Cancer Therapy Related Organ Toxicities

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Articles

CASE REPORT

Published on 12 Nov 2025

Case Report: Accelerated parathyroid adenoma progression and hypercalcemia-driven neurotoxicity following pembrolizumab-based neoadjuvant therapy in triple-negative breast cancer: a case of multisystem immune-related adverse events

Yi Zeng
Yu Sun
Pengfei Qian

doi 10.3389/fonc.2025.1607957

155 views

CASE REPORT

Published on 28 Oct 2025

Immune-related osteitis mimicking femoral head osteonecrosis during dual checkpoint blockade: a case report

Enrica Teresa Tanda
Agostina Lagodin D’Amato
Giovanni Rossi
Maria Maddalena Latocca
Andrea Boutros
Andrea Zanirato
Matteo Formica
Silvia Bozzano
Bruno Spina
Francesco Spagnolo

doi 10.3389/fonc.2025.1621774

578 views

ORIGINAL RESEARCH

Published on 07 Oct 2025

Risk factors for steroid-refractory in immune checkpoint inhibitor-induced colitis: a retrospective cohort study

Ke Meng
Jing Chen
Junzhe Chen
Shengjie Sun
Hui Li
Guanzhou Zhou
Fei Pan

doi 10.3389/fimmu.2025.1623150

675 views

ORIGINAL RESEARCH

Published on 03 Oct 2025

Immune checkpoint inhibitor-associated aseptic meningitis: a pharmacovigilance study using the FDA adverse event reporting system (2011–2024)

Hui Guo
Yuzhu Pang
Qian Guo
Ze Wang
Haixiong Wang

doi 10.3389/fimmu.2025.1654301

1,249 views
1 citation

CASE REPORT

Published on 30 Sep 2025

Case Report: A case of reversible pulmonary bullae induced by camrelizumab: a new immune-related adverse event

Yun Wang
Shaoshan Wang
Qin Li
Qihao Cui
Jiafu Song
Hong Zheng

doi 10.3389/fimmu.2025.1619702

919 views

ORIGINAL RESEARCH

Published on 25 Sep 2025

Increased acid sphingomyelinase levels in saliva as oral mucositis severity predictors

Elsa Beatriz Monroy Ordonez
Tanja Sprave
Andreas R. Thomsen
Henning Schäfer
Anca-Ligia Grosu
Verena Jendrossek
Michael Henke
Kristian Unger
Diana Klein

doi 10.3389/fonc.2025.1613884

2,768 views

CASE REPORT

Published on 10 Sep 2025

Successful rescue of PD-1 inhibitor-induced TEN by vincristine combination therapy: a case report and literature review

Hui-Yi Huang
Jia-Qi Liu
Yun-Yun Zeng
Zhi-Hao Huang
Shan Su

doi 10.3389/fonc.2025.1621494

836 views
1 citation

ORIGINAL RESEARCH

Published on 13 Aug 2025

Clinical features and risk factors of immune-mediated liver injury in non-small cell lung cancer patients treated with immune checkpoint inhibitors

Ling Yang
Chao Zhuo
Chonghuan Li
Yujing Liu
Xinyi Liu
Yibin Huang
Bingbing Wu
Jiawei Su

doi 10.3389/fonc.2025.1575376

1,046 views

CASE REPORT

Published on 25 Jun 2025

Case Report: Immune checkpoint inhibitor-induced myositis without elevated creatine kinase

Klajdi Begaj
Raphael Wilhelm
Alisa Lepper
Maike Kaufhold
Jakob Veeser
Stephan Grabbe
Henner Stege

doi 10.3389/fimmu.2025.1592385

1,768 views

ORIGINAL RESEARCH

Published on 09 Jun 2025

Insights into immune-related adverse events in colorectal cancer patients receiving neoadjuvant immunotherapy: findings from a multicenter registry study

Chentong Wang
Quan Wang
Jiaolin Zhou
Aiping Zhou
Xiaojian Wu
Guanyu Yu
Lei Zhou
Yuping Zhu
Weijie Chen
11 more
Wei Zhang

doi 10.3389/fimmu.2025.1529637

2,379 views

ORIGINAL RESEARCH

Published on 28 Apr 2025

Moderate toxicity with late onset as a good omen: association between toxicity and survival in the checkpoint inhibitor immunotherapy—a single center experience

Anna Rudzińska
Pola Juchaniuk
Jakub Oberda
Kamila Krukowska
Sylwia Krzyśkowska
Eliza Kuchta
Anna Rodzajewska
Mariola Janiszewska
Katarzyna Machulska-Ciuraj
Katarzyna Szklener

doi 10.3389/fimmu.2025.1527103

1,591 views

CASE REPORT

Published on 04 Apr 2025

Case Report: Successful use of emapalumab in adult B-cell acute lymphoblastic leukemia experiencing severe neurotoxicity and hemophagocytic lymphohistiocytosis-like features after CAR-T cell therapy

Beatrice Manghisi
Giulia Cotilli
Marilena Fedele
Paola Perfetti
Elisabetta Terruzzi
Luisa Verga
Lorenza Maria Borin
Andrea Carrer
Monica Fumagalli
15 more
Andrea Aroldi

doi 10.3389/fimmu.2025.1563736

5,236 views
1 citation

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Cancer Immunity and Immunotherapy

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- Cancer Immunity and Immunotherapy
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Articles

Case Report: Accelerated parathyroid adenoma progression and hypercalcemia-driven neurotoxicity following pembrolizumab-based neoadjuvant therapy in triple-negative breast cancer: a case of multisystem immune-related adverse events

Immune-related osteitis mimicking femoral head osteonecrosis during dual checkpoint blockade: a case report

Risk factors for steroid-refractory in immune checkpoint inhibitor-induced colitis: a retrospective cohort study

Immune checkpoint inhibitor-associated aseptic meningitis: a pharmacovigilance study using the FDA adverse event reporting system (2011–2024)

Case Report: A case of reversible pulmonary bullae induced by camrelizumab: a new immune-related adverse event

Increased acid sphingomyelinase levels in saliva as oral mucositis severity predictors

Successful rescue of PD-1 inhibitor-induced TEN by vincristine combination therapy: a case report and literature review

Clinical features and risk factors of immune-mediated liver injury in non-small cell lung cancer patients treated with immune checkpoint inhibitors

Case Report: Immune checkpoint inhibitor-induced myositis without elevated creatine kinase

Insights into immune-related adverse events in colorectal cancer patients receiving neoadjuvant immunotherapy: findings from a multicenter registry study

Moderate toxicity with late onset as a good omen: association between toxicity and survival in the checkpoint inhibitor immunotherapy—a single center experience

Case Report: Successful use of emapalumab in adult B-cell acute lymphoblastic leukemia experiencing severe neurotoxicity and hemophagocytic lymphohistiocytosis-like features after CAR-T cell therapy

Frontiers in Immunology

Cancer Immunity and Immunotherapy

Participating Journals

Frontiers in Oncology

Cancer Immunity and Immunotherapy