Application of New Approach Methodologies in Toxicological Assessment of Next Generation Tobacco and Nicotine Products

1,385
Total downloads
9,352
Total views and downloads

Articles

ORIGINAL RESEARCH

Accepted on 09 Sep 2025

Acetaldehyde and Methylglyoxal: Comparative Analysis of Toxic Electronic Cigarette Degradation Products in 3D and 2D Exposure Systems using Human Bronchial Epithelial Models

Man Wong
Teresa Martinez
Nathan Hendricks
Prue Talbot

doi 10.3389/ftox.2025.1624794

226 views

ORIGINAL RESEARCH

Published on 15 May 2025

Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation

Shigeaki Ito
Sakuya Ichikawa
Risa Matsumoto
Shugo Muratani
Keigo Sano
Akina Mori
Kazuo Erami

doi 10.3389/ftox.2025.1564864

1,076 views

ORIGINAL RESEARCH

Published on 15 May 2025

Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based in vitro assessment with repeated exposure to whole cigarette smoke

Sakuya Ichikawa
Shugo Muratani
Keigo Sano
Kazuo Erami
Akina Mori
Risa Matsumoto
Shigeaki Ito

doi 10.3389/ftox.2025.1564857

1,177 views

ORIGINAL RESEARCH

Published on 13 Jun 2024

Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

Fiona Chapman
Luuk de Haan
Linda Gijzen
Wouter Strijker
Edgar Trelles Sticken
Sarah Jean Pour
Roman Wieczorek
Florian Haberstroh
Sandra Otte
2 more
Matthew Stevenson

doi 10.3389/ftox.2024.1395670

4,265 views
1 citation

Share on

Frontiers in Toxicology

Frontiers in Toxicology

Regulatory Toxicology
Computational Toxicology and Informatics
In Vitro Toxicology
Immunotoxicology

Impact

9,352Topic views
6,508Article views
1,385Article downloads