025

Revisiting the role of cancer-associated fibroblasts in tumor microenvironment

Xiaolei Lan
Wenyang Li
Kai Zhao
Jianpeng Wang
Shifang Li
Hai Zhao

doi 10.3389/fimmu.2025.1582532

2,986 views
4 citations

REVIEW

Published on 11 Apr 2025

Immune microenvironment of tumor-draining lymph nodes: insights for immunotherapy

Jiahuan Wei
Daozhang Li
Haixia Long
Mei Han

doi 10.3389/fimmu.2025.1562797

2,298 views

REVIEW

Published on 19 Feb 2025

Expanding the horizon of CAR T cell therapy: from cancer treatment to autoimmune diseases and beyond

Zishan Yang
Bingjun Ha
Qinhan Wu
Feng Ren
Zhinan Yin
Hongru Zhang

doi 10.3389/fimmu.2025.1544532

4,636 views
1 citation

REVIEW

Published on 25 Nov 2024

B7-H3 in glioblastoma and beyond: significance and therapeutic strategies

Davor Babič
Ivana Jovčevska
Alja Zottel

doi 10.3389/fimmu.2024.1495283

4,825 views
3 citations

ORIGINAL RESEARCH

Published on 21 Nov 2024

Global trends and research hotspots in perioperative management of lung cancer: a bibliometric analysis from 2004 to 2024

Qinling Jiang
Zhuheng Wei
Pingping Liu
Zonghuai Li
Huiqin Jiang
Yilin Cao
Bo Zhang
Yuanyuan Yan
Yulong He

doi 10.3389/fimmu.2024.1500686

1,830 views
2 citations

ORIGINAL RESEARCH

Published on 20 Nov 2024

Discovery and preclinical evaluation of BPB-101: a novel triple functional bispecific antibody targeting GARP-TGF-β complex/SLC, free TGF-β and PD-L1

Wenxin Xu
Jieying Xu
Pingcui Li
Deyu Xu
Hongjie Cheng
Huan Zheng
Li Zhang
Mengmeng Liu
Siyuan Ye
3 more
Lieming Ding

doi 10.3389/fimmu.2024.1479399

1,983 views
1 citation

CASE REPORT

Published on 01 Nov 2024

Local radiotherapy in extensive-stage small-cell lung cancer sustainably boosts the clinical benefit of first-line immunotherapy: a case report

Hongming Wang
Nuoni Wang
Shiyan Li
Yangfeng Du
Tao Wu
Wei Tian
Wen Dong
Xiaoyang Liu
Yan Zhang
2 more
Zhijun Wu

doi 10.3389/fimmu.2024.1493740

4,885 views
1 citation

REVIEW

Published on 30 Oct 2024

Oncolytic viruses: a potential breakthrough immunotherapy for multiple myeloma patients

Vincenzo Raimondi
Rosanna Vescovini
Mattia Dessena
Gaetano Donofrio
Paola Storti
Nicola Giuliani

doi 10.3389/fimmu.2024.1483806

2,672 views
2 citations

ORIGINAL RESEARCH

Published on 19 Sep 2024

High specificity of engineered T cells with third generation CAR (CD28-4-1BB-CD3-ζ) based on biotin-bound monomeric streptavidin for potential tumor immunotherapy

Jorge Gallego-Valle
Verónica Astrid Pérez-Fernández
Jesús Rosales-Magallares
Sergio Gil-Manso
María Castellá
Europa Azucena Gonzalez-Navarro
Rafael Correa-Rocha
Manel Juan
Marjorie Pion

doi 10.3389/fimmu.2024.1448752

2,525 views

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Frontiers in Immunology

Cancer Immunity and Immunotherapy

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Frontiers in Oncology
- Cancer Immunity and Immunotherapy
- 3.3 impact factor
- 6.9 citescore

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Articles

Dual targeting of BCMA and SLAMF7 with the CARtein system: chimeric antigen receptors with intein-mediated splicing elicit specific T cell activation against multiple myeloma

Case Report: Personalized peptide-based immunization in an advanced-stage prostate cancer patient with bone metastasis

Effect of bispecific recombinant oncolytic adenovirus carrying apoptin on apoptosis of MCF-7 cells

Revisiting the role of cancer-associated fibroblasts in tumor microenvironment

Immune microenvironment of tumor-draining lymph nodes: insights for immunotherapy

Expanding the horizon of CAR T cell therapy: from cancer treatment to autoimmune diseases and beyond

B7-H3 in glioblastoma and beyond: significance and therapeutic strategies

Global trends and research hotspots in perioperative management of lung cancer: a bibliometric analysis from 2004 to 2024

Discovery and preclinical evaluation of BPB-101: a novel triple functional bispecific antibody targeting GARP-TGF-β complex/SLC, free TGF-β and PD-L1

Local radiotherapy in extensive-stage small-cell lung cancer sustainably boosts the clinical benefit of first-line immunotherapy: a case report

Oncolytic viruses: a potential breakthrough immunotherapy for multiple myeloma patients

High specificity of engineered T cells with third generation CAR (CD28-4-1BB-CD3-ζ) based on biotin-bound monomeric streptavidin for potential tumor immunotherapy

Frontiers in Immunology

Cancer Immunity and Immunotherapy

Participating Journals

Frontiers in Oncology

Cancer Immunity and Immunotherapy