Precision Oncology in Checkpoint Immunotherapy: Leveraging Predictive Biomarkers for Personalized Treatment

13k
Total downloads
58k
Total views and downloads

Articles

ORIGINAL RESEARCH

Accepted on 22 Sep 2025

Predictive Value of Early Changes in Serum CEA, CYFRA21-1, and SCC-Ag for Efficacy and Prognosis in Advanced Lung Squamous Cell Carcinoma Treated with First-Line Immunotherapy Combined with Chemotherapy

Xinyi HUANG
Chuanpeng HU

doi 10.3389/fonc.2025.1561602

129 views

ORIGINAL RESEARCH

Published on 12 Sep 2025

The germinal center-tertiary lymphoid structure after neoadjuvant chemo-immunotherapy for locally advanced lung squamous cell carcinoma can predict the disease progression

Lili Jiang
Shuang Li
Ping Zhou
Yan Huang
Min Chen
Chan Yang

doi 10.3389/fimmu.2025.1579840

719 views

REVIEW

Published on 27 Aug 2025

USP38: an important regulatory factor in tumor malignant progression

Junyan Li
Jinghua Zhong
Jianming Ye
Yi Xiang
Qiang Yi
Gangfeng Zhu
Shifan Deng
Xiangcai Wang

doi 10.3389/fimmu.2025.1612723

814 views

ORIGINAL RESEARCH

Published on 15 Aug 2025

PNI as a predictive biomarker: a novel nomogram of immunotherapy efficacy in advanced breast cancer

Xinyang Li
Xiang Cheng
Yikai Han
Xiaodan Liu
Yujin Fang
Shengju Ren
Xiangwen Dong
Ziwen Lei
Yue Zhang
Tengfei Zhang

doi 10.3389/fonc.2025.1534545

891 views

ORIGINAL RESEARCH

Published on 07 Aug 2025

Evaluation of ctDNA-guided adjuvant therapy de-escalation in head and neck squamous cell carcinoma: a comparative cohort study

Xu Zhang
Qigen Fang
Junhui Yuan
Liyuan Dai
Ruihua Luo
Tao Huang
Yinfei Wu

doi 10.3389/fimmu.2025.1576042

1,137 views

ORIGINAL RESEARCH

Published on 23 Jul 2025

Autonomic nervous system development-related signature as a novel predictive biomarker for immunotherapy in pan-cancers

Cunen Wu
Weiwei Xue
Yuwen Zhuang
Dayue Darrel Duan
Zhou Zhou
Xiaoxiao Wang
Zhenfeng Wu
Jin-yong Zhou
Xiangkun Huan
1 more
Haibo Cheng

doi 10.3389/fimmu.2025.1611890

1,610 views

ORIGINAL RESEARCH

Published on 18 Jul 2025

Quality-of-life scale machine learning approach to predict immunotherapy response in patients with advanced non-small cell lung cancer

Juanyan Shen
Junliang Ma
Shaolin Chen
Su-Han Jin
Junzhu Xu
Qisha Li
Chi Zhang
Xiaojing Tian
Xiaofei Chen
5 more
Jian-Guo Zhou

doi 10.3389/fimmu.2025.1600265

1,524 views

ORIGINAL RESEARCH

Published on 09 Jul 2025

Integrating pathomics and deep learning for subtyping uveal melanoma: identifying high-risk immune infiltration profiles

Qi Wan
Ran Wei
Hongbo Yin
Jing Tang
Ying-ping Deng
Ke Ma

doi 10.3389/fimmu.2025.1585097

1,401 views

ORIGINAL RESEARCH

Published on 05 May 2025

To determine the role of TRIT1 in the diagnosis, prognosis and immunoinvasion of liver hepatocellular carcinoma

Xinyu Niu
Xiaona Pan
Guifang He
Chao Xuan
Qingwu Tian
Yuan Yuan
Jingqiu Chen
Yaqi Song
Yujuan Tang
Tingting Zhou

doi 10.3389/fimmu.2025.1563442

1,611 views

SYSTEMATIC REVIEW

Published on 01 May 2025

The neoadjuvant immunotherapy for non-metastatic mismatch repair-deficient colorectal cancer: a systematic review

Hong-Xia Cui
Xiao-Quan Yang
Guang-yue Zhao
Feng-jian Wang
Xin Liu

doi 10.3389/fimmu.2025.1540751

3,484 views

ORIGINAL RESEARCH

Published on 08 Apr 2025

The transcription factor TSHZ3 promotes tumor immunosuppression and inhibits metastasis in lung adenocarcinoma

Xi Zhang
Yan Liu
Bai-Zhao Peng
Xing-hong Zhou
Yan-ting You
Ying Yang
Shuai Ji
Tian-yu Zhong
Xiao-hu Chen
1 more
Xiao-shan Zhao

doi 10.3389/fimmu.2025.1519815

1,571 views

SYSTEMATIC REVIEW

Published on 26 Mar 2025

The efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy as a first-line treatment for unresectable, locally advanced, HER2-negative gastric or gastroesophageal junction cancer: a meta-analysis of randomized controlled trials

Wenji Pu
Shasha Li
Jinliang Zhang
Jijie Huang
Jishi Li
Yong Jiang
Zhiyuan Xu
Fan Yi
Yuling Lan
2 more
Jing Jin

doi 10.3389/fimmu.2025.1566939

7,508 views
4 citations

Share on

Frontiers in Immunology

Cancer Immunity and Immunotherapy

Participating Journals

Frontiers in Oncology
- Cancer Immunity and Immunotherapy
- 3.3 impact factor
- 6.9 citescore

Impact

58kTopic views
41kArticle views
13kArticle downloads

View impact

Articles

Predictive Value of Early Changes in Serum CEA, CYFRA21-1, and SCC-Ag for Efficacy and Prognosis in Advanced Lung Squamous Cell Carcinoma Treated with First-Line Immunotherapy Combined with Chemotherapy

The germinal center-tertiary lymphoid structure after neoadjuvant chemo-immunotherapy for locally advanced lung squamous cell carcinoma can predict the disease progression

USP38: an important regulatory factor in tumor malignant progression

PNI as a predictive biomarker: a novel nomogram of immunotherapy efficacy in advanced breast cancer

Evaluation of ctDNA-guided adjuvant therapy de-escalation in head and neck squamous cell carcinoma: a comparative cohort study

Autonomic nervous system development-related signature as a novel predictive biomarker for immunotherapy in pan-cancers

Quality-of-life scale machine learning approach to predict immunotherapy response in patients with advanced non-small cell lung cancer

Integrating pathomics and deep learning for subtyping uveal melanoma: identifying high-risk immune infiltration profiles

To determine the role of TRIT1 in the diagnosis, prognosis and immunoinvasion of liver hepatocellular carcinoma

The neoadjuvant immunotherapy for non-metastatic mismatch repair-deficient colorectal cancer: a systematic review

The transcription factor TSHZ3 promotes tumor immunosuppression and inhibits metastasis in lung adenocarcinoma

The efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy as a first-line treatment for unresectable, locally advanced, HER2-negative gastric or gastroesophageal junction cancer: a meta-analysis of randomized controlled trials

Frontiers in Immunology

Cancer Immunity and Immunotherapy

Participating Journals

Frontiers in Oncology

Cancer Immunity and Immunotherapy